Job Description P25911 Confidence 100.00% Date Wed Jul 10 14:04:52 BST 2013 Rank 5 Aligned Residues 430 % Identity 76% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å Model Dimensions (Å) X:66.645 Y:79.228 Z:51.594

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		67	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	V	V	A	L	Y	P	Y	D	G	I	H	P	D	D	L	S	F	K	K	G	E	K	M	K	V	L	E	E	H	G	E	W	W	K	A	K	S	L	S	S	K	R	E	G	F	I	P	S	N	Y	V	A	K	V	N	T	L	E	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		I	V	V	A	L	Y	D	Y	E	A	I	H	H	E	D	L	S	F	Q	K	G	D	Q	M	V	V	L	E	E	S	G	E	W	W	K	A	R	S	L	A	T	R	K	E	G	Y	I	P	S	N	Y	V	A	R	V	D	S	L	E	T
Template Known Secondary structure						S	S		B				S	S	S	B			B		T	T										T	T							T	T	T								G	G	G				T	T	S	G	G	G
Template Predicted Secondary structure
Template SS confidence
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
		127	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	E	W	F	F	K	D	I	T	R	K	D	A	E	R	Q	L	L	A	P	G	N	S	A	G	A	F	L	I	R	E	S	E	T	L	K	G	S	F	S	L	S	V	R	D	Y	D	P	M	H	G	D	V	I	K	H	Y	K	I	R
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	E	W	F	F	K	G	I	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	Y	S	L	S	V	R	D	Y	D	P	R	Q	G	D	T	V	K	H	Y	K	I	R
Template Known Secondary structure		S	T	T			T	T											T	S	T	T			T	T								S	S	S	T	T											T	T	T										B
Template Predicted Secondary structure
Template SS confidence
		121	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
		187	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	L	D	N	G	G	Y	Y	I	S	P	R	I	T	F	P	C	I	S	D	M	I	K	H	Y	Q	K	Q	S	D	G	L	C	R	R	L	E	K	A	C	I	S	P	K	P	Q	K	P	W	D	K	D	A	W	E	I	P	R	E	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		T	L	D	N	G	G	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L	C	Q	K	L	S	V	P	C	M	S	S	K	P	Q	K	P	W	E	K	D	A	W	E	I	P	R	E	S
Template Known Secondary structure				S	T	T				S	S	T	T	S			S	S								T	T	S	S		S	S		S	S				S	B												T	T		S	B			G	G	G
Template Predicted Secondary structure
Template SS confidence
		181	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
		247	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	K	L	V	K	K	L	G	A	G	Q	F	G	E	V	W	M	G	Y	Y	N	N	S	T	K	V	A	V	K	T	L	K	P	G	T	M	S	V	Q	A	F	L	E	E	A	N	L	M	K	T	L	Q	H	D	K	L	V	R	L	Y
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	K	H	T	K	V	A	V	K	T	M	K	P	G	S	M	S	V	E	A	F	L	A	E	A	N	V	M	K	T	L	Q	H	D	K	L	V	K	L	H
Template Known Secondary structure												T	T									T	T	T												S	S														T				T	T	B
Template Predicted Secondary structure
Template SS confidence
		241	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
		307	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	V	V	T	K	E	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	G	K	V	L	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	Y	I	E	R	K	N	Y	I	H	R
Query Conservation
Alig confidence							.
Template Conservation							.
Template Sequence		A	V	V	T	K	.	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A	F	I	E	Q	R	N	Y	I	H	R
Template Known Secondary structure						S	.	S	S									T	T		B							S	T	T	G	G	G																							T	T				S
Template Predicted Secondary structure							.
Template SS confidence
		301	.	.	.	.		.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.
		367	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	L	R	A	A	N	V	L	V	S	E	S	L	M	C	K	I	A	D	F	G	L	A	R	V	I	E	D	N	E	Y	T	A	R	E	G	A	K	F	P	I	K	W	T	A	P	E	A	I	N	F	G	C	F	T	I	K	S	D	V
Query Conservation
Alig confidence																										.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																										.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		D	L	R	A	A	N	I	L	V	S	A	S	L	V	C	K	I	A	D	F	G	L	A	R	.	.	.	.	.	.	.	.	.	.	.	.	.	V	I	P	I	K	W	T	A	P	E	A	I	N	F	G	S	F	T	I	K	S	D	V
Template Known Secondary structure				S	G	G	G					T	T								T	T	G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	T			G	G	G	S
Template Predicted Secondary structure																										.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.														.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.
		427	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		W	S	F	G	I	L	L	Y	E	I	V	T	Y	G	K	I	P	Y	P	G	R	T	N	A	D	V	M	S	A	L	S	Q	G	Y	R	M	P	R	M	E	N	C	P	D	E	L	Y	D	I	M	K	M	C	W	K	E	K	A	E	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P	E	V	I	R	A	L	E	R	G	Y	R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	M	M	R	C	W	K	N	R	P	E	E
Template Known Secondary structure													T	T	T			S	S	T	T												T	T							T	T													T		S	S	G	G	G
Template Predicted Secondary structure
Template SS confidence
		420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.
		487	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510
Predicted Secondary structure
Query SS confidence
Query Sequence		R	P	T	F	D	Y	L	Q	S	V	L	D	D	F	Y	T	A	T	E	G	Q	Y	Q	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		R	P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A	T	E	S	Q	E	E	I
Template Known Secondary structure		S												T	T	T	S		G	G	G
Template Predicted Secondary structure
Template SS confidence
		480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.