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Job DescriptionP25911
Confidence100.00%DateWed Jul 10 14:04:52 BST 2013
Rank1Aligned Residues444
% Identity59%Templatec1y57A_
PDB info PDB header:transferaseChain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
Resolution1.91 Å
Model Dimensions (Å)X:91.904 Y:79.252 Z:49.836

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   66...70.........80.........90..... ....100.........110.........120....
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Query Sequence  DIVVALYPYDGIHPDDLSFKKGEKMKVLEE. HGEWWKAKSLSSKREGFIPSNYVAKVNTL
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Template Sequence  TTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSI
Template Known Secondary structure  TSS
B


SSSB

B
TT

S

SSSSTTT

GGGTTSG
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   84.....90.........100.........110.........120.........130.........140...
 
   125....130.........140.........150.........160.........170.........180....
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Query Sequence  ETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDPMHGDVIKHYK
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Template Sequence  QAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYK
Template Known Secondary structure  GGSTTS

T
TT

TT

SSSTT
TTT
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   144.....150.........160.........170.........180.........190.........200...
 
   185....190.........200.........210.........220......... 230.........240...
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Query Sequence  IRSLDNGGYYISPRITFPCISDMIKHYQKQSDGLCRRLEKACISP. KPQKPWDKDAWEIP
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Template Sequence  IRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIP
Template Known Secondary structure 
SSS
SSTTSSS

TTSSS



B







SS



TTB

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   204.....210.........220.........230.........240.........250.........260...
 
   244.....250.........260.........270.........280.........290.........300...
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Query Sequence  RESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHDKLV
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Template Sequence  RESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLV
Template Known Secondary structure  GGGTTTTT
TTSS



TTB
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   264.....270.........280.........290.........300.........310.........320...
 
   304.....310.........320.........330.........340.........350.........360...
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Query Sequence  RLYAVVTKEEPIYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNY
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Template Sequence  QLYAVVS. EEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNY
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.SSS


TTS

TT
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   324.....330 .........340.........350.........360.........370.........380..
 
   364.....370.........380.........390.........400.........410.........420...
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Query Sequence  IHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCFTIK
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Template Sequence  VHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIK
Template Known Secondary structure 
S

SGGG
GGG



TT


SS




TTTT
SGGGS




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   383......390.........400.........410.........420.........430.........440..
 
   424.....430.........440.........450.........460.........470.........480...
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Query Sequence  SDVWSFGILLYEIVTYGKIPYPGRTNADVMSALSQGYRMPRMENCPDELYDIMKMCWKEK
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Template Sequence  SDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKE
Template Known Secondary structure  TTS

SSTT

TT





TT

T
SS
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   443......450.........460.........470.........480.........490.........500..
 
   484.....490.........500.........510
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Query Sequence  AEERPTFDYLQSVLDDFYTATEGQYQQ
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Template Sequence  PEERPTFEYLQAFLEDYFTSTEPQYQP
Template Known Secondary structure  GGGS

TT
TT


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   503......510.........520.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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