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Job DescriptionP16277
Confidence100.00%DateTue Jul 30 13:14:40 BST 2013
Rank227Aligned Residues230
% Identity23%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   228.230.........240.........250...... ...260.........270.........280......
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Query Sequence  WEIPRQSLKLVRKLGSGQFGEVWMGYYKN. NMKVAIKTLKEGTMSPEAFLGEANVMKTLQ
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Template Sequence  KQVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILK. . . . . . KEVIVANRVLQNSR
Template Known Secondary structure  T


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   112.......120.........130.........140.........150. ........160.....
 
   287..290.........300. ........310.........320.........330.........340.....
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Query Sequence  HERLVRLYAVVTREP. IYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQVAEGMAYI
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Template Sequence  HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRER. . VFSEDRARFYGAEIVSALDYL
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   207..210.........220.........230.........240... ......250.........260....
 
   346. ..350.........360.........370.........380.........390.........400....
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Query Sequence  ER. MNSIHRDLRAANILVSETLCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFG
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Template Sequence  HSEKNVVYRDLKLENLMLDKDGHIKITDFGL. . . . . . . . . . . . . . CKEPEYLAPEVLEDN
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GGG
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   265....270.........280.........290..... ....300.........310
 
   405....410.........420.........430.........440.........450.........460....
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Query Sequence  VFTIKADVWSFGVLLMEIVTYGRVPYPGMSNPEVIRSLEHGYRMPCPETCPPELYNDIIT
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Template Sequence  DYGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLFELILMEE. IRFPRTLGPEA. KSLLS
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   325....330.........340.... .....350.........360..... ....370...... ...380.
 
   465....470.... .....480..
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Query Sequence  ECWRGRPEER. . . . . PTFEFLQS
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Template Sequence  GLLKKDPKQRLGGGSEDAKEIMQ
Template Known Secondary structure  T
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   382.......390.........400....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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