|   |   |
235 | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | |
. | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | |
|
|
|
. | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | K | L | V | R | K | L | G | S | G | Q | F | G | E | V | W | M | G | Y | Y | K | . |
N | N | M | K | V | A | I | K | T | L | K | E | G | T | M | S | P | E | A | . |
. |
. |
. |
F | L | G | E | A | N | V | M | K | T | L | Q | H | E | R |
| Query Conservation |   |
  |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   | . |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   | . | . | . | . |
|   |   |
|   |   |
|
|   |   |
|   |
|   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
L | K | L | V | E | P | L | R | V | G | D | R | S | V | V | F | L | V | R | D | V | E | R | L | E | D | F | A | L | K | V | F | T | M | G | A | E | N | S | R | S | E | L | E | R | L | H | E | A | T | F | A | A | A | R | L | L | G | R | L |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  |  |
|
| S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| B |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
234 | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . |
|   |
|   |   |
290 | . | . | . | . | . | . | . | . | . | 300 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
320 | . | . | . | . | . | . | . | . | . | 330 |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  | . | . | . | . | . |  |
|
|
|
|
|
|
|  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | V | R | L | Y | A | V | V | T | R | E | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | Y | I | V | T | E | Y | M | A | R | G | C | L | L | D | F | L | K | . |
. |
. |
. |
. |
T | D | E | G | S | R | L | S | L | P | R |
| Query Conservation |   |
|
|   |
|   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   | . |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
L | L | P | S | D | A | V | A | V | Q | S | Q | P | P | F | A | Q | L | S | P | G | Y | A | V | A | N | Y | L | L | L | M | P | A | A | . |
S | V | D | L | E | L | L | F | S | T | L | D | F | V | Y | V | F | R | G | D | E | G | I | L | A |
| Template Known Secondary structure |   |
|
|
|
|  |  |  |  |  | T | T | S |
| S | S | S | B |
| S |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
| . | S |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
304 | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | |
. | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . |
|   |
|   |   |
331 | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | I | D | M | S | A | Q | V | A | E | G | M | A | Y | I | E | R | M | N | S | I | H | R | D | L | R | A | A | N | I | L | V | S | E | T | L | C | C | K | I | A | D | F | G | L | A | R | I | I | D | S | E | Y | T | A | Q | E | G | A | K |
| Query Conservation |   |
  |   |   |
|   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |   |
|
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |
|   |   |
|
|   |
|
|
|   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |
| Template Sequence |   |
L | H | I | L | T | A | Q | L | I | R | L | A | A | N | L | Q | S | K | G | L | V | H | G | H | F | T | P | D | N | L | F | I | M | P | D | G | R | L | M | L | G | D | V | S | A | L | W | K | V | G | T | . |
. |
. |
R | G | P | A | S | S |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  | T | T |
| S | G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
| G | G | G |  |  |  | T | T |
| . | . | . |  |  |  | G | G | G |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . |
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
366 | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | |
|
|
. | . | . | 420 | . | . |
|   |
|   |   |
391 | . | . | . | . | . | . | . | . | 400 | . | |
|
. | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |
|
|  |  |  |  | . | . |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
F | P | I | K | W | T | A | P | E | A | I | . |
. |
H | F | G | V | F | T | I | K | A | D | V | W | S | F | G | V | L | L | M | E | I | V | T | Y | G | R | V | P | Y | P | G | M | S | N | P | E | V | I | R | S | L | E | H | G | Y | R | M |
| Query Conservation |   |
  |   |   |   |   |   |
|
|
|   |
| . | . |   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |
|   |
|
|
|   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
V | P | V | T | Y | A | P | R | E | F | L | N | A | S | T | A | T | F | T | H | A | L | N | A | W | Q | L | G | L | S | I | Y | R | V | W | C | . |
L | F | L | P | F | G | L | V | T | P | G | I | K | G | S | W | K | R | P | S | L | R | V |
| Template Known Secondary structure |   |
S |
| G | G | G |
|
|  |  |  |  | T |
| S |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | T | T | B |
|
| T | T |
| T | T |
|
|
| B |
|
| T | T | S |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
423 | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | |
. | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . |
|   |
|   |   |
449 | 450 | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . |
| Predicted Secondary structure |   |
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
P | C | P | E | . |
. |
. |
. |
. |
. |
. |
. |
T | C | P | P | E | L | Y | N | D | I | I | T | E | C | W | R | G | R | P | E | E | R | P | T | F | E | F | L | Q | S |
| Query Conservation |   |
  |   |
|   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|   |
|
|   |
|   |
|   |
| Template Sequence |   |
P | G | T | D | S | L | A | F | G | S | C | T | P | L | P | D | F | V | . |
K | T | L | I | G | R | F | L | N | F | D | R | R | R | R | L | L | P | L | E | A | M | E |
| Template Known Secondary structure |   |
|
|
|
| S |
|
|
| T | T | S | S |
|
|
|  |  |  | . |  |  |  |  |  |  |  | T |
| S | S | T | T | T |
|
|
|  |  |  |  | T | T |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
482 | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | |
500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . |
|   |