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Job DescriptionP42682
Confidence100.00%DateTue Jul 30 13:16:14 BST 2013
Rank192Aligned Residues251
% Identity23%Templatec3mtfB_
PDB info PDB header:transferaseChain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   269270.........280.........290.........300.........310.........320........
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Query Sequence  SELAFVKEIGSGQFGVVHLGEWRAHIPVAIKAINEGSMSEEDFIEEAKVMMKLSHSRLVQ
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Template Sequence  RDITLLECVGKGRYGEVWRGSWQGE. NVAVKIFSSRDEKSWFRETELYNTVMLRHENILG
Template Known Secondary structure  TTTTTT.
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   206...210.........220.........230 .........240.........250.........260....
 
   329330.. .......340.........350.........360.........370.........380....
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Query Sequence  LYGV. . . . CIQQKPLYIVTEFMENGCLLDYLRERKGQLQKALLLSMCQDICEGMAYLERS
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Template Sequence  FIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTT. . LDTVSCLRIVLSIASGLAHLHIE
Template Known Secondary structure  TT

TT
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   265....270.........280.........290......... 300.........310.........320..
 
   385. ...390.........400.........410...... ...420.........430...
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Query Sequence  CY. . . . . . . . IHRDLAARNCLVSSACVVKISDFGMARYVL. . . DDEYISSSGAKFPVKWC
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Template Sequence  IFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYM
Template Known Secondary structure  B
STT
B

S

SGGG
TTS



TT
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   323......330.........340.........350.........360.........370.........380..
 
   434.....440.. .......450.........460.........470..
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Query Sequence  PPEVFHFNK. . . . . . YSSKSDVWSFGVLMWEVFTEGKMPFENKSN. . . . . . . . . . . . . . .
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Template Sequence  APEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR. RMVSNGIVEDYKPPFYDVVPNDPSF
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TT


TT
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BTTB





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   383......390.........400.........410...... ...420.........430.........440.
 
   473......480.........490 .........500.........510.........520...
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Query Sequence  LQVVEAISQGFRLYRPHL. . . . . . APMTIYRVMYSCWHESPKGRPTFAELLQVLTEI
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Template Sequence  EDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI
Template Known Secondary structure  TTS






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   442.......450.........460.........470.........480.........490........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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