Job Description P25911 Confidence 100.00% Date Wed Jul 10 14:04:52 BST 2013 Rank 309 Aligned Residues 240 % Identity 25% Template c3ttjA_ PDB info PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:mitogen-activated protein kinase 10; PDBTitle: crystal structure of jnk3 complexed with cc-359, a jnk inhibitor for2 the prevention of ischemia-reperfusion injury Resolution 2.10 Å

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		238	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.		.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.				.	.	.	290	.	.	.
Predicted Secondary structure																																	.																			.	.	.
Query SS confidence																																	.																			.	.	.
Query Sequence		D	A	W	E	I	P	R	E	S	I	K	L	V	K	K	L	G	A	G	Q	F	G	E	V	W	M	G	Y	Y	N	N	.	S	T	K	V	A	V	K	T	L	K	P	G	T	M	S	V	Q	A	.	.	.	F	L	E	E	A	N	L
Query Conservation																																	.																			.	.	.
Alig confidence								.																									.																			.	.	.
Template Conservation								.
Template Sequence		S	T	F	T	V	L	.	K	R	Y	Q	N	L	K	P	I	G	S	G	A	Q	G	I	V	C	A	A	Y	D	A	V	L	D	R	N	V	A	I	K	K	L	S	R	P	F	Q	N	Q	T	H	A	K	R	A	Y	R	E	L	V	L
Template Known Secondary structure								.	T	T											S	S									T	T	T	T										S	G	G	G	S
Template Predicted Secondary structure								.
Template SS confidence
		56	.	.	.	60	.		.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.
		294	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.							.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.
Predicted Secondary structure																				.	.	.	.	.	.
Query SS confidence																				.	.	.	.	.	.
Query Sequence		M	K	T	L	Q	H	D	K	L	V	R	L	Y	A	V	V	T	K	.	.	.	.	.	.	E	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	G	K	V	L	L	P	K	L	I	D	F
Query Conservation																				.	.	.	.	.	.
Alig confidence																				.	.	.	.	.	.																						.	.	.	.	.
Template Conservation																																															.	.	.	.	.
Template Sequence		M	K	C	V	N	H	K	N	I	I	S	L	L	N	V	F	T	P	Q	K	T	L	E	E	F	Q	D	V	Y	L	V	M	E	L	M	D	A	N	L	C	Q	V	I	Q	M	.	.	.	.	.	E	L	D	H	E	R	M	S	Y	L
Template Known Secondary structure								T	T	B				S					S			S	T	T	T												S								T	S	.	.	.	.	.
Template Predicted Secondary structure																																															.	.	.	.	.
Template SS confidence
		115	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.						160	.	.	.	.	.	.	.	.	.
		348	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	A	Q	I	A	E	G	M	A	Y	I	E	R	K	N	Y	I	H	R	D	L	R	A	A	N	V	L	V	S	E	S	L	M	C	K	I	A	D	F	G	L	A	R	V	I	E	D	N	E	Y	T	A	R	E	G	A	K	F	P	I
Query Conservation
Alig confidence																																																			.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																			.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	Y	Q	M	L	C	G	I	K	H	L	H	S	A	G	I	I	H	R	D	L	K	P	S	N	I	V	V	K	S	D	C	T	L	K	I	L	D	F	G	L	A	S	F	M	M	V	T	R	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure															T	T								G	G	G					T	T	S																		.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																			.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.
		408	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.
Predicted Secondary structure																																																				.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																				.	.	.	.	.	.	.	.	.	.
Query Sequence		K	W	T	A	P	E	A	I	N	F	G	C	F	T	I	K	S	D	V	W	S	F	G	I	L	L	Y	E	I	V	T	Y	G	K	I	P	Y	P	G	R	T	N	A	D	V	M	S	A	L	S	.	.	.	.	.	.	.	.	.	.
Query Conservation																																																				.	.	.	.	.	.	.	.	.	.
Alig confidence																																	.																			.	.	.	.	.	.	.	.	.	.
Template Conservation																																	.
Template Sequence		Y	Y	R	A	P	E	V	I	L	G	M	G	Y	K	E	N	V	D	I	W	S	V	G	C	I	M	G	E	M	V	R	.	H	K	I	L	F	P	G	R	D	Y	I	D	Q	W	N	K	V	I	E	Q	L	G	T	P	C	P	E	F
Template Known Secondary structure		T	T							T	T					T	T																.	S	S		S	S			S	S														S
Template Predicted Secondary structure																																	.
Template SS confidence
		228	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.		.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.
																																	458	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Q	G	Y	R	M	P	R	M	E	N	C	P	D	E	L	Y	D	I	M	K	M	C	W	K	E	K	A	E	E
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		M	K	K	L	Q	P	T	V	R	N	Y	V	E	N	R	P	K	Y	A	G	L	T	F	P	K	L	F	P	D	S	L	F	P	A	D	S	E	H	N	K	L	K	A	S	Q	A	R	D	L	L	S	K	M	L	V	I	D	P	A	K
Template Known Secondary structure			T	T	S									T	T	S												S		G	G	G	S			S	S																		S		S	S	T	T	T
Template Predicted Secondary structure
Template SS confidence
		287	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.
		487	.	.	490	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	P	T	F	D	Y	L	Q	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	I	S	V	D	D	A	L	Q
Template Known Secondary structure		S								T
Template Predicted Secondary structure
Template SS confidence
		347	.	.	350	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D