Job Description P16277 Confidence 100.00% Date Tue Jul 30 13:14:40 BST 2013 Rank 284 Aligned Residues 244 % Identity 20% Template c2pvmA_ PDB info PDB header:transferase Chain: A: PDB Molecule:casein kinase ii subunit alpha; PDBTitle: structure-based design of pyrazolo[1,5-a][1,3,5]triazine2 derivatives as potent inhibitors of protein kinase ck2 Resolution 2.00 Å

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		230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.		.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.
Predicted Secondary structure																											.
Query SS confidence																											.
Query Sequence		I	P	R	Q	S	L	K	L	V	R	K	L	G	S	G	Q	F	G	E	V	W	M	G	Y	Y	.	K	N	N	M	K	V	A	I	K	T	L	K	E	G	T	M	S	P	E	A	F	L	G	E	A	N	V	M	K	T	L	Q	H	E
Query Conservation																											.
Alig confidence																											.													.	.
Template Conservation																																								.	.
Template Sequence		G	E	Q	D	D	Y	E	V	V	R	K	V	G	R	G	K	Y	S	E	V	F	E	G	I	N	V	N	N	N	E	K	C	I	I	K	I	L	K	.	.	P	V	K	K	K	K	I	K	R	E	I	K	I	L	Q	N	L	G	G	P
Template Known Secondary structure				G	G	G											S	S									T	T	T											.	.	S																			T
Template Predicted Secondary structure																																								.	.
Template SS confidence
		34	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.			.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.
		289	290	.	.	.	.	.	.	.	.	.	300	.				.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.
Predicted Secondary structure															.	.	.
Query SS confidence															.	.	.
Query Sequence		R	L	V	R	L	Y	A	V	V	T	R	E	P	.	.	.	I	Y	I	V	T	E	Y	M	A	R	G	C	L	L	D	F	L	K	T	D	E	G	S	R	L	S	L	P	R	L	I	D	M	S	A	Q	V	A	E	G	M	A	Y	I
Query Conservation															.	.	.
Alig confidence															.	.	.																			.	.	.	.	.
Template Conservation																																				.	.	.	.	.
Template Sequence		N	I	V	K	L	L	D	I	V	R	D	Q	H	S	K	T	P	S	L	I	F	E	Y	V	N	N	T	D	F	K	V	L	Y	P	.	.	.	.	.	T	L	T	D	Y	D	I	R	Y	Y	I	Y	E	L	L	K	A	L	D	Y	C
Template Known Secondary structure		T	B										T	T	T																			G	G	.	.	.	.	.	G
Template Predicted Secondary structure																																				.	.	.	.	.
Template SS confidence
		93	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.						.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.
		346	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.		.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.
Predicted Secondary structure																					.																																								.
Query SS confidence																					.																																								.
Query Sequence		E	R	M	N	S	I	H	R	D	L	R	A	A	N	I	L	V	S	E	.	T	L	C	C	K	I	A	D	F	G	L	A	R	I	I	D	S	E	Y	T	A	Q	E	G	A	K	F	P	I	K	W	T	A	P	E	A	I	H	F	.
Query Conservation																					.																																								.
Alig confidence																					.																													.											.
Template Conservation																																																		.
Template Sequence		H	S	Q	G	I	M	H	R	D	V	K	P	H	N	V	M	I	D	H	E	L	R	K	L	R	L	I	D	W	G	L	A	E	F	Y	H	P	G	K	E	Y	N	V	R	V	A	S	R	.	Y	F	K	G	P	E	L	L	V	D	L
Template Known Secondary structure				T	T							S	G	G	G					T	T	T	T								T	T						T	T					S			S		G	.	G	G							T	T
Template Predicted Secondary structure																																																		.
Template SS confidence
		148	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.		.	.	.	.	200	.	.	.	.	.	.
		404	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.
Predicted Secondary structure																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		G	V	F	T	I	K	A	D	V	W	S	F	G	V	L	L	M	E	I	V	T	Y	G	R	V	P	Y	P	G	M	S	N	P	E	V	I	R	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		Q	D	Y	D	Y	S	L	D	M	W	S	L	G	C	M	F	A	G	M	I	F	R	K	E	P	F	F	Y	G	H	D	N	H	D	Q	L	V	K	I	A	K	V	L	G	T	D	G	L	N	A	Y	L	N	K	Y	R	I	E	L	D
Template Known Secondary structure			S			T																	T		S	S	S	S			S	S																								T	T
Template Predicted Secondary structure
Template SS confidence
		207	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.
																442	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	L	E	H	G	Y	R	M	P	C	P	E	T	C	P	P	E	L	Y	N	D	I	I	T	E	C	W	R	G	R	P	E	E	R	P	T	F	E	F	L	Q	S
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.																		.
Template Conservation																																	.
Template Sequence		P	Q	L	E	A	L	V	G	R	H	S	R	K	P	W	L	K	F	M	N	A	D	N	Q	H	L	V	S	P	E	A	.	I	D	F	L	D	K	L	L	R	Y	D	H	Q	E	R	L	T	A	L	E	A	M	T
Template Known Secondary structure																G	G	G	G			T	T	T	G	G	G						.						T	T			S	S	T	T	T	S
Template Predicted Secondary structure																																	.
Template SS confidence
		267	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.		.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D