Job Description P16277 Confidence 100.00% Date Tue Jul 30 13:14:40 BST 2013 Rank 1 Aligned Residues 442 % Identity 62% Template c1y57A_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor Resolution 1.91 Å Model Dimensions (Å) X:62.557 Y:103.346 Z:43.872

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		54	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.		.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.
Predicted Secondary structure																																	.
Query SS confidence																																	.
Query Sequence		E	R	F	V	V	A	L	F	D	Y	A	A	V	N	D	R	D	L	Q	V	L	K	G	E	K	L	Q	V	L	R	S	.	T	G	D	W	W	L	A	R	S	L	V	T	G	R	E	G	Y	V	P	S	N	F	V	A	P	V	E	T
Query Conservation																																	.
Alig confidence																																	.
Template Conservation
Template Sequence		V	T	T	F	V	A	L	Y	D	Y	E	S	R	T	E	T	D	L	S	F	K	K	G	E	R	L	Q	I	V	N	N	T	E	G	D	W	W	L	A	H	S	L	S	T	G	Q	T	G	Y	I	P	S	N	Y	V	A	P	S	D	S
Template Known Secondary structure		T	T					S	S		B				S	S	S	B			B		T	T						S			S	S	S	S							T	T	T								G	G	G				T	T	S
Template Predicted Secondary structure
Template SS confidence
		83	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.
		113	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.		.	.	.	.	.	.	170	.
Predicted Secondary structure																																																					.
Query SS confidence																																																					.
Query Sequence		L	E	V	E	K	W	F	F	R	T	I	S	R	K	D	A	E	R	Q	L	L	A	P	M	N	K	A	G	S	F	L	I	R	E	S	E	S	N	K	G	A	F	S	L	S	V	K	D	I	T	T	.	Q	G	E	V	V	K	H	Y
Query Conservation																																																					.
Alig confidence																																																					.
Template Conservation
Template Sequence		I	Q	A	E	E	W	Y	F	G	K	I	T	R	R	E	S	E	R	L	L	L	N	A	E	N	P	R	G	T	F	L	V	R	E	S	E	T	T	K	G	A	Y	C	L	S	V	S	D	F	D	N	A	K	G	L	N	V	K	H	Y
Template Known Secondary structure		G	G	G	S	T	T				S											T		T	T			T	T								S	S	S	T	T											T	T	T
Template Predicted Secondary structure
Template SS confidence
		143	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.
		172	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.		.	.	.	.	.	230
Predicted Secondary structure																																																							.
Query SS confidence																																																							.
Query Sequence		K	I	R	S	L	D	N	G	G	Y	Y	I	S	P	R	I	T	F	P	T	L	Q	A	L	V	Q	H	Y	S	K	K	G	D	G	L	C	Q	K	L	T	L	P	C	V	N	L	A	P	K	N	L	W	A	.	Q	D	E	W	E	I
Query Conservation																																																							.
Alig confidence																																																							.
Template Conservation
Template Sequence		K	I	R	K	L	D	S	G	G	F	Y	I	T	S	R	T	Q	F	N	S	L	Q	Q	L	V	A	Y	Y	S	K	H	A	D	G	L	C	H	R	L	T	T	V	C	P	T	S	K	P	Q	T	Q	G	L	A	K	D	A	W	E	I
Template Known Secondary structure							S	S	S				S	S	T	T	S			S	S													T	T	S	S	S					B									S	S					T	T	B
Template Predicted Secondary structure
Template SS confidence
		203	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.
		231	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290
Predicted Secondary structure
Query SS confidence
Query Sequence		P	R	Q	S	L	K	L	V	R	K	L	G	S	G	Q	F	G	E	V	W	M	G	Y	Y	K	N	N	M	K	V	A	I	K	T	L	K	E	G	T	M	S	P	E	A	F	L	G	E	A	N	V	M	K	T	L	Q	H	E	R	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	R	E	S	L	R	L	E	V	K	L	G	Q	G	C	F	G	E	V	W	M	G	T	W	N	G	T	T	R	V	A	I	K	T	L	K	P	G	T	M	S	P	E	A	F	L	Q	E	A	Q	V	M	K	K	L	R	H	E	K	L
Template Known Secondary structure			G	G	G											T	T									T	T	T										T	T	S	S																		T	T	B
Template Predicted Secondary structure
Template SS confidence
		263	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.
		291	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Predicted Secondary structure
Query SS confidence
Query Sequence		V	R	L	Y	A	V	V	T	R	E	P	I	Y	I	V	T	E	Y	M	A	R	G	C	L	L	D	F	L	K	T	D	E	G	S	R	L	S	L	P	R	L	I	D	M	S	A	Q	V	A	E	G	M	A	Y	I	E	R	M	N	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	Q	L	Y	A	V	V	S	E	E	P	I	Y	I	V	T	E	Y	M	S	K	G	S	L	L	D	F	L	K	G	E	T	G	K	Y	L	R	L	P	Q	L	V	D	M	A	A	Q	I	A	S	G	M	A	Y	V	E	R	M	N	Y
Template Known Secondary structure										S	S	S									T	T									S																												T	T
Template Predicted Secondary structure
Template SS confidence
		323	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.
		351	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.		.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																													.
Query SS confidence																													.
Query Sequence		I	H	R	D	L	R	A	A	N	I	L	V	S	E	T	L	C	C	K	I	A	D	F	G	L	A	R	.	I	I	D	S	E	Y	T	A	Q	E	G	A	K	F	P	I	K	W	T	A	P	E	A	I	H	F	G	V	F	T	I	K
Query Conservation																													.
Alig confidence																													.
Template Conservation
Template Sequence		V	H	R	D	L	R	A	A	N	I	L	V	G	E	N	L	V	C	K	V	A	D	F	G	L	A	R	L	I	E	D	N	E	Y	T	A	R	Q	G	A	K	F	P	I	K	W	T	A	P	E	A	A	L	Y	G	R	F	T	I	K
Template Known Secondary structure				S			S	G	G	G					G	G	G								T	T						S	S						T	T	T	T		S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		383	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.
		410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	D	V	W	S	F	G	V	L	L	M	E	I	V	T	Y	G	R	V	P	Y	P	G	M	S	N	P	E	V	I	R	S	L	E	H	G	Y	R	M	P	C	P	E	T	C	P	P	E	L	Y	N	D	I	I	T	E	C	W	R	G
Query Conservation
Alig confidence																																																					.
Template Conservation																																																					.
Template Sequence		S	D	V	W	S	F	G	I	L	L	T	E	L	T	T	K	G	R	V	P	Y	P	G	M	V	N	R	E	V	L	D	Q	V	E	R	G	Y	R	M	P	C	P	P	E	C	P	E	S	L	H	D	.	L	M	C	Q	C	W	R	K
Template Known Secondary structure																T	T	S			S	S	T	T												T	T							T	T								.						T		S
Template Predicted Secondary structure																																																					.
Template SS confidence
		443	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.		.	.	.	.	.	.	500	.
		470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	P	E	E	R	P	T	F	E	F	L	Q	S	V	L	E	D	F	Y	T	A	T	E	G	Q	Y	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	P	E	E	R	P	T	F	E	Y	L	Q	A	F	L	E	D	Y	F	T	S	T	E	P	Q	Y	Q
Template Known Secondary structure		S	G	G	G	S												T					T		T	T
Template Predicted Secondary structure
Template SS confidence
		502	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.