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Job DescriptionP97504
Confidence100.00%DateWed Jul 10 14:16:15 BST 2013
Rank48Aligned Residues257
% Identity33%Templatec3lxkA_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   388.390.........400.........410... ......420....... ..430.........440.
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Query Sequence  LKREEITLLKELGNGQFGVVQLGQWK. . . . . GQYDVAVKMIKEGA. MSEDEFFQEAQTMM
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Template Sequence  FEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILK
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GGGTT
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   817..820.........830.........840.........850.........860.........870......
 
   442.......450....... ..460.........470.........480.........490.........
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Query Sequence  KLSHPKLVKFYGVCSK. . KYPIYIVTEYITNGCLLNYLKSHGKGLESCQLLEMCYDVCEG
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Template Sequence  ALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLYSSQICKG
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   877..880.........890.........900.........910.........920.........930......
 
   500.........510.........520.........530......... 540.........550.......
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Query Sequence  MAFLESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLD. . DQYVSSVGTKFPVKWSAP
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Template Sequence  MEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAP
Template Known Secondary structure  TT
S

SGGGTT


TT


TT
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   937..940.........950.........960.........970.........980.........990......
 
   558.560.........570.........580.........590. ........600.......
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Query Sequence  EVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDL. . . . . . . . . . YDNSEVVVKVSQGHRL
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Template Sequence  ESLSDNIFSRQSDVWSFGVVLYELFT. YCDKSCSPSAEFLRMMVPALSRLLELLEEGQRL
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T.TT
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   997..1000.........1010.........1020.. .......1030.........1040.........1050.....
 
   608.610.........620.........630.........640.....
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Query Sequence  YRPQLASDTIYQIMYSCWHELPEKRPTFQQLLSAIEPL
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Template Sequence  PAPPACPAEVHELMKLCWAPSPQDRPSFSALGPQLDML
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TT

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   1061........1070.........1080.........1090........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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