Job Description P06240 Confidence 100.00% Date Wed Jul 10 14:01:50 BST 2013 Rank 85 Aligned Residues 262 % Identity 37% Template c3lxnA_ PDB info PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 Resolution 2.50 Å

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		236	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.						.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.			.	.	.	.	.	.
Predicted Secondary structure																																.	.	.	.	.																		.	.
Query SS confidence																																.	.	.	.	.																		.	.
Query Sequence		D	E	W	E	V	P	R	E	T	L	K	L	V	E	R	L	G	A	G	Q	F	G	E	V	W	M	G	Y	Y	N	.	.	.	.	.	G	H	T	K	V	A	V	K	S	L	K	Q	G	S	M	S	P	.	.	D	A	F	L	A	E
Query Conservation																																.	.	.	.	.																		.	.
Alig confidence																																.	.	.	.	.																		.	.
Template Conservation
Template Sequence		D	P	T	V	F	H	K	R	Y	L	K	K	I	R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	K	A	D	A	G	P	Q	H	R	S	G	W	K	Q	E
Template Known Secondary structure								G	G	G											S	S										T	T	S	S	S												S	S
Template Predicted Secondary structure
Template SS confidence
		888	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.
		289	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.				.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.
Predicted Secondary structure																									.	.	.
Query SS confidence																									.	.	.
Query Sequence		A	N	L	M	K	Q	L	Q	H	P	R	L	V	R	L	Y	A	V	V	T	Q	E	P	.	.	.	I	Y	I	I	T	E	Y	M	E	N	G	S	L	V	D	F	L	K	T	P	S	G	I	K	L	N	V	N	K	L	L	D	M	A
Query Conservation																									.	.	.
Alig confidence																									.	.	.																						.	.	.
Template Conservation																																																	.	.	.
Template Sequence		I	D	I	L	R	T	L	Y	H	E	H	I	I	K	Y	K	G	C	C	E	D	A	G	A	A	S	L	Q	L	V	M	E	Y	V	P	L	G	S	L	R	D	Y	L	P	R	H	S	.	.	.	I	G	L	A	Q	L	L	L	F	A
Template Known Secondary structure											T	T	B										T	T	T	T										T	T		B					G	G	G	S		.	.	.
Template Predicted Secondary structure																																																	.	.	.
Template SS confidence
		948	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.				.	.	.	.	.	1000	.	.	.	.
		346	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	Q	I	A	E	G	M	A	F	I	E	E	Q	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	D	T	L	S	C	K	I	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	E	G	A	K	F	P	I	K
Query Conservation
Alig confidence																																																											.	.
Template Conservation																																																											.	.
Template Sequence		Q	Q	I	C	E	G	M	A	Y	L	H	A	Q	H	Y	I	H	R	D	L	A	A	R	N	V	L	L	D	N	D	R	L	V	K	I	G	D	F	G	L	A	K	A	V	P	E	G	H	E	Y	R	V	G	D	S	P	V	.	.	F
Template Known Secondary structure														T	T				S			S	G	G	G						T	T								T	T						T	T				B						G	.	.	G
Template Predicted Secondary structure																																																											.	.
Template SS confidence
		1005	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.			.
		406	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.																.	.	.	.	.	.	.	450
Predicted Secondary structure																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		W	T	A	P	E	A	I	N	Y	G	T	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	I	V	T	H	G	R	I	P	Y	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	M	T	N	P	E	V	I
Query Conservation																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																.							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																.
Template Sequence		W	Y	A	P	E	C	L	K	E	Y	K	F	Y	Y	A	S	D	V	W	S	F	G	V	T	L	Y	E	L	L	T	.	H	C	D	S	S	Q	S	P	P	T	K	F	L	E	L	I	G	I	A	Q	G	Q	M	T	V	L	R	L	T
Template Known Secondary structure		G								S		B																			T	.	T	T		G	G	G	S											S	T	T	G	G	G
Template Predicted Secondary structure																																.
Template SS confidence
		1067	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.		.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.
		451	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	N	L	E	R	G	Y	R	M	V	R	P	D	N	C	P	E	E	L	Y	H	L	M	M	L	C	W	K	E	R	P	E	D	R	P	T	F	D	Y	L	R	S	V	L	D	D	F	F	T	A	T	E	G
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	L	L	E	R	G	E	R	L	P	R	P	D	K	C	P	A	E	V	Y	H	L	M	K	N	C	W	E	T	E	A	S	F	R	P	T	F	E	N	L	I	P	I	L	K	T	V	H	E	K	Y	Q	G
Template Known Secondary structure						T	T							T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1126	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D