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Job DescriptionP06240
Confidence100.00%DateWed Jul 10 14:01:50 BST 2013
Rank222Aligned Residues230
% Identity23%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   238.240.........250.........260...... ...270.........280.........290......
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Query Sequence  WEVPRETLKLVERLGAGQFGEVWMGYYNG. HTKVAVKSLKQGSMSPDAFLAEANLMKQLQ
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Template Sequence  KQVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILK. . . . . . KEVIVANRVLQNSR
Template Known Secondary structure  T


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   112.......120.........130.........140.........150. ........160.....
 
   297..300......... 310.........320.........330.........340.........350.....
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Query Sequence  HPRLVRLYAVVTQ. EPIYIITEYMENGSLVDFLKTPSGIKLNVNKLLDMAAQIAEGMAFI
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Template Sequence  HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRER. . VFSEDRARFYGAEIVSALDYL
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   207..210.........220.........230.........240... ......250.........260....
 
   356.. .360.........370.........380.........390.........400.........410....
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Query Sequence  EEQ. NYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINY
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Template Sequence  HSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKE. . . . . . . . . . . . . . . PEYLAPEVLED
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   265....270.........280.........290........ .300.........
 
   415....420.........430.........440.........450.........460.........470....
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Query Sequence  GTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYHLMM
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Template Sequence  NDYGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLFELILMEE. IRFPRTLGPEAKSLLS
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   324.....330.........340.... .....350.........360..... ....370.........380.
 
   475....480.... .....490..
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Query Sequence  LCWKERPEDR. . . . . PTFDYLRS
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Template Sequence  GLLKKDPKQRLGGGSEDAKEIMQ
Template Known Secondary structure  T
SSTTTSTT
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   382.......390.........400....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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