Job Description P06240 Confidence 100.00% Date Wed Jul 10 14:01:50 BST 2013 Rank 8 Aligned Residues 368 % Identity 39% Template c4fl2A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase syk; PDBTitle: structural and biophysical characterization of the syk activation2 switch Resolution 2.19 Å Model Dimensions (Å) X:92.049 Y:63.057 Z:51.735

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		123	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	P	E	P	W	F	F	K	N	L	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	T	H	G	S	F	L	I	R	E	S	E	S	T	A	G	S	F	S	L	S	V	R	D	F	D	Q	N	Q	G	E	V	V	K	H	Y	K
Query Conservation
Alig confidence																																					.															.	.	.	.	.
Template Conservation																																					.															.	.	.	.	.
Template Sequence		E	K	M	P	W	F	H	G	K	I	S	R	E	E	S	E	Q	I	V	L	I	G	S	K	T	N	G	K	F	L	I	R	A	R	D	.	N	N	G	S	Y	A	L	C	L	L	H	E	G	K	.	.	.	.	.	V	L	H	Y	R
Template Known Secondary structure		G	G	S	T	T	B			S												S	S	S			T	T									.	T	T	T									T	T		.	.	.	.	.
Template Predicted Secondary structure																																					.															.	.	.	.	.
Template SS confidence
		164	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.		.	200	.	.	.	.	.	.	.	.	.	210	.	.						.	.	.	.	.
		183	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.
Predicted Secondary structure																																																				.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																				.	.	.	.	.	.	.	.	.	.
Query Sequence		I	R	N	L	D	N	G	G	F	Y	I	S	P	R	I	T	F	P	G	L	H	D	L	V	R	H	Y	T	N	A	S	D	G	L	C	T	K	L	S	R	P	C	Q	T	Q	K	P	Q	K	P	.	.	.	.	.	.	.	.	.	.
Query Conservation																																																				.	.	.	.	.	.	.	.	.	.
Alig confidence																																																				.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		I	D	K	D	K	T	G	K	L	S	I	P	E	G	K	K	F	D	T	L	W	Q	L	V	E	H	Y	S	Y	K	A	D	G	L	L	R	V	L	T	V	P	C	Q	K	I	G	T	Q	R	E	A	L	P	M	D	T	E	V	Y	E
Template Known Secondary structure						T	T	S				S	T	T				B	S	S									T	T	B		T	T	S	S	S				S	B				S				T	T			G	G	G	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		218	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.
			233	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250									.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.				.	.	270	.	.	.	.	.	.	.	.
Predicted Secondary structure		.																			.	.	.	.	.	.	.	.																		.	.	.												.	.
Query SS confidence		.																			.	.	.	.	.	.	.	.																		.	.	.												.	.
Query Sequence		.	W	W	E	D	E	W	E	V	P	R	E	T	L	K	L	V	E	R	.	.	.	.	.	.	.	.	L	G	A	G	Q	F	G	E	V	W	M	G	Y	Y	N	G	H	.	.	.	T	K	V	A	V	K	S	L	K	Q	G	.	.
Query Conservation		.																			.	.	.	.	.	.	.	.																		.	.	.												.	.
Alig confidence		.																			.	.	.	.	.	.	.	.																		.	.	.												.	.
Template Conservation
Template Sequence		S	P	Y	A	D	P	E	E	I	R	P	K	E	V	Y	L	D	R	K	L	L	T	L	E	D	K	E	L	G	S	G	N	F	G	T	V	K	K	G	Y	Y	Q	M	K	K	V	V	K	T	V	A	V	K	I	L	K	N	E	A	N
Template Known Secondary structure			G	G	G	S	T	T	S				S	S	S	B			G	G	G												T	T											T	T												S	G	G	G
Template Predicted Secondary structure
Template SS confidence
		350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.
			279	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.
Predicted Secondary structure		.
Query SS confidence		.
Query Sequence		.	S	M	S	P	D	A	F	L	A	E	A	N	L	M	K	Q	L	Q	H	P	R	L	V	R	L	Y	A	V	V	T	Q	E	P	I	Y	I	I	T	E	Y	M	E	N	G	S	L	V	D	F	L	K	T	P	S	G	I	K	L	N
Query Conservation		.
Alig confidence		.																																																							.	.
Template Conservation																																																									.	.
Template Sequence		D	P	A	L	K	D	E	L	L	A	E	A	N	V	M	Q	Q	L	D	N	P	Y	I	V	R	M	I	G	I	C	E	A	E	S	W	M	L	V	M	E	M	A	E	L	G	P	L	N	K	Y	L	Q	Q	N	R	.	.	H	V	K
Template Known Secondary structure			G	G	G																	T	T	B									S	S	S									T	T		B									T	.	.	T	S
Template Predicted Secondary structure																																																									.	.
Template SS confidence
		410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.			.	.	.
		338	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.			.	.
Predicted Secondary structure																																																										.	.
Query SS confidence																																																										.	.
Query Sequence		V	N	K	L	L	D	M	A	A	Q	I	A	E	G	M	A	F	I	E	E	Q	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	D	T	L	S	C	K	I	A	D	F	G	L	A	R	L	I	E	D	N	E	.	.	Y	T
Query Conservation																																																										.	.
Alig confidence																																																										.	.
Template Conservation
Template Sequence		D	K	N	I	I	E	L	V	H	Q	V	S	M	G	M	K	Y	L	E	E	S	N	F	V	H	R	D	L	A	A	R	N	V	L	L	V	T	Q	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	R	A	D	E	N	Y	Y	K
Template Known Secondary structure																						T	T				S			S	G	G	G						T	T							T	T					T	T
Template Predicted Secondary structure
Template SS confidence
		468	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.
		396	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	R	E	G	A	K	F	P	I	K	W	T	A	P	E	A	I	N	Y	G	T	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	I	V	T	H	G	R	I	P	Y	P	G	M	T	N	P	E	V	I	Q	N	L	E	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	Q	T	H	G	K	W	P	V	K	W	Y	A	P	E	C	I	N	Y	Y	K	F	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	A	F	S	Y	G	Q	K	P	Y	R	G	M	K	G	S	E	V	T	A	M	L	E	K
Template Known Secondary structure		S		B	T	T	B		G	G	G	G																													T	T	T			S	S	T	T												T
Template Predicted Secondary structure
Template SS confidence
		528	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.
		456	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	Y	R	M	V	R	P	D	N	C	P	E	E	L	Y	H	L	M	M	L	C	W	K	E	R	P	E	D	R	P	T	F	D	Y	L	R	S	V	L	D	D	F	F
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	E	R	M	G	C	P	A	G	C	P	R	E	M	Y	D	L	M	N	L	C	W	T	Y	D	V	E	N	R	P	G	F	A	A	V	E	L	R	L	R	N	Y	Y
Template Known Secondary structure		T							T	T													T		S	S	T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		588	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D