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Job DescriptionP25911
Confidence100.00%DateWed Jul 10 14:04:52 BST 2013
Rank18Aligned Residues267
% Identity39%Templatec2ivsA_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
Resolution2.00 Å
Model Dimensions (Å)X:46.983 Y:60.432 Z:40.428

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   236...240.........250.........260....... ..270.........280..... ..
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Query Sequence  DKDAWEIPRESIKLVKKLGAGQFGEVWMGYYN. . . . . . NSTKVAVKTLKPGTMSVQ. . AF
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Template Sequence  EDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDL
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TTTB

GGG
SSSTGGG
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TT

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   713......720.........730.........740.........750.........760.........770..
 
   288.290.........300.........310.........320.........330...... ...340.
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Query Sequence  LEEANLMKTLQHDKLVRLYAVVTKEEPIYIITEFMAKGSLLDFLKSDEG. . . . . . GKVLL
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Template Sequence  LSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLRALTM
Template Known Secondary structure  TT


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TT
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   773......780.........790.........800.........810.........820.........830..
 
   342.......350.........360.........370.........380.........390. ........400
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Query Sequence  PKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARV. IEDNEYTAR
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Template Sequence  GDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKR
Template Known Secondary structure  TT



SGGGTTT


TT

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S
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   849850.........860.........870.........880.........890.........900........
 
   401........410.........420.........430.........440.........450.........460
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Query Sequence  EGAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMSALSQGY
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Template Sequence  SQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGH
Template Known Secondary structure  S


S
GGG



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   909910.........920.........930.........940.........950.........960........
 
   461........470.........480.........490.........500..
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Query Sequence  RMPRMENCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYT
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Template Sequence  RMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMV
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TT

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   969970.........980.........990.........1000.........1010
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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