Job Description P97504 Confidence 100.00% Date Wed Jul 10 14:16:15 BST 2013 Rank 2 Aligned Residues 433 % Identity 36% Template c1oplA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase Resolution 3.42 Å Model Dimensions (Å) X:61.655 Y:71.780 Z:52.119

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		187	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.			.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.
Predicted Secondary structure																															.	.
Query SS confidence																															.	.
Query Sequence		S	G	A	I	L	P	Q	Y	D	S	Y	S	K	K	S	C	G	S	Q	P	T	S	N	I	R	Y	I	P	R	.	.	E	D	C	P	D	W	W	Q	V	R	K	L	K	S	E	E	D	I	A	C	S	N	Q	L	E	R	N	I	A
Query Conservation																															.	.
Alig confidence																															.	.												.																.	.
Template Conservation																																												.																.	.
Template Sequence		P	N	L	F	V	A	L	Y	D	F	V	A	S	G	D	N	T	L	S	I	T	K	G	E	K	L	R	V	L	G	Y	N	H	N	G	E	W	C	E	A	Q	T	.	K	N	G	Q	G	W	V	P	S	N	Y	I	T	P	V	.	.
Template Known Secondary structure		T	T					S	S		B				S	T	T	B			B		T	T										T	T	S	S							.	S	S							G	G	G				S	.	.
Template Predicted Secondary structure																																												.																.	.
Template SS confidence
		82	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.		.	.	.	.	.	.	130	.	.	.	.	.	.	.	.
		245	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300		.	.	.
Predicted Secondary structure																																																										.
Query SS confidence																																																										.
Query Sequence		S	H	S	T	S	K	M	S	W	G	F	P	E	S	S	S	S	E	E	E	E	N	L	H	A	Y	D	W	F	A	G	N	I	S	R	S	Q	S	E	Q	L	L	R	Q	K	G	K	E	G	A	F	M	V	R	N	S	.	S	Q	M
Query Conservation																																																										.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																									.												.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																									.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	N	S	L	E	K	H	S	W	Y	H	G	P	V	S	R	N	A	A	E	Y	L	L	S	S	.	G	I	N	G	S	F	L	V	R	E	S	E	S	S	P
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S	S	G	G	G	S	T	T														G	G	G	.			T	T								S	S	S	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																									.
Template SS confidence
																						139	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.		.	.	.	.	.	.	.	170	.	.	.	.	.	.	.
		304	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	M	Y	T	V	S	L	F	S	K	A	V	N	D	K	K	G	T	V	K	H	Y	H	V	H	T	N	A	E	N	K	L	Y	L	A	E	N	Y	C	F	D	S	I	P	K	L	I	H	Y	H	Q	H	N	S	A	G	M	I	T	R
Query Conservation
Alig confidence										.	.	.	.	.	.
Template Conservation										.	.	.	.	.	.
Template Sequence		G	Q	R	S	I	S	L	R	.	.	.	.	.	.	Y	E	G	R	V	Y	H	Y	R	I	N	T	A	S	D	G	K	L	Y	V	S	S	E	S	R	F	N	T	L	A	E	L	V	H	H	H	S	T	V	A	D	G	L	I	T	T
Template Known Secondary structure		T								.	.	.	.	.	.		T	T											T	T	S				S	S	T	T	S		B	S	S									T	T			T	T	S	S	S
Template Predicted Secondary structure										.	.	.	.	.	.
Template SS confidence
		178	.	180	.	.	.	.	.							.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.
		364	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.		.	.	.	.	.	420	.	.
Predicted Secondary structure																																																					.
Query SS confidence																																																					.
Query Sequence		L	R	H	P	V	S	T	K	A	N	K	V	P	V	S	V	A	L	G	S	G	I	W	E	L	K	R	E	E	I	T	L	L	K	E	L	G	N	G	Q	F	G	V	V	Q	L	G	Q	W	K	G	.	Q	Y	D	V	A	V	K	M
Query Conservation																																																					.
Alig confidence																																																					.
Template Conservation
Template Sequence		L	H	Y	P	A	P	K	R	N	K	P	T	V	Y	G	V	S	P	N	Y	D	K	W	E	M	E	R	T	D	I	T	M	K	H	K	L	G	G	G	Q	Y	G	E	V	Y	E	G	V	W	K	K	Y	S	L	T	V	A	V	K	T
Template Known Secondary structure										S					S	S	S		S	S	S	S			B			G	G	G							S	G	G	G	T	T	S	S							G	G	G	T
Template Predicted Secondary structure
Template SS confidence
		232	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.
		423	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	K	E	G	A	M	S	E	D	E	F	F	Q	E	A	Q	T	M	M	K	L	S	H	P	K	L	V	K	F	Y	G	V	C	S	K	K	Y	P	I	Y	I	V	T	E	Y	I	T	N	G	C	L	L	N	Y	L	K	S	H	G	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	K	E	D	T	M	E	V	E	E	F	L	K	E	A	A	V	M	K	E	I	K	H	P	N	L	V	Q	L	L	G	V	C	T	R	E	P	P	F	Y	I	I	T	E	F	M	T	Y	G	N	L	L	D	Y	L	R	E	C	N	R
Template Known Secondary structure				S	S	S	S																		T	T	B									S	S	S	S									T	T		B								S		T
Template Predicted Secondary structure
Template SS confidence
		292	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.
			483	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.
Predicted Secondary structure		.
Query SS confidence		.
Query Sequence		.	G	L	E	S	C	Q	L	L	E	M	C	Y	D	V	C	E	G	M	A	F	L	E	S	H	Q	F	I	H	R	D	L	A	A	R	N	C	L	V	D	S	D	L	S	V	K	V	S	D	F	G	M	T	R	Y	V	L	D	D	Q
Query Conservation		.
Alig confidence		.
Template Conservation
Template Sequence		Q	E	V	N	A	V	V	L	L	Y	M	A	T	Q	I	S	S	A	M	E	Y	L	E	K	K	N	F	I	H	R	N	L	A	A	R	N	C	L	V	G	E	N	H	L	V	K	V	A	D	F	G	L	S	R	L	M	T	G	D	T
Template Known Secondary structure		T	T	S																						T	T				S			S	G	G	G					G	G	G							T	T						T	T
Template Predicted Secondary structure
Template SS confidence
		352	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.
		542	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	V	S	S	V	G	T	K	F	P	V	K	W	S	A	P	E	V	F	H	Y	F	K	Y	S	S	K	S	D	V	W	A	F	G	I	L	M	W	E	V	F	S	L	G	K	Q	P	Y	D	L	Y	D	N	S	E	V	V	V	K	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	T	A	H	A	G	A	K	F	P	I	K	W	T	A	P	E	S	L	A	Y	N	K	F	S	I	K	S	D	V	W	A	F	G	V	L	L	W	E	I	A	T	Y	G	M	S	P	Y	P	G	I	D	L	S	Q	V	Y	E	L	L
Template Known Secondary structure						T	T					G	G	G																													T	T	S			S	S	T	T			T	T	T
Template Predicted Secondary structure
Template SS confidence
		412	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.
		602	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	Q	G	H	R	L	Y	R	P	Q	L	A	S	D	T	I	Y	Q	I	M	Y	S	C	W	H	E	L	P	E	K	R	P	T	F	Q	Q	L	L	S	A	I	E	P	L	R	E	Q	D
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	K	D	Y	R	M	E	R	P	E	G	C	P	E	K	V	Y	E	L	M	R	A	C	W	Q	W	N	P	S	D	R	P	S	F	A	E	I	H	Q	A	F	E	T	M	F	Q	E	S
Template Known Secondary structure			T	T							T	T													T		S	S	G	G	G	S												T	S		S	S	S
Template Predicted Secondary structure
Template SS confidence
		472	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.