Job Description P06240 Confidence 100.00% Date Wed Jul 10 14:01:50 BST 2013 Rank 227 Aligned Residues 268 % Identity 34% Template c2xbaA_ PDB info PDB header:transferase Chain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of human anaplastic lymphoma kinase in complex2 with pha-e429 Resolution 1.95 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		235	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.					.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.			.	.	280	.	.	.	.	.	.	.	.
Predicted Secondary structure																								.	.	.	.																						.	.
Query SS confidence																								.	.	.	.																						.	.
Query Sequence		E	D	E	W	E	V	P	R	E	T	L	K	L	V	E	R	L	G	A	G	Q	F	.	.	.	.	G	E	V	W	M	G	Y	Y	N	G	H	T	K	V	A	V	K	S	L	K	Q	.	.	G	S	M	S	P	D	A	F	L	A	E
Query Conservation																								.	.	.	.																						.	.
Alig confidence																								.	.	.	.											.											.	.
Template Conservation																																						.
Template Sequence		N	Y	C	F	A	G	K	T	S	S	I	S	D	L	K	E	V	P	R	K	N	I	T	L	I	R	G	L	V	Y	E	G	Q	V	S	P	.	L	Q	V	A	V	K	T	L	P	E	V	C	S	E	Q	D	E	L	D	F	L	M	E
Template Known Secondary structure						T	T					G	G	G	S		B			G	G	G																.										S	S
Template Predicted Secondary structure																																						.
Template SS confidence
		1095	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130		.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.
		289	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.		310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330						.	.	.	.	.	.	.	.	.	340	.	.
Predicted Secondary structure																							.																						.	.	.	.	.
Query SS confidence																							.																						.	.	.	.	.
Query Sequence		A	N	L	M	K	Q	L	Q	H	P	R	L	V	R	L	Y	A	V	V	T	Q	.	E	P	I	Y	I	I	T	E	Y	M	E	N	G	S	L	V	D	F	L	K	T	.	.	.	.	.	P	S	G	I	K	L	N	V	N	K	L	L
Query Conservation																							.																						.	.	.	.	.
Alig confidence																							.																						.	.	.	.	.
Template Conservation
Template Sequence		A	L	I	I	S	K	F	N	H	Q	N	I	V	R	C	I	G	V	S	L	Q	S	L	P	R	F	I	L	L	E	L	M	A	G	G	D	L	K	S	F	L	R	E	T	R	P	R	P	S	Q	P	S	S	L	A	M	L	D	L	L
Template Known Secondary structure											T	T	B									S	S	S	S									T	T											S		B	T	T	B	T	T	S
Template Predicted Secondary structure
Template SS confidence
		1168	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.
		343	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	M	A	A	Q	I	A	E	G	M	A	F	I	E	E	Q	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	D	T	L	S	C	K	I	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	E	G	A	K	F
Query Conservation
Alig confidence																																																						.	.	.	.	.	.
Template Conservation																																																						.	.	.	.	.	.
Template Sequence		H	V	A	R	D	I	A	C	G	C	Q	Y	L	E	E	N	H	F	I	H	R	D	I	A	A	R	N	C	L	L	T	C	P	G	P	G	R	V	A	K	I	G	D	F	G	M	A	R	D	I	Y	A	.	.	.	.	.	.	M	L
Template Known Secondary structure																	T	T				S				G	G	G				S		S	S	T	T																	.	.	.	.	.	.		S
Template Predicted Secondary structure																																																						.	.	.	.	.	.
Template SS confidence
		1228	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260	.	.	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.							1280	.
		403	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	I	K	W	T	A	P	E	A	I	N	Y	G	T	F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	I	V	T	H	G	R	I	P	Y	P	G	M	T	N	P	E	V	I	Q	N	L	E	R	G	Y	R	M	V	R	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	V	K	W	M	P	P	E	A	F	M	E	G	I	F	T	S	K	T	D	T	W	S	F	G	V	L	L	W	E	I	F	S	L	G	Y	M	P	Y	P	S	K	S	N	Q	E	V	L	E	F	V	T	S	G	G	R	M	D	P	P
Template Known Secondary structure			G	G	G								T																					T	T	S			S	S	T	T												T	T
Template Predicted Secondary structure
Template SS confidence
		1292	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.	.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330	.	.	.	.	.	.	.	.	.	1340	.	.	.	.	.	.	.	.	.	1350	.
		463	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	N	C	P	E	E	L	Y	H	L	M	M	L	C	W	K	E	R	P	E	D	R	P	T	F	D	Y	L	R	S	V	L	D	D	F	F	T	A	T	E	G	Q	Y	Q	P	Q	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	N	C	P	G	P	V	Y	R	I	M	T	Q	C	W	Q	H	Q	P	E	D	R	P	N	F	A	I	I	L	E	R	I	E	Y	C	T	Q	D	P	D	V	I	N	T	A	L	P
Template Known Secondary structure		T	T													T		S	S	G	G	G	S																					T
Template Predicted Secondary structure
Template SS confidence
		1352	.	.	.	.	.	.	.	1360	.	.	.	.	.	.	.	.	.	1370	.	.	.	.	.	.	.	.	.	1380	.	.	.	.	.	.	.	.	.	1390	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D