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Job DescriptionP16277
Confidence100.00%DateTue Jul 30 13:14:40 BST 2013
Rank178Aligned Residues267
% Identity35%Templatec2yhvA_
PDB info PDB header:transferaseChain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of l1196m mutant anaplastic lymphoma kinase
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   226...230.........240.........250.........260...... ...270.........280...
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Query Sequence  DEWEIPRQSLKLVRKLGSGQFGEVWMGYYKNNMKVAIKTLK. . EGTMSPEAFLGEANVMK
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Template Sequence  DLKEVPRKNITL. . . IRGLAFGEVYEGQV. . PLQVAVKTLPEVCSEQDELDFLMEALIIS
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   1107..1110........ .1120.........1130.. .......1140.........1150.........1160.
 
   284.....290.........300. ........310.........320. ........330.......
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Query Sequence  TLQHERLVRLYAVVTREP. IYIVTEYMARGCLLDFLKTD. . . . . EGSRLSLPRLIDMSAQ
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Template Sequence  KFNHQNIVRCIGVSLQSLPRFILMELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARD
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   1173......1180.........1190.........1200.........1210.........1220.........1230..
 
   338.340.........350.........360.........370.........380.........390.......
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Query Sequence  VAEGMAYIERMNSIHRDLRAANILVSETLCCKIADFGLARIIDSEYTAQEGAKFPIKWTA
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Template Sequence  IACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDF. GMARDIYRGGCAMLPVKWMP
Template Known Secondary structure  TT


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   1233......1240.........1250.........1260.........1270. ........1280.........1290.
 
   398.400.........410.........420.........430.........440.........450.......
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Query Sequence  PEAIHFGVFTIKADVWSFGVLLMEIVTYGRVPYPGMSNPEVIRSLEHGYRMPCPETCPPE
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Template Sequence  PEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGP
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   1298.1300.........1310.........1320.........1330.........1340.........1350.......
 
   458.460.........470.........480.........490.........
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Query Sequence  LYNDIITECWRGRPEERPTFEFLQSVLEDFYTATEGQYELQP
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Template Sequence  V. YRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALP
Template Known Secondary structure  .T
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   1358 .1360.........1370.........1380.........1390........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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