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Job DescriptionP25911
Confidence100.00%DateWed Jul 10 14:04:52 BST 2013
Rank180Aligned Residues272
% Identity33%Templatec2yhvA_
PDB info PDB header:transferaseChain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of l1196m mutant anaplastic lymphoma kinase
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   224.....230.........240.........250.........260.........270........ .280.
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Query Sequence  KACISPKPQKPWDKDAWEIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLK. . PGT
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Template Sequence  NPNYCFAGKTSSISDLKEVPRKNITL. . . IRGLAFGEVYEGQV. . PLQVAVKTLPEVCSE
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   1093......1100.........1110........ .1120.........1130.. .......1140.......
 
   282.......290.........300.........310.........320.........330.... ..
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Query Sequence  MSVQAFLEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLDFLKSD. . . . . EG
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Template Sequence  QDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILMELMAGGDLKSFLRETRPRPSQP
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   11591160.........1170.........1180.........1190.........1200.........1210........
 
   337..340.........350.........360.........370.........380.........390......
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Query Sequence  GKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNE
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Template Sequence  SSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDF. . GMARD
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   12191220.........1230.........1240.........1250.........1260.........1270. .....
 
   397..400.........410.........420.........430.........440.........450......
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Query Sequence  YTAREGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMSAL
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Template Sequence  IYRGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFV
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   1277..1280.........1290.........1300.........1310.........1320.........1330......
 
   457..460.........470.........480.........490.........500..
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Query Sequence  SQGYRMPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYT
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Template Sequence  TSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQ
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   1343......1350.........1360.........1370.........1380........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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