|   |   |
387 | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 420 | . | . | . | . | . | . | . | |
|
. | . | 430 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | L | K | R | E | E | I | T | L | L | K | E | L | G | N | G | Q | F | G | V | V | Q | L | G | Q | W | K | G | . |
. |
. |
. |
. |
Q | Y | D | V | A | V | K | M | I | K | E | G | A | . |
. |
M | S | E | D | E | F | F | Q | E | A | Q | T |
| Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |
|
|
|
|   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
| Template Sequence |   |
V | F | H | K | R | Y | L | K | K | I | R | D | L | G | E | G | H | F | G | K | V | S | L | Y | C | Y | D | P | T | N | D | G | T | G | E | M | V | A | V | K | A | L | K | E | G | C | G | P | Q | L | R | S | G | W | Q | R | E | I | E | I |
| Template Known Secondary structure |   |
B |
|
| G | G | G |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |
| T | T |
|
| S | S |
|  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
887 | . | . | 890 | . | . | . | . | . | . | . | . | . | 900 | . | . | . | . | . | . | . | . | . | 910 | . | . | . | . | . | . | . | . | . | 920 | . | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . | . | . | . | 940 | . | . | . | . | . | . |
|   |
|   |   |
440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
M | M | K | L | S | H | P | K | L | V | K | F | Y | G | V | C | S | K | K | Y | P | I | Y | I | V | T | E | Y | I | T | N | G | C | L | L | N | Y | L | K | S | H | G | K | G | L | E | S | C | Q | L | L | E | M | C | Y | D | V | C | E | G |
| Query Conservation |   |
|   |   |
|   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
| Template Sequence |   |
L | R | T | L | Y | H | E | H | I | V | K | Y | K | G | C | C | E | D | K | S | V | Q | L | V | M | E | Y | V | P | L | G | . |
S | L | R | D | Y | L | P | R | H | C | . |
. |
V | G | L | A | Q | L | L | L | F | A | Q | Q | I | C | E | G |
| Template Known Secondary structure |   |
 |  |  |
|
|
| T | T | B |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
| T | T |  | . |  |  |  |  |  | G | G | G | S |
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
947 | . | . | 950 | . | . | . | . | . | . | . | . | . | 960 | . | . | . | . | . | . | . | . | . | 970 | . | . | . | . | . | . | . | |
. | . | 980 | . | . | . | . | . | . | . | |
|
. | . | 990 | . | . | . | . | . | . | . | . | . | 1000 | . | . | . |
|   |
|   |   |
500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | |
|
. | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
| . | . |
|  |  |  |
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
| Query Sequence |   |
M | A | F | L | E | S | H | Q | F | I | H | R | D | L | A | A | R | N | C | L | V | D | S | D | L | S | V | K | V | S | D | F | G | M | T | R | Y | V | L | D | D | Q | Y | V | S | S | V | G | T | K | F | . |
. |
P | V | K | W | S | A | P |
| Query Conservation |   |
|   |   |
|
|   |   |   |   |
|
|   |
|
|   |   |   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
M | A | Y | L | H | A | Q | H | Y | I | H | R | A | L | A | A | R | N | V | L | L | D | N | D | R | L | V | K | I | G | D | F | G | L | A | K | A | V | P | E | G | H | E | Y | Y | R | V | R | E | D | G | D | S | P | V | F | W | Y | A | P |
| Template Known Secondary structure |   |
 |  |  |  |  |  | T | T |  |  |
| S |
|
| S | G | G | G |  |  |  |
| G | G | G |
|  |  |  |
|
|
| T | T |
|  |  |
|
| T | T |
| S |  |  |  |
|
|
|
| S | S | S |
| G | G | G |
|
|  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1007 | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020 | . | . | . | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . |
|   |
|   |   |
558 | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 600 | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
E | V | F | H | Y | F | K | Y | S | S | K | S | D | V | W | A | F | G | I | L | M | W | E | V | F | S | L | G | K | Q | P | Y | D | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | D | N | S | E | V | V | V | K | V | S |
| Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |   |
|   |
|
|   |
|   |
|   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |
|
|
|
| . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
E | C | L | K | E | C | K | F | Y | Y | A | S | D | V | W | S | F | G | V | T | L | Y | E | L | L | T | . |
Y | C | D | S | N | Q | S | P | H | T | K | F | T | E | L | I | G | H | T | Q | G | Q | M | T | V | L | R | L | T | E | L | L | E |
| Template Known Secondary structure |   |
 |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | T | T |
| T | T | S | S |  |  |  |  |  |  |  |  |  |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1067 | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . | . | . | . | . | . | . | . | 1090 | . | . | |
. | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | . |
|   |
|   |   |
603 | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Q | G | H | R | L | Y | R | P | Q | L | A | S | D | T | I | Y | Q | I | M | Y | S | C | W | H | E | L | P | E | K | R | P | T | F | Q | Q | L | L | S | A | I | E | P | L | R | E | Q |
| Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |   |
|   |   |   |   |   |   |
| Template Sequence |   |
R | G | E | R | L | P | R | P | D | R | C | P | C | E | I | Y | H | L | M | K | N | C | W | E | T | E | A | S | F | R | P | T | F | Q | N | L | V | P | I | L | Q | T | A | Q | E | K |
| Template Known Secondary structure |   |
 | T |
|
|
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1126 | . | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140 | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . |
|   |