|   |   |
266 | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
I | D | P | S | E | L | A | F | V | K | E | I | G | S | G | Q | F | G | V | V | H | L | G | E | W | R | A | H | I | P | V | A | I | K | A | I | N | E | G | S | M | S | E | E | D | F | I | E | E | A | K | V | M | M | K | L | S | H | S | R |
| Query Conservation |   |
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |
|
|
|
| Template Sequence |   |
I | D | P | S | E | L | T | F | V | Q | E | I | G | S | G | Q | F | G | L | V | H | L | G | Y | W | L | N | K | D | K | V | A | I | K | T | I | R | E | G | A | M | S | E | E | D | F | I | E | E | A | E | V | M | M | K | L | S | H | P | K |
| Template Known Secondary structure |   |
B |
|
| S |
|  |  |  |  |  |  |  |  |
|
| S | S |
|
|  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |
|
| S | S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
358 | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . |
|   |
|   |   |
326 | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
L | V | Q | L | Y | G | V | C | I | Q | Q | K | P | L | Y | I | V | T | E | F | M | E | N | G | C | L | L | D | Y | L | R | E | R | K | G | Q | L | Q | K | A | L | L | L | S | M | C | Q | D | I | C | E | G | M | A | Y | L | E | R | S | C |
| Query Conservation |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
L | V | Q | L | Y | G | V | C | L | E | Q | A | P | I | C | L | V | F | E | F | M | E | H | G | C | L | S | D | Y | L | R | T | Q | R | G | L | F | A | A | E | T | L | L | G | M | C | L | D | V | C | E | G | M | A | Y | L | E | E | A | C |
| Template Known Secondary structure |   |
B |
|
|  |  |  |  |  |
| S | S | S | S |
|  |  |  |  |  |
|
| T | T |
| B |  |  |  |  |  |  | T | T | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
418 | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . |
|   |
|   |   |
386 | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
Y | I | H | R | D | L | A | A | R | N | C | L | V | S | S | A | C | V | V | K | I | S | D | F | G | M | A | R | Y | V | L | D | D | E | Y | I | S | S | S | G | A | K | F | P | V | K | W | C | P | P | E | V | F | H | F | N | K | Y | S | S |
| Query Conservation |   |
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |
|   |   |   |   |   |
|   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
| Template Sequence |   |
V | I | H | R | D | L | A | A | R | N | C | L | V | G | E | N | Q | V | I | K | V | S | D | F | G | P | V | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
W | A | S | P | E | V | F | S | F | S | R | Y | S | S |
| Template Known Secondary structure |   |
|
|
| T | T |
| S | G | G | G |  |  |  |
| G | G | G |
|  |  |  |
| S |
|
|
| T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S |
|
|  |  |  |  | T | T |
|
|
|
|  |
| Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
478 | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 510 | . | . | . | . | . | . | . | . | . |
|   |
|   |   |
446 | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . |
| Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
K | S | D | V | W | S | F | G | V | L | M | W | E | V | F | T | E | G | K | M | P | F | E | N | K | S | N | L | Q | V | V | E | A | I | S | Q | G | F | R | L | Y | R | P | H | L | A | P | M | T | I | Y | R | V | M | Y | S | C | W | H | E |
| Query Conservation |   |
|
|
|
|
|
|   |
|
|
|
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
  |   |
|
|   |
|   |
|   |   |
|
|
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
| Template Sequence |   |
K | S | D | V | W | S | F | G | V | L | M | W | E | V | F | S | E | G | K | I | P | Y | E | N | R | S | N | S | E | V | V | E | D | I | S | T | G | F | R | L | Y | K | P | R | L | A | S | T | H | V | Y | Q | I | M | N | H | C | W | K | E |
| Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
| T | T |
| S |
|
|  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  | T |
| S |
| Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
538 | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . |
|   |
|   |   |
506 | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . |
| Predicted Secondary structure |   |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Query Sequence |   |
S | P | K | G | R | P | T | F | A | E | L | L | Q | V | L | T | E | I | A | E | T |
| Query Conservation |   |
|
|   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |
|   |
|
|
| Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Template Conservation |   |
|
|   |   |
|
|
|   |   |
|
|   |   |   |
|   |   |
|   |   |
|
| Template Sequence |   |
R | P | E | D | R | P | A | F | S | R | L | L | R | Q | L | A | E | I | A | E | S |
| Template Known Secondary structure |   |
S | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| Template Predicted Secondary structure |   |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
598 | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . |
|   |