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Job DescriptionP25911
Confidence100.00%DateWed Jul 10 14:04:52 BST 2013
Rank210Aligned Residues256
% Identity23%Templatec3zonA_
PDB info PDB header:transferaseChain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: human tyk2 pseudokinase domain bound to a kinase inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   236...240.........250.........260.........270.........280.... .....290....
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Query Sequence  DKDAWEIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSV. QAFLEEANLM
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Template Sequence  QLSFHRVDQKEITQLSHLGQGTRTNVYEGRLRVELRVVLKVLDPSHHDIALAFYETASLM
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GGGTT



S

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   578.580.........590.........600.........610.........620.........630.......
 
   295....300.........310.........320.........330.........340.........350....
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Query Sequence  KTLQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEG
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Template Sequence  SQVSHTHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLR. RERGHVPMAWKMVVAQQLASA
Template Known Secondary structure  TT


TTB

TT

TT
B.TTT


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   663......670.........680.........690.........700 .........710.........720.
 
   355....360.........370.........380.........390.........400.... .....410..
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Query Sequence  MAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAK. . FPIKWTAP
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Template Sequence  LSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLAP
Template Known Secondary structure  TT





SGGG


STT






S
GGGS
TTTTS
G
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   722.......730.........740.........750.........760.........770.........780.
 
   413......420.........430.........440.........450.........460.........470..
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Query Sequence  EAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMSALSQGYRMPRMENCPDEL
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Template Sequence  ECL. . . PLSTAMDKWGFGATLLEICFDGEAPLQSRSPSEKEHFYQRQHRLPEPQ. . . . . L
Template Known Secondary structure  GG
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TTTTT

TTTTS
TT






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   782.. .....790.........800.........810.........820.........830.. .
 
   473......480.........490.........500
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Query Sequence  YDIMKMCWKEKAEERPTFDYLQSVLDDF
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Template Sequence  ATLTSQCLTYEPTQRPSFRTILRDLTRL
Template Known Secondary structure  T
SSGGGS

TT
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   842.......850.........860.........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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