Job Description P97504 Confidence 100.00% Date Wed Jul 10 14:16:15 BST 2013 Rank 6 Aligned Residues 421 % Identity 34% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å Model Dimensions (Å) X:69.043 Y:72.221 Z:50.014

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		190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.		.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.
Predicted Secondary structure																																							.
Query SS confidence																																							.
Query Sequence		I	L	P	Q	Y	D	S	Y	S	K	K	S	C	G	S	Q	P	T	S	N	I	R	Y	I	P	R	E	D	C	P	D	W	W	Q	V	R	K	.	L	K	S	E	E	D	I	A	C	S	N	Q	L	E	R	N	I	A	S	H	S	T
Query Conservation																																							.
Alig confidence																																							.																	.	.	.	.	.	.
Template Conservation																																																								.	.	.	.	.	.
Template Sequence		V	V	A	L	Y	D	Y	E	A	I	H	H	E	D	L	S	F	Q	K	G	D	Q	M	V	V	L	E	E	S	G	E	W	W	K	A	R	S	L	A	T	R	K	E	G	Y	I	P	S	N	Y	V	A	R	V	.	.	.	.	.	.
Template Known Secondary structure					S	S		B				S	S	S	B			B		T	T										T	T							T	T	T								G	G	G				T	.	.	.	.	.	.
Template Predicted Secondary structure																																																								.	.	.	.	.	.
Template SS confidence
		62	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.
		249	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290		.	.	.	.	.	.	.	.	.	300		.	.	.	.	.	.
Predicted Secondary structure																																												.											.
Query SS confidence																																												.											.
Query Sequence		S	K	M	S	W	G	F	P	E	S	S	S	S	E	E	E	E	N	L	H	A	Y	D	W	F	A	G	N	I	S	R	S	Q	S	E	Q	L	L	R	Q	K	G	.	K	E	G	A	F	M	V	R	N	S	.	S	Q	M	G	M	Y
Query Conservation																																												.											.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																											.											.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D	S	L	E	T	E	E	W	F	F	K	G	I	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	Y
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T	S	G	G	G	S	T	T			T	T											T	S	T	T			T	T								S	S	S	T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
																		116	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.
		307	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	V	S	L	F	S	K	A	V	N	D	K	K	G	T	V	K	H	Y	H	V	H	T	N	A	E	N	K	L	Y	L	A	E	N	Y	C	F	D	S	I	P	K	L	I	H	Y	H	Q	H	N	S	A	G	M	I	T	R	L	R	H
Query Conservation
Alig confidence									.
Template Conservation									.
Template Sequence		S	L	S	V	R	D	Y	.	D	P	R	Q	G	D	T	V	K	H	Y	K	I	R	T	L	D	N	G	G	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L	C	Q	K	L	S	V
Template Known Secondary structure									.		T	T	T										B			S	T	T				S	S	T	T	S			S	S								T	T	S	S		S	S		S	S				S
Template Predicted Secondary structure									.
Template SS confidence
		160	.	.	.	.	.	.		.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.
		367	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	V	S	T	K	A	N	K	V	P	V	S	V	A	L	G	S	G	I	W	E	L	K	R	E	E	I	T	L	L	K	E	L	G	N	G	Q	F	G	V	V	Q	L	G	Q	W	K	G	Q	Y	D	V	A	V	K	M	I	K	E	G
Query Conservation
Alig confidence												.	.	.	.
Template Conservation												.	.	.	.
Template Sequence		P	C	M	S	S	K	P	Q	K	P	.	.	.	.	W	E	K	D	A	W	E	I	P	R	E	S	L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	K	H	T	K	V	A	V	K	T	M	K	P	G
Template Known Secondary structure		B										.	.	.	.			T	T		S	B			G	G	G											T	T									T	T	T
Template Predicted Secondary structure												.	.	.	.
Template SS confidence
		219	220	.	.	.	.	.	.	.	.					.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.
		427	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.		.	.	.
Predicted Secondary structure																																																										.
Query SS confidence																																																										.
Query Sequence		A	M	S	E	D	E	F	F	Q	E	A	Q	T	M	M	K	L	S	H	P	K	L	V	K	F	Y	G	V	C	S	K	K	Y	P	I	Y	I	V	T	E	Y	I	T	N	G	C	L	L	N	Y	L	K	S	H	G	K	.	G	L	E
Query Conservation																																																										.
Alig confidence																															.																											.
Template Conservation																															.
Template Sequence		S	M	S	V	E	A	F	L	A	E	A	N	V	M	K	T	L	Q	H	D	K	L	V	K	L	H	A	V	V	.	T	K	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	S	K	Q	P
Template Known Secondary structure		S	S														T				T	T	B								.		S	S	S									T	T		B							S	T	T	G	G	G
Template Predicted Secondary structure																															.
Template SS confidence
		275	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.		.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.
		486	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	C	Q	L	L	E	M	C	Y	D	V	C	E	G	M	A	F	L	E	S	H	Q	F	I	H	R	D	L	A	A	R	N	C	L	V	D	S	D	L	S	V	K	V	S	D	F	G	M	T	R	Y	V	L	D	D	Q	Y	V	S	S
Query Conservation
Alig confidence																																																				.	.	.	.	.	.	.	.	.	.
Template Conservation																																																				.	.	.	.	.	.	.	.	.	.
Template Sequence		L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E	Q	R	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	A	S	L	V	C	K	I	A	D	F	G	L	A	R	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure																						T	T				S			S	G	G	G					T	T								T	T	G	G	G	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																				.	.	.	.	.	.	.	.	.	.
Template SS confidence
		334	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.
		546	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	G	T	K	F	P	V	K	W	S	A	P	E	V	F	H	Y	F	K	Y	S	S	K	S	D	V	W	A	F	G	I	L	M	W	E	V	F	S	L	G	K	Q	P	Y	D	L	Y	D	N	S	E	V	V	V	K	V	S	Q	G	H
Query Conservation
Alig confidence		.	.	.
Template Conservation		.	.	.
Template Sequence		.	.	.	V	I	P	I	K	W	T	A	P	E	A	I	N	F	G	S	F	T	I	K	S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P	E	V	I	R	A	L	E	R	G	Y
Template Known Secondary structure		.	.	.	T			G	G	G	S																												T	T	T			S	S	T	T												T	T
Template Predicted Secondary structure		.	.	.
Template SS confidence
					384	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440
		606	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	L	Y	R	P	Q	L	A	S	D	T	I	Y	Q	I	M	Y	S	C	W	H	E	L	P	E	K	R	P	T	F	Q	Q	L	L	S	A	I	E	P	L	R	E	Q	D	K	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	M	M	R	C	W	K	N	R	P	E	E	R	P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A	T	E	S
Template Known Secondary structure							T	T													T		S	S	G	G	G	S												T	T	T	S		G	G	G
Template Predicted Secondary structure
Template SS confidence
		454	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.