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Job DescriptionP06240
Confidence100.00%DateWed Jul 10 14:01:50 BST 2013
Rank7Aligned Residues370
% Identity34%Templatec2ozoA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70
Resolution2.60 Å
Model Dimensions (Å)X:67.461 Y:84.134 Z:44.049

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   119120.........130.........140.........150.........160.........170........
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Query Sequence  ANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVV
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Template Sequence  PDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVR. . . . . F
Template Known Secondary structure 

TTSS
TTB
BS

TTT

TT
TTBTT
TT.....
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   2.......10.........20.........30.........40.........50..... .
 
   179180.........190.........200.........210.........220.........230....
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Query Sequence  KHYKIRNLDNGGFYISPRITFPGLHDLVRHYTNASDGLCTKLSRPCQTQKPQKPWW. . . .
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Template Sequence  HHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFD
Template Known Secondary structure 
TTS
TTS

BSSTS

TTSSS


SB



TT


B

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   57..60.........70.........80.........90.........100.........110......
 
  
Predicted Secondary structure  ............................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  CLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERK
Template Known Secondary structure 


TTS
TTTSTTB
TT

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   117..120.........130.........140.........150.........160.........170......
 
  
Predicted Secondary structure  ............................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  LYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLV
Template Known Secondary structure  SSS


TT

SSTTTT
TT


TTS
SS
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   177..180.........190.........200.........210.........220.........230......
 
   235....240.........250......
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EDEWEVPRETLKLVERLGAGQF
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Template Sequence  EYLKLKADGLIYCLKEACPNMDTSVFESPFSDPEELKDKKLFLKRDNLLIADIELGCGNF
Template Known Secondary structure 

TT
SS


SB






S
SSSSS
S
SS



SB

TTS
SS
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   237..240.........250.........260.........270.........280.........290......
 
   257..260........ .270.........280 .........290.........300.........310.
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Query Sequence  GEVWMGYYNGHT. . . KVAVKSLKQGSM. . SPDAFLAEANLMKQLQHPRLVRLYAVVTQEP
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Template Sequence  GSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVCQAEA
Template Known Secondary structure  S
SS





SSTTTT


TTB

SSS
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   350.........360.........370.........380.........390.........400.........
 
   312.......320.........330.........340.........350.........360.........370.
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Query Sequence  IYIITEYMENGSLVDFLKTPSGIKLNVNKLLDMAAQIAEGMAFIEEQNYIHRDLRAANIL
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Template Sequence  LMLVMEMAGGGPLHKFLVGKREE. IPVSNVAELLHQVSMGMKYLEEKNFVHRNLAARNVL
Template Known Secondary structure 

TT
BTT
TTT.S
TT


S

SGGG
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   410.........420.........430.. .......440.........450.........460........
 
   372.......380.........390.........400.........410.........420.........430.
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Query Sequence  VSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLT
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Template Sequence  LVNRHYAKISDFGLSKALG. . . . . . . . . . . . PLKWYAPECINFRKFSSRSDVWSYGVTMW
Template Known Secondary structure  TT


STTTT

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TTS




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   469470.........480....... ..490.........500.........510......
 
   432.......440.........450.........460.........470.........480.........490.
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Query Sequence  EIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYHLMMLCWKERPEDRPTFDYLR
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Template Conservation 
  
 
  
            
        
   
     

  
    
  

    
 
Template Sequence  EALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVE
Template Known Secondary structure  TTS

TTTT

STT





TT

TT
SSTTTS

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   531........540.........550.........560.........570.........580.........590
 
   492.......500......
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Query Sequence  SVLDDFFTATEGQYQ
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Template Conservation    
            
Template Sequence  QRMRACYYSLASKVE
Template Known Secondary structure  S
S

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   591........600.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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