Job Description P06240 Confidence 100.00% Date Wed Jul 10 14:01:50 BST 2013 Rank 309 Aligned Residues 256 % Identity 25% Template c3ttjA_ PDB info PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:mitogen-activated protein kinase 10; PDBTitle: crystal structure of jnk3 complexed with cc-359, a jnk inhibitor for2 the prevention of ischemia-reperfusion injury Resolution 2.10 Å

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		236	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.		.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.				.	.	.	.	.	.	.	290	.
Predicted Secondary structure																																	.																	.	.	.
Query SS confidence																																	.																	.	.	.
Query Sequence		D	E	W	E	V	P	R	E	T	L	K	L	V	E	R	L	G	A	G	Q	F	G	E	V	W	M	G	Y	Y	N	G	.	H	T	K	V	A	V	K	S	L	K	Q	G	S	M	S	P	.	.	.	D	A	F	L	A	E	A	N	L
Query Conservation																																	.																	.	.	.
Alig confidence								.																									.																	.	.	.
Template Conservation								.
Template Sequence		S	T	F	T	V	L	.	K	R	Y	Q	N	L	K	P	I	G	S	G	A	Q	G	I	V	C	A	A	Y	D	A	V	L	D	R	N	V	A	I	K	K	L	S	R	P	F	Q	N	Q	T	H	A	K	R	A	Y	R	E	L	V	L
Template Known Secondary structure								.	T	T											S	S									T	T	T	T										S	G	G	G	S
Template Predicted Secondary structure								.
Template SS confidence
		56	.	.	.	60	.		.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.
		292	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.								.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.
Predicted Secondary structure																			.	.	.	.	.	.	.
Query SS confidence																			.	.	.	.	.	.	.
Query Sequence		M	K	Q	L	Q	H	P	R	L	V	R	L	Y	A	V	V	T	.	.	.	.	.	.	.	Q	E	P	I	Y	I	I	T	E	Y	M	E	N	G	S	L	V	D	F	L	K	T	P	S	G	I	K	L	N	V	N	K	L	L	D	M
Query Conservation																			.	.	.	.	.	.	.
Alig confidence																			.	.	.	.	.	.	.																								.	.	.	.	.
Template Conservation																																																	.	.	.	.	.
Template Sequence		M	K	C	V	N	H	K	N	I	I	S	L	L	N	V	F	T	P	Q	K	T	L	E	E	F	Q	D	V	Y	L	V	M	E	L	M	D	A	N	L	C	Q	V	I	Q	M	E	L	.	.	.	.	.	D	H	E	R	M	S	Y	L
Template Known Secondary structure								T	T	B				S					S			S	T	T	T												S								T	S			.	.	.	.	.
Template Predicted Secondary structure																																																	.	.	.	.	.
Template SS confidence
		115	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.						.	.	.	.	.	.	.	.
		345	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	A	Q	I	A	E	G	M	A	F	I	E	E	Q	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	D	T	L	S	C	K	I	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	E	G	A	K	F	P	I
Query Conservation
Alig confidence																																																				.	.	.	.	.	.	.	.	.	.
Template Conservation																																																				.	.	.	.	.	.	.	.	.	.
Template Sequence		L	Y	Q	M	L	C	G	I	K	H	L	H	S	A	G	I	I	H	R	D	L	K	P	S	N	I	V	V	K	S	D	C	T	L	K	I	L	D	F	G	L	A	S	F	M	M	V	T	R	Y	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure															T	T								G	G	G					T	T	S																		T	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																				.	.	.	.	.	.	.	.	.	.
Template SS confidence
		170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.
		405	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.
Predicted Secondary structure																																																				.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																				.	.	.	.	.	.	.	.	.	.
Query Sequence		K	W	T	A	P	E	A	I	N	Y	G	T	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	I	V	T	H	G	R	I	P	Y	P	G	M	T	N	P	E	V	I	Q	N	L	E	.	.	.	.	.	.	.	.	.	.
Query Conservation																																																				.	.	.	.	.	.	.	.	.	.
Alig confidence		.																															.																			.	.	.	.	.	.	.	.	.	.
Template Conservation		.																															.
Template Sequence		.	Y	R	A	P	E	V	I	L	G	M	G	Y	K	E	N	V	D	I	W	S	V	G	C	I	M	G	E	M	V	R	.	H	K	I	L	F	P	G	R	D	Y	I	D	Q	W	N	K	V	I	E	Q	L	G	T	P	C	P	E	F
Template Known Secondary structure		.	T							T	T					T	T																.	S	S		S	S			S	S														S
Template Predicted Secondary structure		.																															.
Template SS confidence
			229	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.		.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.
																																	455	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	R	G	Y	R	M	V	R	P	D	N	C	P	E	E	L	Y	H	L	M	M	L	C	W	K	E	R	P	E	D
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		M	K	K	L	Q	P	T	V	R	N	Y	V	E	N	R	P	K	Y	A	G	L	T	F	P	K	L	F	P	D	S	L	F	P	A	D	S	E	H	N	K	L	K	A	S	Q	A	R	D	L	L	S	K	M	L	V	I	D	P	A	K
Template Known Secondary structure			T	T	S									T	T	S												S		G	G	G	S			S	S																		S		S	S	T	T	T
Template Predicted Secondary structure
Template SS confidence
		287	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.
		484	.	.	.	.	.	490	.	.			.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.
Predicted Secondary structure											.	.
Query SS confidence											.	.
Query Sequence		R	P	T	F	D	Y	L	R	S	.	.	V	L	D	D	F	F	T	A	T	E	G	Q	Y	Q	P	Q	P
Query Conservation											.	.
Alig confidence											.	.
Template Conservation
Template Sequence		R	I	S	V	D	D	A	L	Q	H	P	Y	I	N	V	W	Y	D	P	A	E	V	E	A	P	P	E	H
Template Known Secondary structure		S								T	S	T	T	T	G	G	G							S
Template Predicted Secondary structure
Template SS confidence
		347	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D