Job Description P06240 Confidence 100.00% Date Wed Jul 10 14:01:50 BST 2013 Rank 47 Aligned Residues 256 % Identity 37% Template c3lxkA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 Resolution 2.00 Å

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		240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.						.	.	.	.	.	270	.	.	.	.	.	.	.	.	.		280	.	.	.	.	.	.	.	.	.	290	.	.	.
Predicted Secondary structure																											.	.	.	.	.																.
Query SS confidence																											.	.	.	.	.																.
Query Sequence		V	P	R	E	T	L	K	L	V	E	R	L	G	A	G	Q	F	G	E	V	W	M	G	Y	Y	.	.	.	.	.	N	G	H	T	K	V	A	V	K	S	L	K	Q	G	S	.	M	S	P	D	A	F	L	A	E	A	N	L	M	K
Query Conservation																											.	.	.	.	.																.
Alig confidence																											.	.	.	.	.																.
Template Conservation
Template Sequence		F	E	E	R	H	L	K	Y	I	S	Q	L	G	K	G	N	F	G	S	V	E	L	C	R	Y	D	P	L	G	D	N	T	G	A	L	V	A	V	K	Q	L	Q	H	S	G	P	D	Q	Q	R	D	F	Q	R	E	I	Q	I	L	K
Template Known Secondary structure				G	G	G											T	T										T	T	S	S	S		S									S	S
Template Predicted Secondary structure
Template SS confidence
		817	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.
		294	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.				310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Predicted Secondary structure																		.	.	.
Query SS confidence																		.	.	.
Query Sequence		Q	L	Q	H	P	R	L	V	R	L	Y	A	V	V	T	Q	.	.	.	E	P	I	Y	I	I	T	E	Y	M	E	N	G	S	L	V	D	F	L	K	T	P	S	G	I	K	L	N	V	N	K	L	L	D	M	A	A	Q	I	A	E
Query Conservation																		.	.	.
Alig confidence																		.	.	.																								.
Template Conservation																																												.
Template Sequence		A	L	H	S	D	F	I	V	K	Y	R	G	V	S	Y	G	P	G	R	Q	S	L	R	L	V	M	E	Y	L	P	S	G	C	L	R	D	F	L	Q	R	H	R	.	A	R	L	D	A	S	R	L	L	L	Y	S	S	Q	I	C	K
Template Known Secondary structure		T				T	T	B									S	S	S	S											T	T		B									G	.	G	G
Template Predicted Secondary structure																																												.
Template SS confidence
		877	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.		.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.
		351	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390			.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.
Predicted Secondary structure																																										.	.
Query SS confidence																																										.	.
Query Sequence		G	M	A	F	I	E	E	Q	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	D	T	L	S	C	K	I	A	D	F	G	L	A	R	L	I	E	.	.	D	N	E	Y	T	A	R	E	G	A	K	F	P	I	K	W	T	A
Query Conservation																																										.	.
Alig confidence																																										.	.
Template Conservation
Template Sequence		G	M	E	Y	L	G	S	R	R	C	V	H	R	D	L	A	A	R	N	I	L	V	E	S	E	A	H	V	K	I	A	D	F	G	L	A	K	L	L	P	L	D	K	D	Y	Y	V	V	R	E	P	G	Q	S	P	I	F	W	Y	A
Template Known Secondary structure									T	T				S			S	G	G	G						T	T								T	T						T	T		S					S	S				S		G	G	G
Template Predicted Secondary structure
Template SS confidence
		936	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.
		409	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.											.	.	.	.	.	.	450	.	.	.	.	.	.	.	.
Predicted Secondary structure																																					.	.	.	.	.	.	.	.	.	.
Query SS confidence																																					.	.	.	.	.	.	.	.	.	.
Query Sequence		P	E	A	I	N	Y	G	T	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	I	V	T	H	G	R	I	P	Y	P	G	.	.	.	.	.	.	.	.	.	.	M	T	N	P	E	V	I	Q	N	L	E	R	G	Y	R
Query Conservation																																					.	.	.	.	.	.	.	.	.	.
Alig confidence																													.								.	.	.	.	.	.	.	.	.	.
Template Conservation																													.
Template Sequence		P	E	S	L	S	D	N	I	F	S	R	Q	S	D	V	W	S	F	G	V	V	L	Y	E	L	F	T	.	Y	C	D	K	S	C	S	P	S	A	E	F	L	R	M	M	V	P	A	L	S	R	L	L	E	L	L	E	E	G	Q	R
Template Known Secondary structure																												T	.	T	T		G	G	G	S																						T	T
Template Predicted Secondary structure																													.
Template SS confidence
		996	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.		.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.
		459	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	V	R	P	D	N	C	P	E	E	L	Y	H	L	M	M	L	C	W	K	E	R	P	E	D	R	P	T	F	D	Y	L	R	S	V	L	D	D	F
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	P	A	P	P	A	C	P	A	E	V	H	E	L	M	K	L	C	W	A	P	S	P	Q	D	R	P	S	F	S	A	L	G	P	Q	L	D	M	L
Template Known Secondary structure						T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D