Return to main results Retrieve Phyre Job Id

Job DescriptionP97504
Confidence100.00%DateWed Jul 10 14:16:15 BST 2013
Rank88Aligned Residues333
% Identity24%Templatec3o96A_
PDB info PDB header:transferaseChain: A: PDB Molecule:rac-alpha serine/threonine-protein kinase; PDBTitle: crystal structure of human akt1 with an allosteric inhibitor
Resolution2.70 Å
Model Dimensions (Å)X:62.822 Y:59.449 Z:44.877

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.........30.........40.........50.........60.
Predicted Secondary structure 





























Query SS confidence 



























































Query Sequence  ESKSILEELLLKKSQQKKKMSPNNYKERLFVLTKTSLSYYEYDKMKRGSRKGSIEIKKIR
Query Conservation             

          


 
 


    
 

             
 
  
 
Alig confidence 














.....





























..







Template Conservation         
 
 
   .....    

 
   
                  .. 
    
 
Template Sequence  DVAIVKEGWLHKRGE. . . . . YIKTWRPRYFLLKNDGTFIGYKERPQDVEA. . PLNNFSVA
Template Known Secondary structure 



S.....SS

TTSBSS

S



..

GGGB
T
Template Predicted Secondary structure 




.....















..





Template SS confidence 



























































   3......10....... ..20.........30.........40....... ..50.....
 
   62.......70.........80....... ..90.........100.........110.........120
Predicted Secondary structure 














.








Query SS confidence 

























.
































Query Sequence  CVEKVNLEEQTPVERQYPFQIVYKDG. LLYVYASNEESRCQWLKALQKEIRGNPHLLIKY
Query Conservation   

               
 
     .  
  
    
   

  
              
Alig confidence 









....











.




























....
Template Conservation            ....    
 
                    
              ....
Template Sequence  QCQLMKTERP. . . . RPNTFIIRCLQWTTVIERTFTPEEREEWTTAIQTVADGLKKQ. . . .
Template Known Secondary structure  T



B

SS....SSS
BTT

TTGGGTT
....
Template Predicted Secondary structure 





....



















....
Template SS confidence 



























































   5960........ .70.........80.........90.........100.........110
 
   121........130.........140.........150.........160.........170.........180
Predicted Secondary structure 



























































Query SS confidence 



























































Query Sequence  HSGFFVDGKFLCCQQSCKAAPGCTLWEAYADLHIAISDEKHRAPTFPERLLKIPRAVPVL
Query Conservation 
      
   
         

             
      
  
      
   
  
Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
Template Predicted Secondary structure  ............................................................
Template SS confidence 



























































  
 
   181........190.........200.........210.........220.........230.........240
Predicted Secondary structure 



























































Query SS confidence 



























































Query Sequence  KMDASSSGAILPQYDSYSKKSCGSQPTSNIRYIPREDCPDWWQVRKLKSEEDIACSNQLE
Query Conservation       

        
                            
         

    
Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
Template Predicted Secondary structure  ............................................................
Template SS confidence 



























































  
 
   241........250.........260.........270.........280.........290.........300
Predicted Secondary structure 












































Query SS confidence 



























































Query Sequence  RNIASHSTSKMSWGFPESSSSEEEENLHAYDWFAGNISRSQSEQLLRQKGKEGAFMVRNS
Query Conservation                   
            

  
 


  

 

     

 



 
Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
Template Predicted Secondary structure  ............................................................
Template SS confidence 



























































  
 
   301........310.........320.........330.........340.........350.........360
Predicted Secondary structure 








































Query SS confidence 



























































Query Sequence  SQMGMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAGM
Query Conservation 
  
   

             

  
               
 

 


          
Template Conservation  ............................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............................................................
Template Predicted Secondary structure  ............................................................
Template SS confidence 



























































  
 
   361........370.........380.........390.........400.........410... ......
Predicted Secondary structure 





























.


Query SS confidence 




















































.





Query Sequence  ITRLRHPVSTKANKVPVSVALGSGIWELKREEITLLKELGNGQFGVVQLGQWK. GQYDVA
Query Conservation                             
          

 
 

 
      .    

Alig confidence  ...........................

























.





Template Conservation  ...........................     
     

 
 

 

           
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . VTMNEFEYLKLLGKGTFGKVILVKEKATGRYYA
Template Known Secondary structure  ...........................

TTSTTTTT

Template Predicted Secondary structure  ...........................












Template SS confidence 



























































   145....150.........160.........170.......
 
   420.........430.........440.........450.........460.........470.........
Predicted Secondary structure 





















Query SS confidence 



























































Query Sequence  VKMIKEGAMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKS
Query Conservation 

              
   
  
 
 


 
           

 
    
 
   
  
Alig confidence 




......
















































Template Conservation 

   ......
    
  

  
 




             



      
      
Template Sequence  MKILK. . . . . . KEVIVANRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR
Template Known Secondary structure  ......GGGS



GGGTS

TTB


SS

SS
B
Template Predicted Secondary structure  ......



















Template SS confidence 



























































   178.180.. .......190.........200.........210.........220.........230.
 
   480.........490.........500..... ....510.........520.........530........
Predicted Secondary structure 





.

















Query SS confidence 

























.
































Query Sequence  HGKGLESCQLLEMCYDVCEGMAFLES. HQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVL
Query Conservation                  
   
  

 .   

 

   



      

 


      
Alig confidence 


.





















.































.
Template Conservation     .            
            
                      

     .
Template Sequence  ERV. FSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEP.
Template Known Secondary structure  SS.

TS







GGG
TTS




SS


.
Template Predicted Secondary structure 


.























.
Template SS confidence 



























































   242.. .....250.........260.........270.........280.........290.........
 
   539540.........550.........560.........570.........580.........590........
Predicted Secondary structure 

























Query SS confidence 



























































Query Sequence  DDQYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVV
Query Conservation                   


          




 
  
 

 
 
  
          
Alig confidence  ..............






























.













Template Conservation  ..............                 

 


 

 

  .
  

         
Template Sequence  . . . . . . . . . . . . . . EYLAPEVLEDNDYGRAVDWWGLGVVMYEMMC. GRLPFYNQDHEKLF
Template Known Secondary structure  ..............
SS
TT



T.SS
SS

SS
Template Predicted Secondary structure  ..............

















.








Template SS confidence 



























































   314.....320.........330.........340.... .....350........
 
   599600.........610.........620.........630.. .......640
Predicted Secondary structure 
















.....

Query SS confidence 

































. . . . .







Query Sequence  VKVSQGHRLYRPQLASDTIYQIMYSCWHELPEKR. . . . . PTFQQLLS
Query Conservation    
        
         

  
    
  
.....

   
  
Alig confidence 






.

























.....







Template Conservation    
    .       
    


   
  

  
     

  
 
 
Template Sequence  ELILMEE. IRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQ
Template Known Secondary structure 

.



TT

T
SSTTTSTT
STTTT
Template Predicted Secondary structure 


.



















Template SS confidence 














































   359360..... ....370.........380.........390.........400....
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions
Phyre2 is part of Genome3D