Job Description P16277 Confidence 100.00% Date Tue Jul 30 13:14:40 BST 2013 Rank 77 Aligned Residues 255 % Identity 35% Template c2w1iB_ PDB info PDB header:transferase Chain: B: PDB Molecule:jak2; PDBTitle: structure determination of aurora kinase in complex with2 inhibitor Resolution 2.60 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		229	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.						.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.		.	.	.	.	.	.	.	280	.	.
Predicted Secondary structure																														.	.	.	.	.																	.
Query SS confidence																														.	.	.	.	.																	.
Query Sequence		E	I	P	R	Q	S	L	K	L	V	R	K	L	G	S	G	Q	F	G	E	V	W	M	G	Y	Y	K	N	.	.	.	.	.	N	M	K	V	A	I	K	T	L	K	E	G	T	M	S	P	.	E	A	F	L	G	E	A	N	V	M
Query Conservation																														.	.	.	.	.																	.
Alig confidence																														.	.	.	.	.																	.
Template Conservation
Template Sequence		Q	F	E	E	R	H	L	K	F	L	Q	Q	L	G	K	G	N	F	G	S	V	E	M	C	R	Y	D	P	L	Q	D	N	T	G	E	V	V	A	V	K	K	L	Q	H	S	T	E	E	H	L	R	D	F	E	R	E	I	E	I	L
Template Known Secondary structure					G	G	G											T	T										S	S		S	S											S	S			S
Template Predicted Secondary structure
Template SS confidence
		843	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.
		283	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	T	L	Q	H	E	R	L	V	R	L	Y	A	V	V	T	R	E	P	I	Y	I	V	T	E	Y	M	A	R	G	C	L	L	D	F	L	K	T	D	E	G	S	R	L	S	L	P	R	L	I	D	M	S	A	Q	V	A	E	G	M
Query Conservation
Alig confidence																					.																				.
Template Conservation																					.																				.
Template Sequence		K	S	L	Q	H	D	N	I	V	K	Y	K	G	V	C	Y	S	N	L	.	K	L	I	M	E	Y	L	P	Y	G	S	L	R	D	Y	L	Q	K	H	.	K	E	R	I	D	H	I	K	L	L	Q	Y	T	S	Q	I	C	K	G	M
Template Known Secondary structure							T	T	B												.								T	T		B								T	.	T	T	T	S
Template Predicted Secondary structure																					.																				.
Template SS confidence
		903	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.		.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940		.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960
		343	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390		.	.	.	.	.	.	.	.	.	400	.
Predicted Secondary structure																																																		.
Query SS confidence																																																		.
Query Sequence		A	Y	I	E	R	M	N	S	I	H	R	D	L	R	A	A	N	I	L	V	S	E	T	L	C	C	K	I	A	D	F	G	L	A	R	I	I	D	S	E	Y	T	A	Q	E	G	A	K	.	F	P	I	K	W	T	A	P	E	A	I
Query Conservation																																																		.
Alig confidence																																																		.
Template Conservation
Template Sequence		E	Y	L	G	T	K	R	Y	I	H	R	D	L	A	T	R	N	I	L	V	E	N	E	N	R	V	K	I	G	D	F	G	L	T	K	V	L	P	Q	D	K	E	K	V	K	E	P	G	E	S	P	I	F	W	Y	A	P	E	S	L
Template Known Secondary structure							T	T				S				G	G	G						T	T								T	T						T	T					S	S			S			G	G	G
Template Predicted Secondary structure
Template SS confidence
		965	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.
		402	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.																	.	.	.	.	.	.	.	440	.	.	.	.	.
Predicted Secondary structure																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		H	F	G	V	F	T	I	K	A	D	V	W	S	F	G	V	L	L	M	E	I	V	T	Y	G	R	V	P	Y	P	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	M	S	N	P	E	V	I	R	S	L	E	H	G
Query Conservation																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																									.								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																									.
Template Sequence		T	E	S	K	F	S	V	A	S	D	V	W	S	F	G	V	V	L	Y	E	L	F	T	.	Y	I	E	K	S	K	S	P	P	A	E	F	M	R	M	I	G	N	D	K	Q	G	Q	M	I	V	F	H	L	I	E	L	L	K	N	N
Template Known Secondary structure																									.	T	T		G	G	G	S											T	T			S													T	T
Template Predicted Secondary structure																									.
Template SS confidence
		1027	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.		1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.
		446	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	R	M	P	C	P	E	T	C	P	P	E	L	Y	N	D	I	I	T	E	C	W	R	G	R	P	E	E	R	P	T	F	E	F	L	Q	S	V	L	E	D	F
Query Conservation
Alig confidence															.
Template Conservation															.
Template Sequence		G	R	L	P	R	P	D	G	C	P	D	E	I	.	Y	M	I	M	T	E	C	W	N	N	N	V	N	Q	R	P	S	F	R	D	L	A	L	R	V	D	Q	I
Template Known Secondary structure								T	T						.								S		S	S	G	G	G	S
Template Predicted Secondary structure															.
Template SS confidence
		1086	.	.	.	1090	.	.	.	.	.	.	.	.		.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D