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Job DescriptionP16277
Confidence100.00%DateTue Jul 30 13:14:40 BST 2013
Rank146Aligned Residues239
% Identity23%Templatec2r7bA_
PDB info PDB header:signaling protein, transferaseChain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   231........240.........250.... .....260...... ...270.........280.....
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Query Sequence  PRQSLKLVRKLGSGQFGEVWMGYY. KNNMKVAIKTLK. . . . EGTMSPEAFLGEANVMKTL
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Template Sequence  RPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRL
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   78.80.........90.........100.........110.........120.........130.......
 
   286...290.........300. ........310.........320.........330.........340....
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Query Sequence  QHERLVRLYAVVTREP. IYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQVAEGMAY
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Template Sequence  DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIG. . SFDETCTRFYTAEIVSALEY
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   138.140.........150.........160.........170..... ....180.........190.....
 
   345....350.........360.........370.........380.........390.........400....
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Query Sequence  IERMNSIHRDLRAANILVSETLCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFG
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Template Sequence  LHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL. . . . . . . . . FVGTAQYVSPELLTEK
Template Known Secondary structure  TT




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   196...200.........210.........220.........230 .........240......
 
   405....410.........420.........430.........440.........450.........460....
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Query Sequence  VFTIKADVWSFGVLLMEIVTYGRVPYPGMSNPEVIRSLEHGYRMPCPETCPPELYNDIIT
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Template Sequence  SACKSSDLWALGCIIYQLVA. GLPPFRAGNEYLIFQKIIKLE. YDFPEKFFPKA. RDLVE
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   258.260.........270....... ..280.........290........ .300......... 310....
 
   465....470.........480...
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Query Sequence  ECWRGRPEERPTFEFLQSV
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Template Sequence  KLLVLDATKRLGCEEMEGY
Template Known Secondary structure  TTS
SSTTSSTTSGGGTT
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   315....320.........330...
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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