Job Description P25911 Confidence 100.00% Date Wed Jul 10 14:04:52 BST 2013 Rank 7 Aligned Residues 370 % Identity 35% Template c2ozoA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70 Resolution 2.60 Å Model Dimensions (Å) X:95.178 Y:53.690 Z:44.966

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		121	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Predicted Secondary structure
Query SS confidence
Query Sequence		V	N	T	L	E	T	E	E	W	F	F	K	D	I	T	R	K	D	A	E	R	Q	L	L	A	P	G	N	S	A	G	A	F	L	I	R	E	S	E	T	L	K	G	S	F	S	L	S	V	R	D	Y	D	P	M	H	G	D	V	I
Query Conservation
Alig confidence																																																				.	.	.	.	.
Template Conservation																																																				.	.	.	.	.
Template Sequence		P	D	P	A	A	H	L	P	F	F	Y	G	S	I	S	R	A	E	A	E	E	H	L	K	L	A	G	M	A	D	G	L	F	L	L	R	Q	C	L	R	S	L	G	G	Y	V	L	S	L	V	.	.	.	.	.	H	D	V	R	F
Template Known Secondary structure				T	T	S	S		T	T	B		B	S												T	T	T			T	T								T	T	B	T	T								.	.	.	.	.		T	T
Template Predicted Secondary structure																																																				.	.	.	.	.
Template SS confidence
		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.						.	.	.	.	.
		181	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.
Predicted Secondary structure																																																								.	.	.	.	.	.
Query SS confidence																																																								.	.	.	.	.	.
Query Sequence		K	H	Y	K	I	R	S	L	D	N	G	G	Y	Y	I	S	P	R	I	T	F	P	C	I	S	D	M	I	K	H	Y	Q	K	Q	S	D	G	L	C	R	R	L	E	K	A	C	I	S	P	K	P	Q	K	P	.	.	.	.	.	.
Query Conservation																																																								.	.	.	.	.	.
Alig confidence																																																								.	.	.	.	.	.
Template Conservation
Template Sequence		H	H	F	P	I	E	R	Q	L	N	G	T	Y	A	I	A	G	G	K	A	H	C	G	P	A	E	L	C	E	F	Y	S	R	D	P	D	G	L	P	C	N	L	R	K	P	C	N	R	P	S	G	L	E	P	Q	P	G	V	F	D
Template Known Secondary structure										T	T	S					T	T	S			B	S	S									T	S			T	T	S	S	S				S	B					T	T				B
Template Predicted Secondary structure
Template SS confidence
		57	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		C	L	R	D	A	M	V	R	D	Y	V	R	Q	T	W	K	L	E	G	E	A	L	E	Q	A	I	I	S	Q	A	P	Q	V	E	K	L	I	A	T	T	A	H	E	R	M	P	W	Y	H	S	S	L	T	R	E	E	A	E	R	K
Template Known Secondary structure																																							T	T	S		T	T	T	S	T	T	B		T	T
Template Predicted Secondary structure
Template SS confidence
		117	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		L	Y	S	G	A	Q	T	D	G	K	F	L	L	R	P	R	K	E	Q	G	T	Y	A	L	S	L	I	Y	G	K	T	V	Y	H	Y	L	I	S	Q	D	K	A	G	K	Y	C	I	P	E	G	T	K	F	D	T	L	W	Q	L	V
Template Known Secondary structure			S	S	S				T	T								S	S	T	T									T	T											T	T						T	T	S				S	S
Template Predicted Secondary structure
Template SS confidence
		177	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
																																						235	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	W	D	K	D	A	W	E	I	P	R	E	S	I	K	L	V	K	K	L	G	A	G	Q	F
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		E	Y	L	K	L	K	A	D	G	L	I	Y	C	L	K	E	A	C	P	N	M	D	T	S	V	F	E	S	P	F	S	D	P	E	E	L	K	D	K	K	L	F	L	K	R	D	N	L	L	I	A	D	I	E	L	G	C	G	N	F
Template Known Secondary structure									T	T		S	S				S	B								S		S	S	S	S	S		S		S	S					S	B			T	T	S												S	S
Template Predicted Secondary structure
Template SS confidence
		237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.
		259	260	.	.	.	.	.	.	.	.	.	270				.	.	.	.	.	.	.	.	.			280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.
Predicted Secondary structure														.	.	.										.	.
Query SS confidence														.	.	.										.	.
Query Sequence		G	E	V	W	M	G	Y	Y	N	N	S	T	.	.	.	K	V	A	V	K	T	L	K	P	.	.	G	T	M	S	V	Q	A	F	L	E	E	A	N	L	M	K	T	L	Q	H	D	K	L	V	R	L	Y	A	V	V	T	K	E	E
Query Conservation														.	.	.										.	.
Alig confidence														.	.	.										.	.																															.
Template Conservation																																																										.
Template Sequence		G	S	V	R	Q	G	V	Y	R	M	R	K	K	Q	I	D	V	A	I	K	V	L	K	Q	G	T	E	K	A	D	T	E	E	M	M	R	E	A	Q	I	M	H	Q	L	D	N	P	Y	I	V	R	L	I	G	V	C	.	Q	A	E
Template Known Secondary structure		S										S	S															S	S	T	T												T	T				T	T	B								.		S	S
Template Predicted Secondary structure																																																										.
Template SS confidence
		350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.		.	.	.
		314	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	G	K	V	L	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	Y	I	E	R	K	N	Y	I	H	R	D	L	R	A	A	N	V
Query Conservation
Alig confidence																					.
Template Conservation																					.
Template Sequence		A	L	M	L	V	M	E	M	A	G	G	G	P	L	H	K	F	L	V	.	G	K	R	E	E	I	P	V	S	N	V	A	E	L	L	H	Q	V	S	M	G	M	K	Y	L	E	E	K	N	F	V	H	R	N	L	A	A	R	N	V
Template Known Secondary structure		S									T	T		B						T	.	T		T	T	T	S																						T	T				S			S	G	G	G
Template Predicted Secondary structure																					.
Template SS confidence
		409	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.		.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.
		374	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	V	S	E	S	L	M	C	K	I	A	D	F	G	L	A	R	V	I	E	D	N	E	Y	T	A	R	E	G	A	K	F	P	I	K	W	T	A	P	E	A	I	N	F	G	C	F	T	I	K	S	D	V	W	S	F	G	I	L	L
Query Conservation
Alig confidence																					.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																					.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	L	V	N	R	H	Y	A	K	I	S	D	F	G	L	S	K	A	L	.	.	.	.	.	.	.	.	.	.	.	.	G	P	L	K	W	Y	A	P	E	C	I	N	F	R	K	F	S	S	R	S	D	V	W	S	Y	G	V	T	M
Template Known Secondary structure						T	T								S	T	T	T	T		.	.	.	.	.	.	.	.	.	.	.	.				T	T	S
Template Predicted Secondary structure																					.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		468	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.													.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.
		434	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	E	I	V	T	Y	G	K	I	P	Y	P	G	R	T	N	A	D	V	M	S	A	L	S	Q	G	Y	R	M	P	R	M	E	N	C	P	D	E	L	Y	D	I	M	K	M	C	W	K	E	K	A	E	E	R	P	T	F	D	Y	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		W	E	A	L	S	Y	G	Q	K	P	Y	K	K	M	K	G	P	E	V	M	A	F	I	E	Q	G	K	R	M	E	C	P	P	E	C	P	P	E	L	Y	A	L	M	S	D	C	W	I	Y	K	W	E	D	R	P	D	F	L	T	V
Template Known Secondary structure						T	T	S			T	T	T	T			S									T	T							T	T												T	T		S	S	T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.
		494	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	S	V	L	D	D	F	Y	T	A	T	E	G	Q	Y	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	Q	R	M	R	A	C	Y	Y	S	L	A	S	K	V	E
Template Known Secondary structure													S		S
Template Predicted Secondary structure
Template SS confidence
		590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.