Phyre 2 Results for O88890

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Email | l.a.kelley@imperial.ac.uk
Description | O88890
Date | Wed Jul 10 14:08:25 BST 2013
Unique Job ID | 8b2bbfb33b9c3421
Sequence | MDAVTVYHGK ... Download FASTA

Summary |

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å): | X:38.546 Y:33.667 Z:30.260
| Close Jmol

Model (left) based on template c1ka6A_
Top template information
PDB header:immune system Chain: A: PDB Molecule:sh2 domain protein 1a; PDBTitle: sap/sh2d1a bound to peptide n-py
Confidence and coverage
Confidence: | 100.0% | Coverage: | 84%
106 residues ( 84% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | D | A | V | T | V | Y | H | G | K | I | S | R | E | T | G | E | K | L | L | L | A | T | G | L | D | G | S | Y | L | L | R | D | S | E | S | V | P | G | V | Y | C | L | C | V | L | Y | Q | G | Y | I | Y | T | Y | R | V | S | Q | T | E
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | T | G | S | W | S | A | E | T | A | P | G | V | H | K | R | F | F | R | K | V | K | N | L | I | S | A | F | Q | K | P | D | Q | G | I | V | T | P | L | Q | Y | P | V | E | K | S | S | G | R | G | P | Q | A | P | T | G | R | R | D | S | D
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | .
Sequence |  | I | C | L | N | A | P
Secondary structure |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |
Disorder |  |  | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)
? | Disordered ( 22%)
| Alpha helix ( 15%)
| Beta strand ( 25%)

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| c1ka6A_ |

### PDB 1ka6 chain A

Region: 1 - 106
Aligned: 106
Modelled: 106
Confidence: 100.0%
Identity: 94%
PDB header:immune system
Chain: A: PDB Molecule:sh2 domain protein 1a;
PDBTitle: sap/sh2d1a bound to peptide n-py

Phyre2
2 |
| d1d4ta_ |

### PDB 1d4t chain A

Region: 1 - 104
Aligned: 104
Modelled: 104
Confidence: 100.0%
Identity: 95%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
3 |
| d1a81e1 |

### PDB 1a81 chain E domain 1

Region: 1 - 112
Aligned: 107
Modelled: 112
Confidence: 100.0%
Identity: 26%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
4 |
| d2oq1a1 |

### PDB 2oq1 chain A domain 1

Region: 1 - 112
Aligned: 107
Modelled: 112
Confidence: 100.0%
Identity: 23%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
5 |
| d1i3za_ |

### PDB 1i3z chain A

Region: 3 - 104
Aligned: 102
Modelled: 101
Confidence: 100.0%
Identity: 38%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
6 |
| c2ysxA_ |

### PDB 2ysx chain A

Region: 5 - 113
Aligned: 109
Modelled: 109
Confidence: 100.0%
Identity: 42%
PDB header:signaling protein
Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase
PDBTitle: solution structure of the human ship sh2 domain

Phyre2
7 |
| c2oq1A_ |

### PDB 2oq1 chain A

Region: 1 - 113
Aligned: 108
Modelled: 113
Confidence: 100.0%
Identity: 23%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide

Phyre2
8 |
| c2dlyA_ |

### PDB 2dly chain A

Region: 1 - 112
Aligned: 107
Modelled: 112
Confidence: 100.0%
Identity: 27%
PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase

Phyre2
9 |
| d1a81a1 |

### PDB 1a81 chain A domain 1

Region: 1 - 114
Aligned: 109
Modelled: 114
Confidence: 100.0%
Identity: 26%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
10 |
| c4fl2A_ |

### PDB 4fl2 chain A

Region: 1 - 113
Aligned: 108
Modelled: 113
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch

Phyre2
11 |
| c2gsbA_ |

### PDB 2gsb chain A

Region: 1 - 112
Aligned: 106
Modelled: 112
Confidence: 99.9%
Identity: 25%
PDB header:signaling protein
Chain: A: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1

Phyre2
12 |
| d2oq1a2 |

### PDB 2oq1 chain A domain 2

Region: 2 - 104
Aligned: 97
Modelled: 103
Confidence: 99.9%
Identity: 26%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
13 |
| d1a81e2 |

### PDB 1a81 chain E domain 2

Region: 2 - 104
Aligned: 97
Modelled: 103
Confidence: 99.9%
Identity: 31%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
14 |
| c2ozoA_ |

### PDB 2ozo chain A

Region: 3 - 113
Aligned: 106
Modelled: 111
Confidence: 99.9%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70

Phyre2
15 |
| d1blja_ |

### PDB 1blj chain A

Region: 1 - 106
Aligned: 101
Modelled: 106
Confidence: 99.9%
Identity: 25%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
16 |
| d1lkka_ |

### PDB 1lkk chain A

Region: 1 - 103
Aligned: 98
Modelled: 103
Confidence: 99.9%
Identity: 26%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
17 |
| c2eo6A_ |

### PDB 2eo6 chain A

Region: 1 - 109
Aligned: 109
Modelled: 109
Confidence: 99.9%
Identity: 25%
PDB header:signaling protein
Chain: A: PDB Molecule:b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk

Phyre2
18 |
| d1csya_ |

### PDB 1csy chain A

Region: 1 - 106
Aligned: 100
Modelled: 101
Confidence: 99.9%
Identity: 30%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
19 |
| d1a81a2 |

### PDB 1a81 chain A domain 2

Region: 2 - 104
Aligned: 97
Modelled: 103
Confidence: 99.9%
Identity: 31%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
20 |
| c2ge9A_ |

### PDB 2ge9 chain A

Region: 1 - 112
Aligned: 106
Modelled: 112
Confidence: 99.9%
Identity: 27%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase btk;
PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | c1ka6A_ |
|  | 100.0 | 94 | PDB header:immune system Chain: A: PDB Molecule:sh2 domain protein 1a; PDBTitle: sap/sh2d1a bound to peptide n-py
2 | d1d4ta_ |
|  | 100.0 | 95 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
3 | d1a81e1 |
|  | 100.0 | 26 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
4 | d2oq1a1 |
|  | 100.0 | 23 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
5 | d1i3za_ |
|  | 100.0 | 38 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
6 | c2ysxA_ |
|  | 100.0 | 42 | PDB header:signaling protein Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase PDBTitle: solution structure of the human ship sh2 domain
7 | c2oq1A_ |
|  | 100.0 | 23 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
8 | c2dlyA_ |
|  | 100.0 | 27 | PDB header:transferase Chain: A: PDB Molecule:fyn-related kinase; PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
9 | d1a81a1 |
|  | 100.0 | 26 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
10 | c4fl2A_ |
|  | 100.0 | 26 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch
11 | c2gsbA_ |
|  | 99.9 | 25 | PDB header:signaling protein Chain: A: PDB Molecule:ras gtpase-activating protein 1; PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
12 | d2oq1a2 |
|  | 99.9 | 26 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
13 | d1a81e2 |
|  | 99.9 | 31 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
14 | c2ozoA_ |
|  | 99.9 | 24 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
15 | d1blja_ |
|  | 99.9 | 25 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
16 | d1lkka_ |
|  | 99.9 | 26 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
17 | c2eo6A_ |
|  | 99.9 | 25 | PDB header:signaling protein Chain: A: PDB Molecule:b-cell linker protein; PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
18 | d1csya_ |
|  | 99.9 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
19 | d1a81a2 |
|  | 99.9 | 31 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
20 | c2ge9A_ |
|  | 99.9 | 27 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
21 | d1rjaa_ |
| not modelled | 99.9 | 23 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
22 | d1opka2 |
| not modelled | 99.9 | 33 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
23 | c2augB_ |
| not modelled | 99.9 | 23 | PDB header:signaling protein Chain: B: PDB Molecule:growth factor receptor-bound protein 14; PDBTitle: crystal structure of the grb14 sh2 domain
24 | d1k9aa2 |
| not modelled | 99.9 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
25 | d1nrva_ |
| not modelled | 99.9 | 25 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
26 | d1jwoa_ |
| not modelled | 99.9 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
27 | d1o48a_ |
| not modelled | 99.9 | 28 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
28 | d2shpa2 |
| not modelled | 99.9 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
29 | c2ablA_ |
| not modelled | 99.9 | 33 | PDB header:transferase Chain: A: PDB Molecule:abl tyrosine kinase; PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
30 | d1qcfa2 |
| not modelled | 99.9 | 28 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
31 | d1f2fa_ |
| not modelled | 99.9 | 28 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
32 | c2fo0A_ |
| not modelled | 99.9 | 30 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
33 | d2qmsa1 |
| not modelled | 99.9 | 24 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
34 | c1a81E_ |
| not modelled | 99.9 | 27 | PDB header:complex (transferase/peptide) Chain: E: PDB Molecule:syk kinase; PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
35 | d1luia_ |
| not modelled | 99.9 | 34 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
36 | c2eobA_ |
| not modelled | 99.9 | 20 | PDB header:hydrolase Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
37 | d3c7ia1 |
| not modelled | 99.9 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
38 | d1fhsa_ |
| not modelled | 99.9 | 22 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
39 | c2dm0A_ |
| not modelled | 99.9 | 25 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase txk; PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk
40 | d1g83a2 |
| not modelled | 99.9 | 26 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
41 | c3hizB_ |
| not modelled | 99.9 | 27 | PDB header:transferase/oncoprotein Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
42 | d1bkla_ |
| not modelled | 99.9 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
43 | c2ekxA_ |
| not modelled | 99.9 | 28 | PDB header:signaling protein Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx; PDBTitle: solution structure of the human bmx sh2 domain
44 | c1x27F_ |
| not modelled | 99.9 | 23 | PDB header:signaling protein Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck; PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
45 | c2eo3A_ |
| not modelled | 99.9 | 24 | PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
46 | c1y57A_ |
| not modelled | 99.9 | 25 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
47 | c3nhnA_ |
| not modelled | 99.9 | 28 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
48 | c2lqnA_ |
| not modelled | 99.9 | 19 | PDB header:signaling protein Chain: A: PDB Molecule:crk-like protein; PDBTitle: solution structure of crkl
49 | d2izva2 |
| not modelled | 99.9 | 20 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
50 | c2hdxB_ |
| not modelled | 99.9 | 24 | PDB header:signaling protein Chain: B: PDB Molecule:sh2-b ph domain containing signaling mediator 1 PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide
51 | c1oplA_ |
| not modelled | 99.9 | 30 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
52 | c1x6cA_ |
| not modelled | 99.9 | 27 | PDB header:signaling protein Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
53 | c2y3aB_ |
| not modelled | 99.9 | 31 | PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta; PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
54 | c2shpA_ |
| not modelled | 99.9 | 26 | PDB header:tyrosine phosphatase Chain: A: PDB Molecule:shp-2; PDBTitle: tyrosine phosphatase shp-2
55 | c2crhA_ |
| not modelled | 99.9 | 23 | PDB header:signaling protein Chain: A: PDB Molecule:vav proto-oncogene; PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
56 | c2h8hA_ |
| not modelled | 99.9 | 25 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor
57 | d2fcia1 |
| not modelled | 99.9 | 24 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
58 | c2c9wA_ |
| not modelled | 99.9 | 18 | PDB header:transcription regulation Chain: A: PDB Molecule:suppressor of cytokine signaling 2; PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
59 | c2dlzA_ |
| not modelled | 99.9 | 20 | PDB header:signaling protein Chain: A: PDB Molecule:protein vav-2; PDBTitle: solution structure of the sh2 domain of human protein vav-2
60 | d1pica_ |
| not modelled | 99.9 | 31 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
61 | c2el8A_ |
| not modelled | 99.9 | 15 | PDB header:signaling protein Chain: A: PDB Molecule:signal-transducing adaptor protein 2; PDBTitle: solution structure of the human stap2 sh2 domain
62 | c2hmhA_ |
| not modelled | 99.9 | 19 | PDB header:cytokine regulator Chain: A: PDB Molecule:suppressor of cytokine signaling 3; PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
63 | c3mazA_ |
| not modelled | 99.9 | 18 | PDB header:signaling protein Chain: A: PDB Molecule:signal-transducing adaptor protein 1; PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide
64 | c2c0iA_ |
| not modelled | 99.9 | 25 | PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983
65 | d1ayaa_ |
| not modelled | 99.9 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
66 | c2knoA_ |
| not modelled | 99.9 | 22 | PDB header:hydrolase Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase; PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
67 | c2lctA_ |
| not modelled | 99.9 | 23 | PDB header:signaling protein Chain: A: PDB Molecule:proto-oncogene vav; PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
68 | c1k9aB_ |
| not modelled | 99.9 | 30 | PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
69 | c2ci8A_ |
| not modelled | 99.9 | 28 | PDB header:translation Chain: A: PDB Molecule:cytoplasmic protein nck1; PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
70 | c2vifA_ |
| not modelled | 99.9 | 24 | PDB header:signaling protein Chain: A: PDB Molecule:suppressor of cytokine signalling 6; PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
71 | d2cs0a1 |
| not modelled | 99.9 | 27 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
72 | d2eyva1 |
| not modelled | 99.9 | 24 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
73 | c3ps5A_ |
| not modelled | 99.9 | 20 | PDB header:hydrolase, signaling protein Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6; PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
74 | c2izvA_ |
| not modelled | 99.9 | 19 | PDB header:transcription Chain: A: PDB Molecule:suppressor of cytokine signaling 4; PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
75 | c2b3oA_ |
| not modelled | 99.9 | 20 | PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type PDBTitle: crystal structure of human tyrosine phosphatase shp-1
76 | d1jyra_ |
| not modelled | 99.9 | 24 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
77 | d2shpa3 |
| not modelled | 99.9 | 30 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
78 | c2kk6A_ |
| not modelled | 99.9 | 27 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer; PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
79 | c3gqiB_ |
| not modelled | 99.9 | 26 | PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:phospholipase c-gamma-1; PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
80 | d1mila_ |
| not modelled | 99.9 | 34 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
81 | d1cwea_ |
| not modelled | 99.9 | 28 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
82 | c1g83A_ |
| not modelled | 99.9 | 26 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn; PDBTitle: crystal structure of fyn sh3-sh2
83 | d1r1qa_ |
| not modelled | 99.9 | 21 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
84 | d1fu6a_ |
| not modelled | 99.9 | 28 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
85 | d1qada_ |
| not modelled | 99.9 | 33 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
86 | c2dcrA_ |
| not modelled | 99.9 | 25 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps; PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
87 | d1rpya_ |
| not modelled | 99.9 | 28 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
88 | d2c9wa2 |
| not modelled | 99.9 | 16 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
89 | c1rqqC_ |
| not modelled | 99.8 | 29 | PDB header:transferase/signaling protein Chain: C: PDB Molecule:adaptor protein aps; PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
90 | c2eyzA_ |
| not modelled | 99.8 | 21 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform ii
91 | d1xa6a2 |
| not modelled | 99.8 | 25 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
92 | c2dvjA_ |
| not modelled | 99.8 | 19 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog, PDBTitle: phosphorylated crk-ii
93 | c3qwxX_ |
| not modelled | 99.7 | 24 | PDB header:signaling protein Chain: X: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2 1-174
94 | c2eyyA_ |
| not modelled | 99.7 | 20 | PDB header:signaling protein Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog PDBTitle: ct10-regulated kinase isoform i
95 | c3qwyA_ |
| not modelled | 99.7 | 25 | PDB header:signaling protein Chain: A: PDB Molecule:cell death abnormality protein 2; PDBTitle: ced-2
96 | c3gxxB_ |
| not modelled | 99.7 | 12 | PDB header:transcription Chain: B: PDB Molecule:transcription elongation factor spt6; PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b
97 | c2cr4A_ |
| not modelled | 99.7 | 19 | PDB header:signaling protein Chain: A: PDB Molecule:sh3 domain-binding protein 2; PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
98 | c2dx0B_ |
| not modelled | 99.7 | 26 | PDB header:hydrolase Chain: B: PDB Molecule:phospholipase c, gamma 2; PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2
99 | c3or8A_ |
| not modelled | 99.6 | 11 | PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor spt6; PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
100 | c2xp1A_ |
| not modelled | 99.6 | 14 | PDB header:transcription Chain: A: PDB Molecule:spt6; PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
101 | d1bf5a3 |
| not modelled | 99.5 | 21 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
102 | c1xa6A_ |
| not modelled | 99.4 | 34 | PDB header:signaling protein Chain: A: PDB Molecule:beta2-chimaerin; PDBTitle: crystal structure of the human beta2-chimaerin
103 | d1uura3 |
| not modelled | 99.4 | 25 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
104 | d1bg1a3 |
| not modelled | 99.2 | 21 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
105 | c3cblA_ |
| not modelled | 99.1 | 28 | PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps; PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide
106 | c2cblA_ |
| not modelled | 98.2 | 14 | PDB header:complex (proto-oncogene/peptide) Chain: A: PDB Molecule:proto-oncogene cbl; PDBTitle: n-terminal domain of cbl in complex with its binding site2 on zap-70
107 | c3bunB_ |
| not modelled | 98.2 | 14 | PDB header:ligase/signaling protein Chain: B: PDB Molecule:e3 ubiquitin-protein ligase cbl; PDBTitle: crystal structure of c-cbl-tkb domain complexed with its2 binding motif in sprouty4
108 | c1uusA_ |
| not modelled | 98.1 | 19 | PDB header:signal transduction Chain: A: PDB Molecule:stat protein; PDBTitle: structure of an activated dictyostelium stat in its2 dna-unbound form
109 | c1y1uA_ |
| not modelled | 97.9 | 27 | PDB header:signaling protein Chain: A: PDB Molecule:signal transducer and activator of transcription 5a; PDBTitle: structure of unphosphorylated stat5a
110 | c1bg1A_ |
| not modelled | 97.7 | 22 | PDB header:transcription/dna Chain: A: PDB Molecule:protein (transcription factor stat3b); PDBTitle: transcription factor stat3b/dna complex
111 | c1yvlB_ |
| not modelled | 97.7 | 32 | PDB header:signaling protein Chain: B: PDB Molecule:signal transducer and activator of transcription PDBTitle: structure of unphosphorylated stat1
112 | c1bf5A_ |
| not modelled | 97.6 | 33 | PDB header:gene regulation/dna Chain: A: PDB Molecule:signal transducer and activator of transcription PDBTitle: tyrosine phosphorylated stat-1/dna complex
113 | c3cwgA_ |
| not modelled | 96.2 | 34 | PDB header:transcription Chain: A: PDB Molecule:signal transducer and activator of transcription PDBTitle: unphosphorylated mouse stat3 core fragment
114 | c1fbvA_ |
| not modelled | 94.0 | 14 | PDB header:ligase Chain: A: PDB Molecule:signal transduction protein cbl; PDBTitle: structure of a cbl-ubch7 complex: ring domain function in2 ubiquitin-protein ligases
115 | d3buxb3 |
| not modelled | 91.8 | 14 | Fold:SH2-like Superfamily:SH2 domain Family:SH2 domain
116 | c3op0B_ |
| not modelled | 87.0 | 16 | PDB header:signaling protein/signaling protein regu Chain: B: PDB Molecule:signal transduction protein cbl-c; PDBTitle: crystal structure of cbl-c (cbl-3) tkb domain in complex with egfr2 py1069 peptide
117 | c1griA_ |
| not modelled | 80.4 | 21 | PDB header:signal transduction adaptor Chain: A: PDB Molecule:growth factor bound protein 2; PDBTitle: grb2
118 | c1x60A_ |
| not modelled | 35.7 | 17 | PDB header:hydrolase Chain: A: PDB Molecule:sporulation-specific n-acetylmuramoyl-l-alanine PDBTitle: solution structure of the peptidoglycan binding domain of2 b. subtilis cell wall lytic enzyme cwlc
119 | d1wlha1 |
| not modelled | 34.9 | 21 | Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Filamin repeat (rod domain)
120 | c1ksrA_ |
| not modelled | 33.3 | 21 | PDB header:actin binding protein Chain: A: PDB Molecule:gelation factor; PDBTitle: the repeating segments of the f-actin cross-linking2 gelation factor (abp-120) have an immunoglobulin fold, nmr,3 20 structures

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