|   |   |
387 | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | |
440 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| Query Sequence |   |
E | L | K | R | E | E | I | T | L | L | K | E | L | G | N | G | Q | F | G | V | V | Q | L | G | Q | W | K | G | Q | Y | D | V | A | V | K | M | I | K | E | G | A | M | S | E | D | E | F | F | Q | E | A | Q | T | . |
M | M | K | L | S | H |
| Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . |
|   |   |
|   |
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|   |   |
|   |
|
|   |   |   |   | . |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |
| Template Sequence |   |
Q | L | G | S | K | L | V | Y | V | H | H | L | L | G | E | G | A | F | A | Q | V | Y | E | A | T | Q | . |
N | K | Q | K | F | V | L | K | V | Q | K | P | A | N | P | W | E | F | Y | I | G | T | Q | L | M | E | R | L | K | P | S | M | Q |
| Template Known Secondary structure |   |
 |
| S | S | S |  |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |
| . |
|
|
|
|  |  |  |  |  |  | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| G | G | G | G |
| Template Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
781 | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | |
. | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
446 | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | |
|
|
|
480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
P | K | L | V | K | F | Y | G | V | C | S | K | K | Y | P | I | Y | I | V | T | E | Y | I | T | N | G | C | L | L | N | Y | L | K | S | . |
. |
. |
. |
H | G | K | G | L | E | S | C | Q | L | L | E | M | C | Y | D | V | C | E | G | M | A |
| Query Conservation |   |
  |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |
| Template Sequence |   |
H | M | F | M | K | F | Y | S | A | H | L | F | Q | N | G | S | V | L | V | G | E | L | Y | S | Y | G | T | L | L | N | A | I | N | L | Y | K | N | T | P | E | K | V | M | P | Q | G | L | V | I | S | F | A | M | R | M | L | Y | M | I | E |
| Template Known Secondary structure |   |
G | G | B |
|
|  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |
|
|
|
| S |
| B |  |  |  |  |  |  |  |  |  | T | S | T | T |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
847 | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | . | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . | . | . | . | . | . | . | 890 | . | . | . | . | . | . | . | . | . | 900 | . | . | . | . | . | . |
|   |
|   |   |
502 | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | |
540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |
|
|
|
|
|  |  |  |  |  |  | . | . | . | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
| . |
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
F | L | E | S | H | Q | F | I | H | R | D | L | A | A | R | N | C | L | V | . |
. |
. |
. |
. |
D | S | D | L | S | V | K | V | S | D | F | G | M | T | R | Y | V | L | D | . |
D | Q | Y | V | S | S | V | G | T | K | F | P | V | K | W | S |
| Query Conservation |   |
  |
|
|   |   |   |   |
|
|   |
|
|   |   |   |
|
|
|
| . | . | . | . | . |   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|
|   |   |   |
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
| Template Sequence |   |
Q | V | H | D | C | E | I | I | H | G | D | I | K | P | D | N | F | I | L | G | N | G | F | L | E | Q | S | A | G | L | A | L | I | D | L | G | Q | S | I | D | M | K | L | F | P | K | G | T | I | F | T | A | K | C | E | T | S | G | F | Q |
| Template Known Secondary structure |   |
 |  |  | T | T | T |  |  |
|
|
|
| S | G | G | G |  |  |  |
| G | G | G | T |
|
|
| T | T |  |  |  |
|
|
| T | T |
|  |  | G | G | G | S |
| T | T |  |  |  |
|
| S | S |
| T | T | S |
|
|
| Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
907 | . | . | 910 | . | . | . | . | . | . | . | . | . | 920 | . | . | . | . | . | . | . | . | . | 930 | . | . | . | . | . | . | . | . | . | 940 | . | . | . | . | . | . | . | . | . | 950 | . | . | . | . | . | . | . | . | . | 960 | . | . | . | . | . | . |
|   |
|   |   |
556 | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
A | P | E | V | F | H | Y | F | K | Y | S | S | K | S | D | V | W | A | F | G | I | L | M | W | E | V | F | S | L | G | K | Q | P | Y | D | L | Y | D | N | S | E | V | V | V | K | V | S | Q | G | H | R | L | Y | R | P | Q | L | A | S | D |
| Query Conservation |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|
|   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|
|   |
|
|   |
|
|
|   | . |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
C | V | E | M | L | S | N | K | P | W | N | Y | Q | I | D | Y | F | G | V | A | A | T | V | Y | C | M | L | F | . |
G | T | Y | M | K | V | K | N | E | G | . |
. |
. |
. |
. |
G | E | C | K | P | E | G | L | F | R | R | L | P | H | L | D |
| Template Known Secondary structure |   |
|  |  |  |  | T | T |
|
| B | S | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
|
|
|  |  |  |  | T | . | . | . | . | . | T |  |  |  |  |
| S |
|
| T | T |
| S | S |  |  |
| Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
973 | . | . | . | . | . | . | 980 | . | . | . | . | . | . | . | . | . | 990 | . | . | . | . | . | . | . | . | . | 1000 | |
. | . | . | . | . | . | . | . | . | 1010 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 1020 | . | . | . | . | . | . |
|   |
|   |   |
616 | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | |
. | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
T | I | Y | Q | I | M | Y | S | C | W | H | E | L | P | E | K | R | . |
P | T | F | Q | Q | L | L | S | A | I | E | P | L | R | E | Q | D |
| Query Conservation |   |
  |   |   |   |
|
|   |   |
|   |   |   |   |
|   |   |
| . |
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
| Template Sequence |   |
M | W | N | E | F | F | H | V | M | L | N | I | P | D | C | H | H | L | P | S | L | D | L | L | R | Q | K | L | K | K | V | F | Q | Q | H |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
| T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
1027 | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . |
|   |