Job Description P06240 Confidence 100.00% Date Wed Jul 10 14:01:50 BST 2013 Rank 5 Aligned Residues 431 % Identity 71% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å Model Dimensions (Å) X:63.930 Y:72.543 Z:50.340

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		65	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	V	I	A	L	H	S	Y	E	P	S	H	D	G	D	L	G	F	E	K	G	E	Q	L	R	I	L	E	Q	S	G	E	W	W	K	A	Q	S	L	T	T	G	Q	E	G	F	I	P	F	N	F	V	A	K	A	N	S	L	E	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		I	V	V	A	L	Y	D	Y	E	A	I	H	H	E	D	L	S	F	Q	K	G	D	Q	M	V	V	L	E	E	S	G	E	W	W	K	A	R	S	L	A	T	R	K	E	G	Y	I	P	S	N	Y	V	A	R	V	D	S	L	E	T
Template Known Secondary structure						S	S		B				S	S	S	B			B		T	T										T	T							T	T	T								G	G	G				T	T	S	G	G	G
Template Predicted Secondary structure
Template SS confidence
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
		125	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	P	W	F	F	K	N	L	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	T	H	G	S	F	L	I	R	E	S	E	S	T	A	G	S	F	S	L	S	V	R	D	F	D	Q	N	Q	G	E	V	V	K	H	Y	K	I	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	E	W	F	F	K	G	I	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	Y	S	L	S	V	R	D	Y	D	P	R	Q	G	D	T	V	K	H	Y	K	I	R
Template Known Secondary structure		S	T	T			T	T											T	S	T	T			T	T								S	S	S	T	T											T	T	T										B
Template Predicted Secondary structure
Template SS confidence
		121	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
		185	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	L	D	N	G	G	F	Y	I	S	P	R	I	T	F	P	G	L	H	D	L	V	R	H	Y	T	N	A	S	D	G	L	C	T	K	L	S	R	P	C	Q	T	Q	K	P	Q	K	P	W	W	E	D	E	W	E	V	P	R	E	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		T	L	D	N	G	G	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L	C	Q	K	L	S	V	P	C	M	S	S	K	P	Q	K	P	W	E	K	D	A	W	E	I	P	R	E	S
Template Known Secondary structure				S	T	T				S	S	T	T	S			S	S								T	T	S	S		S	S		S	S				S	B												T	T		S	B			G	G	G
Template Predicted Secondary structure
Template SS confidence
		181	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
		245	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	K	L	V	E	R	L	G	A	G	Q	F	G	E	V	W	M	G	Y	Y	N	G	H	T	K	V	A	V	K	S	L	K	Q	G	S	M	S	P	D	A	F	L	A	E	A	N	L	M	K	Q	L	Q	H	P	R	L	V	R	L	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	K	H	T	K	V	A	V	K	T	M	K	P	G	S	M	S	V	E	A	F	L	A	E	A	N	V	M	K	T	L	Q	H	D	K	L	V	K	L	H
Template Known Secondary structure												T	T									T	T	T												S	S														T				T	T	B
Template Predicted Secondary structure
Template SS confidence
		241	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
		305	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	V	V	T	Q	E	P	I	Y	I	I	T	E	Y	M	E	N	G	S	L	V	D	F	L	K	T	P	S	G	I	K	L	N	V	N	K	L	L	D	M	A	A	Q	I	A	E	G	M	A	F	I	E	E	Q	N	Y	I	H	R	D
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	V	V	T	K	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E	Q	R	N	Y	I	H	R	D
Template Known Secondary structure						S	S	S									T	T		B							S	T	T	G	G	G																							T	T				S
Template Predicted Secondary structure
Template SS confidence
		301	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
		365	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	R	A	A	N	I	L	V	S	D	T	L	S	C	K	I	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	E	G	A	K	F	P	I	K	W	T	A	P	E	A	I	N	Y	G	T	F	T	I	K	S	D	V	W
Query Conservation
Alig confidence																									.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																									.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	R	A	A	N	I	L	V	S	A	S	L	V	C	K	I	A	D	F	G	L	A	R	.	.	.	.	.	.	.	.	.	.	.	.	.	V	I	P	I	K	W	T	A	P	E	A	I	N	F	G	S	F	T	I	K	S	D	V	W
Template Known Secondary structure			S	G	G	G					T	T								T	T	G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	T			G	G	G	S
Template Predicted Secondary structure																									.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		361	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.														.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.
		425	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	F	G	I	L	L	T	E	I	V	T	H	G	R	I	P	Y	P	G	M	T	N	P	E	V	I	Q	N	L	E	R	G	Y	R	M	V	R	P	D	N	C	P	E	E	L	Y	H	L	M	M	L	C	W	K	E	R	P	E	D	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P	E	V	I	R	A	L	E	R	G	Y	R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	M	M	R	C	W	K	N	R	P	E	E	R
Template Known Secondary structure												T	T	T			S	S	T	T												T	T							T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		421	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
		485	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	T	F	D	Y	L	R	S	V	L	D	D	F	F	T	A	T	E	G	Q	Y	Q	P	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A	T	E	S	Q	E	E	I	P
Template Known Secondary structure													T	T	T	S		G	G	G
Template Predicted Secondary structure
Template SS confidence
		481	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.