Job Description P25911 Confidence 100.00% Date Wed Jul 10 14:04:52 BST 2013 Rank 77 Aligned Residues 240 % Identity 27% Template c3vw6B_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor Resolution 2.40 Å

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		239	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.		.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.
Predicted Secondary structure																																.
Query SS confidence																																.
Query Sequence		A	W	E	I	P	R	E	S	I	K	L	V	K	K	L	G	A	G	Q	F	G	E	V	W	M	G	Y	Y	N	N	.	S	T	K	V	A	V	K	T	L	K	P	G	T	M	S	V	Q	A	F	L	E	E	A	N	L	M	K	T	L
Query Conservation																																.
Alig confidence																																.												.	.	.	.	.
Template Conservation																																												.	.	.	.	.
Template Sequence		E	Y	D	Y	E	Y	D	E	N	G	D	R	V	V	L	G	K	G	T	Y	G	I	V	Y	A	G	R	D	L	S	N	Q	V	R	I	A	I	K	E	I	P	E	.	.	.	.	.	Q	P	L	H	E	E	I	A	L	H	K	H	L
Template Known Secondary structure							B		T	T	S	S	B							S	S	S								T	T	T												.	.	.	.	.											T	T
Template Predicted Secondary structure																																												.	.	.	.	.
Template SS confidence
		672	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.						.	.	.	.	.	.	720	.	.	.	.	.	.
		298	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.		.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.
Predicted Secondary structure																																										.
Query SS confidence																																										.
Query Sequence		Q	H	D	K	L	V	R	L	Y	A	V	V	T	K	E	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	G	.	K	V	L	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A
Query Conservation																																										.
Alig confidence																																										.
Template Conservation
Template Sequence		K	H	K	N	I	V	Q	Y	L	G	S	F	S	E	N	G	F	I	K	I	F	M	E	Q	V	P	G	G	S	L	S	A	L	L	R	S	K	W	G	P	L	K	D	N	E	Q	T	I	G	F	Y	T	K	Q	I	L	E	G	L	K
Template Known Secondary structure				T	T	B										T	T										T	T		B								T	T				T	T
Template Predicted Secondary structure
Template SS confidence
		733	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.
		357	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.		.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.
Predicted Secondary structure																					.
Query SS confidence																					.
Query Sequence		Y	I	E	R	K	N	Y	I	H	R	D	L	R	A	A	N	V	L	V	.	S	E	S	L	M	C	K	I	A	D	F	G	L	A	R	V	I	E	D	N	E	Y	T	A	R	E	G	A	K	F	P	I	K	W	T	A	P	E	A	I
Query Conservation																					.
Alig confidence																					.																			.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																								.	.	.	.	.	.	.	.	.	.	.
Template Sequence		Y	L	H	D	N	Q	I	V	H	R	D	I	K	G	D	N	V	L	I	N	T	Y	S	G	V	L	K	I	S	D	F	G	T	S	K	R	L	T	.	.	.	.	.	.	.	.	.	.	.	G	T	L	Q	Y	M	A	P	E	I	I
Template Known Secondary structure						T	T				S			S	G	G	G					T	T	T									S	S						.	.	.	.	.	.	.	.	.	.	.			G	G	G
Template Predicted Secondary structure																																								.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		793	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830												.	.	.	.	.	.	.	.	.	840	.
		416	.	.	.			420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.			.	.	460	.	.	.	.	.	.	.	.	.	470	.
Predicted Secondary structure						.	.																																							.	.
Query SS confidence						.	.																																							.	.
Query Sequence		N	F	G	C	.	.	F	T	I	K	S	D	V	W	S	F	G	I	L	L	Y	E	I	V	T	Y	G	K	I	P	Y	P	G	R	T	N	A	D	V	M	S	A	L	S	.	.	Q	G	Y	R	M	P	R	M	E	N	C	P	D	E
Query Conservation						.	.																																							.	.
Alig confidence						.	.																				.																			.	.
Template Conservation																											.
Template Sequence		D	K	G	P	R	G	Y	G	K	A	A	D	I	W	S	L	G	C	T	I	I	E	M	A	T	.	G	K	P	P	F	Y	E	L	G	E	P	Q	A	A	M	F	K	V	G	M	F	K	V	H	P	E	I	P	E	S	M	S	A	E
Template Known Secondary structure					G	G	G		S																		.	S	S		T	T	G	G	G		S												T							T	T	S
Template Predicted Secondary structure																											.
Template SS confidence
		852	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.		.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
		472	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	Y	D	I	M	K	M	C	W	K	E	K	A	E	E	R	P	T	F	D	Y	L	Q	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	K	A	F	I	L	K	C	F	E	P	D	P	D	K	R	A	C	A	N	D	L	L	V
Template Known Secondary structure										T		S		T	T	T	S								T
Template Predicted Secondary structure
Template SS confidence
		911	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D