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Job DescriptionP97504
Confidence100.00%DateWed Jul 10 14:16:15 BST 2013
Rank125Aligned Residues239
% Identity22%Templatec2r7bA_
PDB info PDB header:signaling protein, transferaseChain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   389390.........400.........410... ......420.... .....430.........440...
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Query Sequence  KREEITLLKELGNGQFGVVQLGQWK. GQYDVAVKMIK. . . . EGAMSEDEFFQEAQTMMKL
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Template Sequence  RPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRL
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GGG
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TT
T
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   78.80.........90.........100.........110.........120.........130.......
 
   444.....450.........460.........470.........480.........490.........500...
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Query Sequence  SHPKLVKFYGVCSKKYPIYIVTEYITNGCLLNYLKSHGKGLESCQLLEMCYDVCEGMAFL
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Template Sequence  DHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGS. FDETCTRFYTAEIVSALEYL
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   138.140.........150.........160.........170...... ...180.........190......
 
   504.....510.........520.........530.........540.........550.........560...
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Query Sequence  ESHQFIHRDLAARNCLVDSDLSVKVSDFGMTRYVLDDQYVSSVGTKFPVKWSAPEVFHYF
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Template Sequence  HGKGIIHRDLKPENILLNEDMHIQITDFGTAKVL. . . . . . . . . . FVGTAQYVSPELLTEK
Template Known Secondary structure  TT




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   197..200.........210.........220.........230 .........240......
 
   564.....570.........580.........590.........600.........610.........620...
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Query Sequence  KYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSEVVVKVSQGHRLYRPQLASDTIYQIMYS
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Template Sequence  SACKSSDLWALGCIIYQLVA. GLPPFRAGNEYLIFQKIIKLE. YDFPEKFFPKARDLVEK
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   258.260.........270....... ..280.........290........ .300.........310.....
 
   624.....630.........640
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Query Sequence  CWHELPEKRPTFQQLLS
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Template Sequence  LLVLDATKRLGCEEMEG
Template Known Secondary structure  TS
SSTTSSTTSGGGTT
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   316...320.........330..
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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