|   |   |
389 | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | |
. | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | |
. | . | . |
| Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
| Query Sequence |   |
K | R | E | E | I | T | L | L | K | E | L | G | N | G | Q | F | G | V | V | Q | L | G | Q | W | K | . |
G | Q | Y | D | V | A | V | K | M | I | K | E | G | A | M | S | E | D | E | F | F | Q | E | A | Q | T | M | M | K | L | . |
S | H | P |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
| . |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
| Template Conservation |   |
  |   |
|   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |
| Template Sequence |   |
P | A | G | I | F | E | L | V | E | L | V | G | N | G | T | Y | G | Q | V | Y | K | G | R | H | V | K | T | G | Q | L | A | A | I | K | V | M | D | V | T | G | D | E | E | E | E | I | K | Q | E | I | N | M | L | K | K | Y | S | H | H | R |
| Template Known Secondary structure |   |
| T | T | T |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |
|
| S | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | T |
| Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
21 | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
|   |
|   |   |
447 | . | . | 450 | . | . | . | . | . | . | . | . | . | |
|
|
|
460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | |
. | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . |
| Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
|
| . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
| . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | L | V | K | F | Y | G | V | C | S | K | K | Y | . |
. |
. |
. |
P | I | Y | I | V | T | E | Y | I | T | N | G | C | L | L | N | Y | L | K | S | H | . |
G | K | G | L | E | S | C | Q | L | L | E | M | C | Y | D | V | C | E | G | M | A |
| Query Conservation |   |
|
|
|   |
|   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
| Template Sequence |   |
N | I | A | T | Y | Y | G | A | F | I | K | K | N | G | M | D | D | Q | L | W | L | V | M | E | F | C | G | A | G | S | V | T | D | L | I | K | N | T | K | G | N | T | L | K | E | E | W | I | A | Y | I | C | R | E | I | L | R | G | L | S |
| Template Known Secondary structure |   |
T | B |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| T | T |  |  |  |  |  |  |  |  |  | S | G | G | G |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 |
|   |
|   |   |
502 | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . |
| Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
F | L | E | S | H | Q | F | I | H | R | D | L | A | A | R | N | C | L | V | D | S | D | L | S | V | K | V | S | D | F | G | M | T | R | Y | V | L | D | D | Q | Y | V | S | S | V | G | T | K | F | P | V | K | W | S | A | P | E | V | F | H |
| Query Conservation |   |
  |
|
|   |   |   |   |
|
|   |
|
|   |   |   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
|   |   |   |
| Template Sequence |   |
H | L | H | Q | H | K | V | I | H | R | D | I | K | G | Q | N | V | L | L | T | E | N | A | E | V | K | L | V | D | F | G | V | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | G | T | P | Y | W | M | A | P | E | V | I | A |
| Template Known Secondary structure |   |
 |  |  |  | T | T |
|
|
|
|
|
| S | G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
|
| T | T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
| G | G | G |
|
|  |  |  |  |
|
| Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
143 | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 180 | . | . | . | . | . | . | . | . |
|   |
|   |   |
562 | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | |
. | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | F | K | Y | S | S | K | S | D | V | W | A | F | G | I | L | M | W | E | V | F | S | L | G | K | Q | P | Y | D | L | Y | D | N | S | E | V | V | V | K | V | S | Q | G | H | R | . |
L | Y | R | P | Q | L | A | S | D | T | I | Y | Q | I |
| Query Conservation |   |
  |   |   |   |   |   |   |
|
|
|
|
|   |
|   |   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
| Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
. | . | . |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|
| . |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
| Template Sequence |   |
. |
. |
. |
Y | D | F | K | S | D | L | W | S | L | G | I | T | A | I | E | M | A | E | . |
G | A | P | P | L | C | D | M | H | P | M | R | A | L | F | L | I | P | R | N | P | A | P | R | L | K | S | K | K | W | S | K | K | F | Q | S | F |
| Template Known Secondary structure |   |
. | . | . |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | S | S |
| T | T | T | T | S |
|  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|
| S |
| S |
| S |
|  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
. | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | |
. | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . |
|   |
|   |   |
621 | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 |
| Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
M | Y | S | C | W | H | E | L | P | E | K | R | P | T | F | Q | Q | L | L | S |
| Query Conservation |   |
|   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |
|
|
|   |
| Template Sequence |   |
I | E | S | C | L | V | K | N | H | S | Q | R | P | A | T | E | Q | L | M | K |
| Template Known Secondary structure |   |
 |  |  |  |
|
| S | S | G | G | G | S |
|
|  |  |  |  |  | T |
| Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
266 | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . |
|   |