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Job DescriptionP16277
Confidence100.00%DateTue Jul 30 13:14:40 BST 2013
Rank280Aligned Residues232
% Identity23%Templatec2dylA_
PDB info PDB header:transferaseChain: A: PDB Molecule:dual specificity mitogen-activated protein PDBTitle: crystal structure of human mitogen-activated protein kinase2 kinase 7 activated mutant (s287d, t291d)
Resolution2.45 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   230....... ..240.........250.... .....260.........270.... .....280....
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Query Sequence  IPRQSLKL. VRKLGSGQFGEVWMGYY. KNNMKVAIKTLKEGTMSPEA. . . FLGEANVMKT
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Template Sequence  IGGQRYQAEINDLENLGEMQVWKMRFRKTGHVIAVKQMRRSGNKEENKRILMDLDVVLKS
Template Known Secondary structure  SSS

GGG

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   124.....130.........140.........150.........160.........170.........180...
 
   285....290.........300. ........310.........320.........330.........340...
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Query Sequence  LQHERLVRLYAVVTREP. IYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQVAEGMA
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Template Sequence  HDCPYIVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQ. GPIPERILGKMTVAIVKALYY
Template Known Secondary structure  TT
TTB


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   190.........200.........210.........220....... ..230.........240........
 
   344.....350.........360.........370.........380.........390.........400...
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Query Sequence  YIERMNSIHRDLRAANILVSETLCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHF
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Template Sequence  LKEKHGVIHRDVKPSNILLDERGQIKLCDFGIS. . . . . . . . . . . . . . . . . . CAAYMAPER
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   249250.........260.........270.........280. ........290
 
   404.....410.........420.........430...... ...440...... ...450.........460
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Query Sequence  GVFTIKADVWSFGVLLMEIVTYGRVPYPGMSNP. EVIRSLEHGY. . RMPCPETCPPELYN
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Template Sequence  IDYDIRADVWSLGISLVELAT. GQFPYKNCKTDFEVLTKVLQEEPPLLPGHMGFSGDF. Q
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   305....310.........320..... ....330.........340.........350.........360. .
 
   461........470.........480..
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Query Sequence  DIITECWRGRPEERPTFEFLQS
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Template Sequence  SFVKDCLTKDHRKRPKYNKLLE
Template Known Secondary structure  T
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TTTS

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   371........380.........390..
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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