|   |   |
387 | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | |
. | . | . | . | . | . | 420 | . | . | . | . | |
|
|
|
. | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . |
| Predicted Secondary structure |   |
 |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | L | K | R | E | E | I | T | L | L | K | E | L | G | N | G | Q | F | G | V | V | Q | L | G | Q | W | K | . |
G | Q | Y | D | V | A | V | K | M | I | K | . |
. |
. |
. |
E | G | A | M | S | E | D | E | F | F | Q | E | A | Q | T | M | M |
| Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . |   |   |   |   |
|
|
|
|   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
| Template Sequence |   |
K | V | T | M | N | D | F | D | Y | L | K | L | L | G | K | G | T | F | G | K | V | I | L | V | R | E | K | A | T | G | R | Y | Y | A | M | K | I | L | R | K | E | V | I | I | A | K | D | E | V | A | H | T | V | T | E | S | R | V | L | Q |
| Template Known Secondary structure |   |
|
|
| G | G | G |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . |
|   |
|   |   |
442 | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . |
| Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | L | S | H | P | K | L | V | K | F | Y | G | V | C | S | K | K | Y | P | I | Y | I | V | T | E | Y | I | T | N | G | C | L | L | N | Y | L | K | S | H | G | K | G | L | E | S | C | Q | L | L | E | M | C | Y | D | V | C | E | G | M | A |
| Query Conservation |   |
  |
|   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
| Template Sequence |   |
N | T | R | H | P | F | L | T | A | L | K | Y | A | F | Q | T | H | D | R | L | C | F | V | M | E | Y | A | N | G | G | E | L | F | F | H | L | S | R | E | R | V | . |
F | T | E | E | R | A | R | F | Y | G | A | E | I | V | S | A | L | E |
| Template Known Secondary structure |   |
S |
|
|
| T | T | B |
|
|  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |
|
| T | T |
| B |  |  |  |  |  |  |  |  | S |
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
206 | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | |
. | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . |
|   |
|   |   |
502 | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
F | L | E | S | H | Q | F | I | H | R | D | L | A | A | R | N | C | L | V | D | S | D | L | S | V | K | V | S | D | F | G | M | T | R | Y | V | L | D | D | Q | Y | V | S | S | V | G | T | K | F | P | V | K | W | S | A | P | E | V | F | H |
| Query Conservation |   |
  |
|
|   |   |   |   |
|
|   |
|
|   |   |   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |
|
|   |   |   |
| Template Sequence |   |
Y | L | H | S | R | D | V | V | Y | R | D | I | K | L | E | N | L | M | L | D | K | D | G | H | I | K | I | T | D | F | G | L | C | K | E | G | I | S | D | G | A | T | M | K | F | . |
. |
C | G | T | P | E | Y | L | A | P | E | V | L | E |
| Template Known Secondary structure |   |
 |  |  |  | T | T |
| B |
|
|
|
|
| G | G | G |  |  |  |
| T | T | S |
|  |  |  |
|
|
| T | T |
| B |
| S |
|
| T | T |
|
| B |
|
| . | . |
| S |
| G | G | G |
|
| G | G | G | G | S |
| Template Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
265 | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | |
|
310 | . | . | . | . | . | . | . | . | . | 320 | . | . |
|   |
|   |   |
562 | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | F | K | Y | S | S | K | S | D | V | W | A | F | G | I | L | M | W | E | V | F | S | L | G | K | Q | P | Y | D | L | Y | D | N | S | E | V | V | V | K | V | S | Q | G | H | R | L | Y | R | P | Q | L | A | S | D | T | I | Y | Q | I | M |
| Query Conservation |   |
  |   |   |   |   |   |   |
|
|
|
|
|   |
|   |   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|
| Template Sequence |   |
D | N | D | Y | G | R | A | V | D | W | W | G | L | G | V | V | M | Y | E | M | M | C | . |
G | R | L | P | F | Y | N | Q | D | H | E | R | L | F | E | L | I | L | M | . |
E | E | I | R | F | P | R | T | L | S | P | E | A | K | S | L | L |
| Template Known Secondary structure |   |
S | S |
| B |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| S | S |
|
| S | S |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
| T | T | S |
|  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
324 | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | |
. | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | |
. | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . |
|   |
|   |   |
622 | . | . | . | . | . | . | . | 630 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 640 |
| Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |
| . | . | . | . | . |
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | S | C | W | H | E | L | P | E | K | R | . |
. |
. |
. |
. |
P | T | F | Q | Q | L | L | S |
| Query Conservation |   |
  |   |
|   |   |   |   |
|   |   |
| . | . | . | . | . |
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |
|
|   |
|
|
|   |
| Template Sequence |   |
A | G | L | L | K | K | D | P | K | Q | R | L | G | G | G | P | S | D | A | K | E | V | M | E |
| Template Known Secondary structure |   |
 |  |  | T |
| S | S | T | T | T | S | T | T |
| S | T | T | T |  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
382 | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . |
|   |