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Job DescriptionP25911
Confidence100.00%DateWed Jul 10 14:04:52 BST 2013
Rank78Aligned Residues250
% Identity36%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   238.240.........250.........260.........270.........280...... ...290....
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Query Sequence  DAWEIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQA. . . FLEEANLM
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Template Sequence  DDWEIPDGQITVGQRIGSGSFGTVYKGKWHG. . DVAVKMLNVTAPTPQQLQAFKNEVGVL
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B

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   448.450.........460.........470........ .480.........490.........500.....
 
   295....300.........310.........320.........330.........340.........350....
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Query Sequence  KTLQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEG
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Template Sequence  RKTRHVNILLFMGYSTKPQL. AIVTQWCEGSSLYHHLH. IIETKFEMIKLIDIARQTAQG
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   506...510.........520..... ....530.........540.. .......550.........560...
 
   355....360.........370.........380.........390.........400.........410....
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Query Sequence  MAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEA
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Template Sequence  MDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVL. . . . . . . . . . . SGSILWMAPEV
Template Known Secondary structure  TT
B
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SGGGTTT


TT
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TT

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   564.....570.........580.........590.........600. ........610..
 
   415.... 420.........430.........440.........450. ........460... ...
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Query Sequence  INFGC. . . FTIKSDVWSFGILLYEIVTYGKIPYPGRTNAD. VMSALSQGYRMP. . . . RME
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Template Sequence  IRMQDKNPYSFQSDVYAFGIVLYELMT. GQLPYSNINNRDQIIFMVGRGYLSPDLSKVRS
Template Known Secondary structure  TT
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S.SS
TTTT


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   625....630.........640.........650. ........660.........670.........680...
 
   467..470.........480.........490.........500...
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Query Sequence  NCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTA
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Template Sequence  NCPKAMKRLMAECLKKKRDERPLFPQILASIELLARS
Template Known Secondary structure  TS
T
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T
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   684.....690.........700.........710.........720
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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