|   |   |
381 | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | |
|
. | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
| . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  | . | . |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
| Query Sequence |   |
L | G | S | G | I | W | E | L | K | R | E | E | I | T | L | L | K | E | L | G | N | G | Q | F | G | V | V | Q | L | G | Q | W | K | . |
. |
. |
. |
. |
G | Q | Y | D | V | A | V | K | M | I | K | E | G | A | M | S | E | . |
. |
D | E | F |
| Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   | . | . |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
| Template Conservation |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
P | E | D | P | K | W | E | F | P | R | D | K | L | T | L | G | K | P | L | G | E | G | A | F | G | Q | V | V | M | A | E | A | V | G | I | D | K | D | K | P | V | T | V | A | V | K | M | L | K | D | D | A | T | E | K | D | L | S | D | L |
| Template Known Secondary structure |   |
|
|
| T | T | T | B |
|
| G | G | G |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  | T | T |
| S | T | T |
|
|
|  |  |  |  |  |  |
|
| T | T |
|
|  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
469 | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . |
|   |
|   |   |
434 | . | . | . | . | . | 440 | . | . | . | |
. | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | |
|
|
|
|
|
. | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . |
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
| Query Sequence |   |
F | Q | E | A | Q | T | M | M | K | L | . |
S | H | P | K | L | V | K | F | Y | G | V | C | S | K | K | Y | P | I | Y | I | V | T | E | Y | I | T | N | G | C | L | L | N | Y | L | K | S | H | G | K | G | . |
. |
. |
. |
. |
. |
L | E | S |
| Query Conservation |   |
  |   |
|   |   |   |
|   |   |
| . |   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
| Template Conservation |   |
  |   |
|
|   |   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
| Template Sequence |   |
V | S | E | M | E | M | M | K | M | I | G | K | H | K | N | I | I | N | L | L | G | A | C | T | Q | D | G | P | L | Y | V | I | V | E | Y | A | S | K | G | N | L | R | E | Y | L | R | A | R | R | P | P | G | M | E | S | Y | Q | M | T | F |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
| T | T | B |
|
|  |  |  |  |  |
| S | S | S |
|
|  |  |  |  |  |
|
| T | T |
| B |  |  |  |  |  |  | T | T | S |
| T | T |
|
|
|
|
|
|
|  |
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
532 | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . |
|   |
|   |   |
487 | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
C | Q | L | L | E | M | C | Y | D | V | C | E | G | M | A | F | L | E | S | H | Q | F | I | H | R | D | L | A | A | R | N | C | L | V | D | S | D | L | S | V | K | V | S | D | F | G | M | T | R | Y | V | L | D | D | Q | Y | V | S | S | V |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |
|
|   |
|
|   |   |   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
K | D | L | V | S | C | T | Y | Q | L | A | R | G | M | E | Y | L | A | S | Q | K | C | I | H | R | D | L | A | A | R | N | V | L | V | T | E | N | N | V | M | K | I | A | D | F | G | L | A | R | D | I | N | N | I | D | K | K | T | T | N |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
| S | G | G | G |  |  |  |
| T | T |
|
|  |  |  |
|
|
| T | T |
|  |  |
| T | T | T |
|
|
|
| S |
|
| Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
601 | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 |
|   |
|   |   |
547 | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
G | T | K | F | P | V | K | W | S | A | P | E | V | F | H | Y | F | K | Y | S | S | K | S | D | V | W | A | F | G | I | L | M | W | E | V | F | S | L | G | K | Q | P | Y | D | L | Y | D | N | S | E | V | V | V | K | V | S | Q | G | H | R |
| Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
| Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  | . |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
| Template Sequence |   |
G | . |
R | L | P | V | K | W | M | A | P | E | A | L | F | D | R | V | Y | T | H | Q | S | D | V | W | S | F | G | V | L | M | W | E | I | F | T | L | G | G | S | P | Y | P | G | I | P | V | E | E | L | F | K | L | L | K | E | G | H | R |
| Template Known Secondary structure |   |
| . |
|
|
| G | G | G |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
| S | S | T | T |
|
|  |  |  |  |  |  |  |  |  |  | T |
|
|
| Template Predicted Secondary structure |   |
| . |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
663 | |
. | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . |
|   |
|   |   |
607 | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | Y | R | P | Q | L | A | S | D | T | I | Y | Q | I | M | Y | S | C | W | H | E | L | P | E | K | R | P | T | F | Q | Q | L | L | S | A | I | E | P | L | R | E |
| Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|
|
|   |   |
|
|
|   |   |
|   |   |
|
|   |
| Template Sequence |   |
M | D | K | P | A | N | C | T | N | E | L | Y | M | M | M | R | D | C | W | H | A | V | P | S | Q | R | P | T | F | K | Q | L | V | E | D | L | D | R | I | L | T |
| Template Known Secondary structure |   |
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  | T |
| S | S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
722 | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . |
|   |