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Job DescriptionP25911
Confidence100.00%DateWed Jul 10 14:04:52 BST 2013
Rank193Aligned Residues251
% Identity25%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   245....250.........260.........270.........280.........290.........300....
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Query Sequence  ESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVR
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Template Sequence  RDITLLECVGKGRYGEVWRGSW. QGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILG
Template Known Secondary structure  TTTT.TT
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   206...210.........220....... ..230.........240.........250.........260....
 
   305... .310.........320.........330.........340.........350.........360
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Query Sequence  LYAV. . . . VTKEEPIYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIER
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Template Sequence  FIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLT. . . TLDTVSCLRIVLSIASGLAHLHI
Template Known Secondary structure  TT

TT
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   265....270.........280.........290........ .300.........310.........320.
 
   361.. ......370.........380.........390... ......400.........
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Query Sequence  KNY. . . . . . . . IHRDLRAANVLVSESLMCKIADFGLARVIE. . . DNEYTAREGAKFPIKW
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Template Sequence  EIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRY
Template Known Secondary structure 
B
STT
B

S

SGGG
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TT
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   322.......330.........340.........350.........360.........370.........380.
 
   410......... 420.........430.........440.........
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Query Sequence  TAPEAINFGC. . . . . . FTIKSDVWSFGILLYEIVTYGKIPYPGRTN. . . . . . . . . . . . . .
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Template Sequence  MAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPNDPS
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TT


TT
T.TB
BTTB





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   382.......390.........400.........410...... ...420.........430.........440
 
   450.........460....... ..470.........480.........490.........500
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Query Sequence  . ADVMSALSQGYRMPRMEN. . . . . . CPDELYDIMKMCWKEKAEERPTFDYLQSVLDDF
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Template Sequence  FEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
Template Known Secondary structure  TTS






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   441........450.........460.........470.........480.........490........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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