|   |   |
233 | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | S | L | K | L | V | R | K | L | G | S | G | Q | F | G | E | V | W | M | G | Y | Y | K | N | N | M | K | V | A | I | K | T | L | K | E | G | T | M | S | P | E | A | F | L | G | E | A | N | V | M | K | T | L | Q | H | E | R | L | V | R |
| Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |
|   |
|
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|
|   |   |   |   | . | . | . |   |
|
|
|
|   |
|   |   | . | . | . |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|   |
|
|
|   |
| Template Sequence |   |
I | P | F | T | L | G | R | M | L | G | K | G | E | F | G | S | V | R | E | A | Q | L | V | . |
. |
. |
K | V | A | V | K | M | L | S | S | . |
. |
. |
D | I | E | E | F | L | R | E | A | A | C | M | K | E | F | D | H | P | H | V | A | K |
| Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
| . | . | . |  |  |  |  |  |  |
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| T | T | B |
|
|
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  | . | . | . |  |  |  |  |  |  |  |
|  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
503 | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | |
|
|
. | . | . | . | 530 | . | . | . | . | |
|
|
. | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . |
|   |
|   |   |
293 | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | |
320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  | . |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | Y | A | V | V | T | R | E | P | I | Y | I | V | T | E | Y | M | A | R | G | C | L | L | D | F | L | K | . |
T | D | E | G | S | R | L | S | L | P | R | L | I | D | M | S | A | Q | V | A | E | G | M | A | Y | I | E | R | M | N | S | I |
| Query Conservation |   |
|   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
L | V | G | V | S | L | R | S | I | P | M | V | I | L | P | F | M | K | H | G | D | L | H | A | F | L | L | A | S | R | I | P | F | N | L | P | L | Q | T | L | V | R | F | M | V | D | I | A | C | G | M | E | Y | L | S | S | R | N | F | I |
| Template Known Secondary structure |   |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |
|
| T | T |
| B |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| Template Predicted Secondary structure |   |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
573 | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . |
|   |
|   |   |
352 | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
H | R | D | L | R | A | A | N | I | L | V | S | E | T | L | C | C | K | I | A | D | F | G | L | A | R | I | I | D | S | E | Y | T | A | Q | E | G | A | K | F | P | I | K | W | T | A | P | E | A | I | H | F | G | V | F | T | I | K | A | D |
| Query Conservation |   |
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |
|   |
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
| Template Sequence |   |
H | R | D | L | A | A | R | N | C | M | L | A | E | D | M | T | V | C | V | A | D | F | G | L | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | V | K | W | L | A | L | E | S | L | A | D | N | L | Y | T | V | H | S | D |
| Template Known Secondary structure |   |
| S |
|
| S | G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| G | G | G |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
643 | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . |
|   |
|   |   |
412 | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
V | W | S | F | G | V | L | L | M | E | I | V | T | Y | G | R | V | P | Y | P | G | M | S | N | P | E | V | I | R | S | L | E | H | G | Y | R | M | P | C | P | E | T | C | P | P | E | L | Y | N | D | I | I | T | E | C | W | R | G | R | P |
| Query Conservation |   |
|
|
|   |
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |
|
|
|   |   |
|   |
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |
|
|   |   |
|
|   |   |
|
|
| Template Sequence |   |
V | W | A | F | G | V | T | M | W | E | I | M | T | R | G | Q | T | P | Y | A | G | I | E | N | A | E | I | Y | N | Y | L | I | G | G | N | R | L | K | Q | P | P | E | C | M | E | E | V | . |
Y | D | L | M | Y | Q | C | W | S | A | D | P |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
| T | T | T | T |
|
| G | G | G |  |  |  |  |  |  | T | T |
|
|
|
|
|
| T | T |
|
|  |  |  | . |  |  |  |  |  |  | T | T |
| S | S | G |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . |  |  |  |  |  |  |  |
|
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
705 | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | |
. | . | . | . | . | . | . | . | 760 | . | . | . |
|   |
|   |   |
472 | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 |
| Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | E | R | P | T | F | E | F | L | Q | S | V | L | E | D | F | Y | T | A |
| Query Conservation |   |
  |   |
|
|
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|
|
|   |   |
|
|   |   |   |
|   |   |
|
|   |
|
| Template Sequence |   |
K | Q | R | P | S | F | T | C | L | R | M | E | L | E | N | I | L | G | H |
| Template Known Secondary structure |   |
G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| Template Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
764 | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . |
|   |