Job Description P06240 Confidence 100.00% Date Wed Jul 10 14:01:50 BST 2013 Rank 132 Aligned Residues 253 % Identity 22% Template c2r7bA_ PDB info PDB header:signaling protein, transferase Chain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor Resolution 2.70 Å

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		243	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.		.	.	.	.	.	270	.	.	.	.	.	.					.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.
Predicted Secondary structure																								.													.	.	.	.
Query SS confidence																								.													.	.	.	.
Query Sequence		E	T	L	K	L	V	E	R	L	G	A	G	Q	F	G	E	V	W	M	G	Y	Y	.	N	G	H	T	K	V	A	V	K	S	L	K	.	.	.	.	Q	G	S	M	S	P	D	A	F	L	A	E	A	N	L	M	K	Q	L	Q	H
Query Conservation																								.													.	.	.	.
Alig confidence																								.													.	.	.	.
Template Conservation
Template Sequence		E	D	F	K	F	G	K	I	L	G	E	G	S	F	S	T	V	V	L	A	R	E	L	A	T	S	R	E	Y	A	I	K	I	L	E	K	R	H	I	I	K	E	N	K	V	P	Y	V	T	R	E	R	D	V	M	S	R	L	D	H
Template Known Secondary structure		G	G											S	S									T	T	T																	T	T														T
Template Predicted Secondary structure
Template SS confidence
		80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.
		298	.	300	.	.	.	.	.	.	.	.	.		310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.
Predicted Secondary structure														.
Query SS confidence														.
Query Sequence		P	R	L	V	R	L	Y	A	V	V	T	Q	.	E	P	I	Y	I	I	T	E	Y	M	E	N	G	S	L	V	D	F	L	K	T	P	S	G	I	K	L	N	V	N	K	L	L	D	M	A	A	Q	I	A	E	G	M	A	F	I	E
Query Conservation														.
Alig confidence														.																								.	.
Template Conservation																																						.	.
Template Sequence		P	F	F	V	K	L	Y	F	T	F	Q	D	D	E	K	L	Y	F	G	L	S	Y	A	K	N	G	E	L	L	K	Y	I	R	K	I	G	.	.	S	F	D	E	T	C	T	R	F	Y	T	A	E	I	V	S	A	L	E	Y	L	H
Template Known Secondary structure		T	T	B										S	S										T	T		B								S	S	.	.	S
Template Predicted Secondary structure																																						.	.
Template SS confidence
		140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.			.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.
		357	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	Q	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	D	T	L	S	C	K	I	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	E	G	A	K	F	P	I	K	W	T	A	P	E	A	I	N	Y	G	T
Query Conservation
Alig confidence																																									.	.	.	.	.	.	.	.	.	.
Template Conservation																																									.	.	.	.	.	.	.	.	.	.
Template Sequence		G	K	G	I	I	H	R	D	L	K	P	E	N	I	L	L	N	E	D	M	H	I	Q	I	T	D	F	G	T	A	K	V	L	F	V	G	T	A	Q	.	.	.	.	.	.	.	.	.	.	Y	V	S	P	E	L	L	T	E	K	S
Template Known Secondary structure			T	T								T	T	T					T	T	S								T	T									G	G	.	.	.	.	.	.	.	.	.	.	G								S	S
Template Predicted Secondary structure																																									.	.	.	.	.	.	.	.	.	.
Template SS confidence
		198	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.											.	.	.	240	.	.	.	.	.	.	.
		417	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	T	I	K	S	D	V	W	S	F	G	I	L	L	T	E	I	V	T	H	G	R	I	P	Y	P	G	M	T	N	P	E	V	I	Q	N	L	E	R	G	Y	R	M	V	R	P	D	N	C	P	E	E	L	Y	H	L	M	M	L	C
Query Conservation
Alig confidence																					.																						.
Template Conservation																					.																						.
Template Sequence		A	C	K	S	S	D	L	W	A	L	G	C	I	I	Y	Q	L	V	A	.	G	L	P	P	F	R	A	G	N	E	Y	L	I	F	Q	K	I	I	K	L	E	.	Y	D	F	P	E	K	F	F	P	K	A	R	D	L	V	E	K	L
Template Known Secondary structure																					.	S	S		S				S	S											T		.					S	S	S										T	T
Template Predicted Secondary structure																					.																						.
Template SS confidence
		259	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.		.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.		.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.
		477	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.									.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																		.	.	.	.	.	.	.	.
Query SS confidence																		.	.	.	.	.	.	.	.
Query Sequence		W	K	E	R	P	E	D	R	P	T	F	D	Y	L	R	S	.	.	.	.	.	.	.	.	V	L	D	D	F	F	T	A	T	E	G	Q	Y	Q	P	Q	P
Query Conservation																		.	.	.	.	.	.	.	.
Alig confidence																		.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		L	V	L	D	A	T	K	R	L	G	C	E	E	M	E	G	Y	G	P	L	K	A	H	P	F	F	E	S	V	T	W	E	N	L	H	Q	Q	T	P	P	K
Template Known Secondary structure		S		S	S	T	T	S	S	T	T	S	G	G	G	T	T							S	G	G	G	T	T			G	G	G	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		317	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D