|   |   |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
I | P | R | Q | S | L | K | L | V | R | K | L | G | S | G | Q | F | G | E | V | W | M | G | Y | Y | K | N | N | M | K | V | A | I | K | T | L | K | E | G | T | M | S | P | E | A | F | L | G | E | A | N | V | M | K | T | L | Q | H | E | R |
| Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |
|   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   | . |   |
|   |   |
|
|
|
|   |
|   | . |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |
|
|
|
| Template Sequence |   |
I | D | Y | K | E | I | E | V | E | E | V | V | G | R | G | A | F | G | V | V | C | K | A | K | W | . |
R | A | K | D | V | A | I | K | Q | I | E | . |
S | E | S | E | R | K | A | F | I | V | E | L | R | Q | L | S | R | V | N | H | P | N |
| Template Known Secondary structure |   |
|
| G | G | G |  |  |  |  |  |  |  |  |
|
| S | S | S |  |  |  |  |  |  |  | . | T | T |  |  |  |  |  |  |  |
| S | . | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T |
| Template Predicted Secondary structure |   |
|
|  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . |
|
|  |  |  |  |  |  |  |  |
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
31 | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
. | . | . | . | 60 | . | . | . | . | . | . | |
. | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . |
|   |
|   |   |
290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | V | R | L | Y | A | V | V | T | R | E | P | I | Y | I | V | T | E | Y | M | A | R | G | C | L | L | D | F | L | K | T | D | E | G | S | R | L | S | L | P | R | L | I | D | M | S | A | Q | V | A | E | G | M | A | Y | I | E | R | M | N |
| Query Conservation |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
I | V | K | L | Y | G | A | C | L | N | P | V | C | L | V | M | E | Y | A | E | G | G | S | L | Y | N | V | L | H | G | A | E | P | L | P | Y | Y | T | A | A | H | A | M | S | W | C | L | Q | C | S | Q | G | V | A | Y | L | H | S | M | Q |
| Template Known Secondary structure |   |
B |
|
|  |  |  | B |
| T | T | T | T |  |  |  |  |  |
|
| T | T |
| B |  |  |  |  |  |  |
| S | S | S |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
89 | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . |
|   |
|   |   |
350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
S | I | H | R | D | L | R | A | A | N | I | L | V | S | E | T | L | C | C | K | I | A | D | F | G | L | A | R | I | I | D | S | E | Y | T | A | Q | E | G | A | K | F | P | I | K | W | T | A | P | E | A | I | H | F | G | V | F | T | I | K |
| Query Conservation |   |
  |
|
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |
|   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
P | K | A | L | I | H | R | D | L | K | P | P | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | L | L | V | A | G | G | T | V | L | K | I | C | D | F | G | T | G | S | A | A | W | M | A | P | E | V | F | E | G | S | N | Y | S | E | K |
| Template Known Secondary structure |   |
S | S |
|
|
|
|
|
|
| S | G | G | G | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  | T | T | T | T |  |  |  |  |
|
|
|
|
|
|
| T | T | S | S |
|  |  |  |  | T |
|
|
|
|
| T |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
149 | 150 | . | . | . | . | . | . | . | . | . | 160 | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . |
|   |
|   |   |
410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | |
|
. | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | D | V | W | S | F | G | V | L | L | M | E | I | V | T | Y | G | R | V | P | Y | . |
. |
P | G | M | S | N | P | E | V | I | R | S | L | E | H | G | Y | R | M | P | C | P | E | T | C | P | P | E | L | Y | N | D | I | I | T | E | C | W |
| Query Conservation |   |
|
|
|
|
|   |
|
|
|
|   |
|
|   |
|   |
|   |   |
|   | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|   |
|
|
|   |   |
|   |
|
|   |   | . |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . |   |   |
|
|   |   |
|
|
| Template Sequence |   |
C | D | V | F | S | W | G | I | I | L | W | E | V | I | T | . |
R | R | K | P | F | D | E | I | G | G | P | A | F | R | I | M | W | A | V | H | N | G | T | R | P | P | L | I | K | N | L | P | K | P | I | . |
E | S | L | M | T | R | C | W |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | T |
|
| T | T | T | T | T |
| S | S |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
| B | T | T |
|
|  |  |  | . |  |  |  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  | . |  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | |
. | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | |
260 | . | . | . | . | . | . | . |
|   |
|   |   |
468 | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | G | R | P | E | E | R | P | T | F | E | F | L | Q | S | V | L | E | D | F | Y | T | A | T | E | G | Q | Y | E | L | Q | P |
| Query Conservation |   |
  |   |
|
|   |   |
|
|
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|
|   |   |
|
|
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
S | K | D | P | S | Q | R | P | S | M | E | E | I | V | K | I | M | T | H | L | M | R | Y | F | P | G | A | D | E | P | L | Q |
| Template Known Secondary structure |   |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  | G | G | G |
|
|
| T | T | S |
|
|
|
| Template Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
268 | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . |
|   |