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Job DescriptionP16277
Confidence100.00%DateTue Jul 30 13:14:40 BST 2013
Rank35Aligned Residues255
% Identity42%Templatec4ebwA_
PDB info PDB header:transferase/transferase inhibitorChain: A: PDB Molecule:focal adhesion kinase 1; PDBTitle: structure of focal adhesion kinase catalytic domain in complex with2 novel allosteric inhibitor
Resolution2.65 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   224.....230.........240.........250........ .260.........270 .........
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Query Sequence  AQDEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNNM. . KVAIKTLKEGTM. . SPEAFLGEA
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Template Sequence  STRDYEIQRERIELGRCIGEGQFGDVHQGIYMSNPALAVAIKTCKNCTSDSVREKFLQEA
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GGGB

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   411........420.........430.........440.........450.........460.........470
 
   280.........290.........300.........310.........320.........330.........
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Query Sequence  NVMKTLQHERLVRLYAVVTREPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQVA
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Template Sequence  LTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYS. LDLASLILYAYQLS
Template Known Secondary structure  T


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TT
BTTTT.

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   473......480.........490.........500.........510....... ..520.........530.
 
   340.........350.........360.........370.........380.........390.........
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Query Sequence  EGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPE
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Template Sequence  TALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLKL. . . . . . . . . . . . . . PIKWMAPE
Template Known Secondary structure  TT




GGG
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   532.......540.........550.........560......... 570.......
 
   400.........410.........420.........430.........440.........450.........
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Query Sequence  AIHFGVFTIKADVWSFGVLLMEIVTYGRVPYPGMSNPEVIRSLEHGYRMPCPETCPPELY
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Template Sequence  SINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTL.
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TTT

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   593......600.........610.........620.........630.........640.........650.
 
   460.........470.........480.........490....
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Query Sequence  NDIITECWRGRPEERPTFEFLQSVLEDFYTATEGQ
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Template Sequence  YSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQ
Template Known Secondary structure  T
SSTTTS

T
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   652.......660.........670.........680......
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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