|   |   |
233 | . | . | . | . | . | . | 240 | |
. | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | |
. | . | . | . | 260 | . | . | . | . | . | |
. | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | |
. | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |
| . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
| Query Sequence |   |
Q | S | L | K | L | V | R | K | . |
L | G | S | G | Q | F | G | E | V | W | M | G | Y | Y | K | . |
N | N | M | K | V | A | I | K | T | L | . |
K | E | G | T | M | S | P | E | A | F | L | G | E | A | N | V | M | K | T | L | . |
Q | H | E |
| Query Conservation |   |
  |   |   |   |   |   |   |   | . |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   | . |   |   |   |   |
|
|
|
|   |
| . |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |
| . |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
| Template Conservation |   |
  |   |
|   |
|   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |
|
|
| Template Sequence |   |
D | V | Y | Q | L | Q | E | D | V | L | G | E | G | A | H | A | R | V | Q | T | C | I | N | L | I | T | S | Q | E | Y | A | V | K | I | I | E | K | Q | P | G | H | I | R | S | R | V | F | R | E | V | E | M | L | Y | Q | C | Q | G | H | R |
| Template Known Secondary structure |   |
G | S |
|  |  |  |  |  | S |
|
|
|
| S | S |  |  |  |  |  |  |  |
| S | S | S |
|
|  |  |  |  |  |  |  |  |
|
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
| T |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 |
|   |
|   |   |
289 | 290 | . | . | . | . | . | . | . | . | . | 300 | . | |
. | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|
| . |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
R | L | V | R | L | Y | A | V | V | T | R | E | P | . |
I | Y | I | V | T | E | Y | M | A | R | G | C | L | L | D | F | L | K | T | D | E | G | S | R | L | S | L | P | R | L | I | D | M | S | A | Q | V | A | E | G | M | A | Y | I | E | R |
| Query Conservation |   |
|
|
|   |
|   |
|   |   |   |   |   |   | . |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |
|
|
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
N | V | L | E | L | I | E | F | F | E | E | E | D | R | F | Y | L | V | F | E | K | M | R | G | G | S | I | L | S | H | I | H | K | R | R | . |
. |
H | F | N | E | L | E | A | S | V | V | V | Q | D | V | A | S | A | L | D | F | L | H | N |
| Template Known Secondary structure |   |
T | B |
|
|  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |
|
| T | T |
| B |  |  |  |  |  |  |  |  | S | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
|  |  |  |
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
141 | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | |
|
. | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . |
|   |
|   |   |
348 | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
M | N | S | I | H | R | D | L | R | A | A | N | I | L | V | S | E | T | L | C | C | K | I | A | D | F | G | L | A | R | I | I | D | S | E | Y | T | A | Q | E | G | A | K | F | P | I | K | W | T | A | P | E | A | I | H | F | G | V | F | T |
| Query Conservation |   |
  |   |   |
|
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
K | G | I | A | H | R | D | L | K | P | E | N | I | L | C | E | H | P | N | Q | V | S | P | V | K | I | C | D | F | G | . |
. |
. |
. |
. |
. |
P | C | G | S | A | E | Y | M | A | P | E | V | V | E | A | F | S | E | E | A | S | I | Y | D |
| Template Known Secondary structure |   |
T | T |
|
|
| S |
|
|
| G | G | G |
|  |  |  |  | T | T |  |  |  |  |  |  | B |
|
|
|
| . | . | . | . | . | . |
|
| S | S | G | G | G |
|
|  |  |  |  |  | S | S | S |  |  |  |  | T | T | T |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
199 | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
|   |
|   |   |
408 | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | |
|
|
. |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
| Query Sequence |   |
I | K | A | D | V | W | S | F | G | V | L | L | M | E | I | V | T | Y | G | R | V | P | Y | P | G | M | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | P | E | V | I | R | S | L | E | H | G | Y | R | M | P | C | P | E | . |
. |
. |
T |
| Query Conservation |   |
  |
|
|
|
|
|
|   |
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |
|   | . | . | . |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
| Template Conservation |   |
  |   |   |
|
|
|
|   |
|   |   |
|   |
|
|   |   | . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
K | R | C | D | L | W | S | L | G | V | I | L | Y | I | L | L | S | . |
G | Y | P | P | F | V | G | R | C | G | S | D | C | G | W | A | C | P | A | C | Q | N | M | L | F | E | S | I | Q | E | G | K | Y | E | F | P | D | K | D | W | A | H |
| Template Known Secondary structure |   |
T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
|
|
|
| S | S |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|  |  |  |  | T | T |
| Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
274 | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | |
. | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . |
|   |
|   |   |
454 | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . |
| Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
C | P | P | E | L | Y | N | D | I | I | T | E | C | W | R | G | R | P | E | E | R | P | T | F | E | F | L | Q | S |
| Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   | . |   |   |
|
|   |   |   |
|   |   |
|
|   |   |
|
|
|
|   |
|
|
|   |
| Template Sequence |   |
I | S | C | A | A | . |
K | D | L | I | S | K | L | L | V | R | D | A | K | Q | R | L | S | A | A | Q | V | L | Q |
| Template Known Secondary structure |   |
S |
|  |  |  | . |  |  |  |  |  |  |  | S |
| S |
| T | T | T | S |
|
|  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|  |  |  | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
337 | . | . | 340 | . | |
. | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . |
|   |