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Job DescriptionP16277
Confidence100.00%DateTue Jul 30 13:14:40 BST 2013
Rank194Aligned Residues249
% Identity25%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   233......240.........250.........260.........270.........280.........290..
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Query Sequence  QSLKLVRKLGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKTLQHERLVR
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Template Sequence  RDITLLECVGKGRYGEVWRGSW. QGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILG
Template Known Secondary structure  TTTT.TT
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   206...210.........220....... ..230.........240.........250.........260....
 
   293...... 300.........310.........320.........330.........340.......
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Query Sequence  LYAVVTR. . . . . EPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQVAEGMAYIER
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Template Sequence  FIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLT. . . TLDTVSCLRIVLSIASGLAHLHI
Template Known Secondary structure  TT

TT
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   265....270.........280.........290........ .300.........310.........320.
 
   348.350 .........360.........370......... 380.........390.....
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Query Sequence  MNS. . . . . . . . IHRDLRAANILVSETLCCKIADFGLARII. . . . DSEYTAQEGAKFPIKW
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Template Sequence  EIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRY
Template Known Secondary structure 
B
STT
B

S

SGGG
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TT
TTTT








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   322.......330.........340.........350.........360.........370.........380.
 
   396...400..... ....410.........420.........430.....
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Query Sequence  TAPEAIHFGV. . . . . . FTIKADVWSFGVLLMEIVTYGRVPYPGMSN. . . . . . . . . . . . . .
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Template Sequence  MAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPNDPS
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TT


TT
T.TB
BTTB





TTTTTS
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   382.......390.........400.........410...... ...420.........430.........440
 
   436...440.........450... ......460.........470.........480.......
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Query Sequence  . PEVIRSLEHGYRMPCPET. . . . . . CPPELYNDIITECWRGRPEERPTFEFLQSVLEDF
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Template Sequence  FEDMRKVVCVDQQRPNIPNRWFSDPTLTSL. AKLMKECWYQNPSARLTALRIKKTLTKI
Template Known Secondary structure  TTS






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   441........450.........460.........470 .........480.........490........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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