Job Description P16277 Confidence 100.00% Date Tue Jul 30 13:14:40 BST 2013 Rank 287 Aligned Residues 267 % Identity 23% Template c2ojiA_ PDB info PDB header:transferase Chain: A: PDB Molecule:mitogen-activated protein kinase 1; PDBTitle: crystal structure of erk2 in complex with n-benzyl-4-(4-(3-2 chlorophenyl)-1h-pyrazol-3-yl)-1h-pyrrole-2-carboxamide Resolution 2.60 Å

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		226	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.		.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.			.	.	.	.	.	.	.	.	280	.	.
Predicted Secondary structure																																.																	.	.
Query SS confidence																																.																	.	.
Query Sequence		D	E	W	E	I	P	R	Q	S	L	K	L	V	R	K	L	G	S	G	Q	F	G	E	V	W	M	G	Y	Y	K	.	N	N	M	K	V	A	I	K	T	L	K	E	G	T	M	S	.	.	P	E	A	F	L	G	E	A	N	V	M
Query Conservation																																.																	.	.
Alig confidence								.																								.																	.	.
Template Conservation								.
Template Sequence		Q	V	F	D	V	G	.	P	R	Y	T	N	L	S	Y	I	G	E	G	A	Y	G	M	V	C	S	A	Y	D	N	V	N	K	V	R	V	A	I	K	K	I	S	P	F	E	H	Q	T	Y	C	Q	R	T	L	R	E	I	K	I	L
Template Known Secondary structure		S						.	S	S											T	T									T	T	T	T											T	T	S
Template Predicted Secondary structure								.
Template SS confidence
		15	.	.	.	.	20		.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.
		283	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.							.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.
Predicted Secondary structure																					.	.	.	.	.	.
Query SS confidence																					.	.	.	.	.	.
Query Sequence		K	T	L	Q	H	E	R	L	V	R	L	Y	A	V	V	T	R	E	P	.	.	.	.	.	.	I	Y	I	V	T	E	Y	M	A	R	G	C	L	L	D	F	L	K	T	D	E	G	S	R	L	S	L	P	R	L	I	D	M	S	A
Query Conservation																					.	.	.	.	.	.
Alig confidence																					.	.	.	.	.	.																					.	.	.	.
Template Conservation																																															.	.	.	.
Template Sequence		L	R	F	R	H	E	N	I	I	G	I	N	D	I	I	R	A	P	T	I	E	Q	M	K	D	V	Y	I	V	Q	D	L	M	E	T	D	L	Y	K	L	L	K	T	Q	H	.	.	.	.	L	S	N	D	H	I	C	Y	F	L	Y
Template Known Secondary structure							T	T	B										S	S	T	T	T												S												.	.	.	.
Template Predicted Secondary structure																																															.	.	.	.
Template SS confidence
		74	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.					.	120	.	.	.	.	.	.	.	.	.
		337	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390					.	.
Predicted Secondary structure																																																								.	.	.	.
Query SS confidence																																																								.	.	.	.
Query Sequence		Q	V	A	E	G	M	A	Y	I	E	R	M	N	S	I	H	R	D	L	R	A	A	N	I	L	V	S	E	T	L	C	C	K	I	A	D	F	G	L	A	R	I	I	D	S	E	Y	T	A	Q	E	G	A	K	.	.	.	.	F	P
Query Conservation																																																								.	.	.	.
Alig confidence																																																								.	.	.	.
Template Conservation
Template Sequence		Q	I	L	R	G	L	K	Y	I	H	S	A	N	V	L	H	R	D	L	K	P	S	N	L	L	L	N	T	T	C	D	L	K	I	C	D	F	G	L	A	R	V	A	D	P	D	H	D	H	T	G	F	L	T	E	Y	V	A	T	R
Template Known Secondary structure													T	T								G	G	G					T	T									S	S						G	G	G		B			T	T					S		G
Template Predicted Secondary structure
Template SS confidence
		130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.
		393	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.
Predicted Secondary structure																																																													.
Query SS confidence																																																													.
Query Sequence		I	K	W	T	A	P	E	A	I	H	F	G	V	F	T	I	K	A	D	V	W	S	F	G	V	L	L	M	E	I	V	T	Y	G	R	V	P	Y	P	G	M	S	N	P	E	V	I	R	S	L	E	H	G	Y	R	M	P	C	P	.
Query Conservation																																																													.
Alig confidence																																		.																											.
Template Conservation																																		.
Template Sequence		W	Y	R	A	P	E	I	M	L	N	S	K	G	Y	T	K	S	I	D	I	W	S	V	G	C	I	L	A	E	M	L	S	.	N	R	P	I	F	P	G	K	H	Y	L	D	Q	L	N	H	I	L	G	I	L	G	S	P	S	Q	E
Template Known Secondary structure		G	G								T	B		S		S	T																	.	S	S		S	S			S	S	T	T												S
Template Predicted Secondary structure																																		.
Template SS confidence
		190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.		.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.
																															452	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	T	C	P	P	E	L	Y	N	D	I	I	T	E	C	W	R	G	R	P	E	E	R	P	T	F	E	F	L	Q	S
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.								.
Template Conservation																																						.
Template Sequence		D	L	N	C	I	I	N	L	K	A	R	N	Y	L	L	S	L	P	H	K	N	K	V	P	W	N	R	L	F	P	N	A	D	S	K	A	.	L	D	L	L	D	K	M	L	T	F	N	P	H	K	R	I	E	V	E	Q	A	L	A
Template Known Secondary structure					S												T	S													T	T	S					.								T		S	S	T	T	T	S								T
Template Predicted Secondary structure																																						.
Template SS confidence
		249	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.		.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.
				483	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.
Query SS confidence		.	.
Query Sequence		.	.	V	L	E	D	F	Y	T	A	T	E	G	Q	Y	E	L	Q	P
Query Conservation		.	.
Alig confidence		.	.
Template Conservation
Template Sequence		H	P	Y	L	E	Q	Y	Y	D	P	S	D	E	P	I	A	E	A	P
Template Known Secondary structure		S	G	G	G	T	T	T			G	G	G	S				S	S
Template Predicted Secondary structure
Template SS confidence
		308	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D