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Job DescriptionP42682
Confidence100.00%DateTue Jul 30 13:16:14 BST 2013
Rank97Aligned Residues241
% Identity59%Templatec3k54A_
PDB info PDB header:transferaseChain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases.
Resolution1.94 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   261........270.........280.........290.........300.........310.........320
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Query Sequence  YEKWEIDPSELAFVKEIGSGQFGVVHLGEWRAHIPVAIKAINEGSMSEEDFIEEAKVMMK
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Template Sequence  YGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIK. . . . . . . EFIEEAKVMMN
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GGGB

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TT
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   392.......400.........410.........420.........430... ......440....
 
   321........330.........340.........350.........360.........370.........380
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Query Sequence  LSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLRERKGQLQKALLLSMCQDICEGMAY
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Template Sequence  LSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEY
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   452.......460.........470.........480.........490.........500.........510.
 
   381........390.........400.........410.........420.........430.........440
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Query Sequence  LERSCYIHRDLAARNCLVSSACVVKISDFGMARYVLDDEYISSSGAKFPVKWCPPEVFHF
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Template Sequence  LESKQFLHRDLAARNCLVNDQGVVKVSDFGFP. . . . . . . . . . . . . . . . . VRWSPPEVLMY
Template Known Secondary structure  TT


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SGGG
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   512.......520.........530.........540... ......550....
 
   441........450.........460.........470.........480.........490.........500
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Query Sequence  NKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISQGFRLYRPHLAPMTIYRVMY
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Template Sequence  SKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMY
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   572.......580.........590.........600.........610.........620.........630.
 
   501........510.........520.....
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Query Sequence  SCWHESPKGRPTFAELLQVLTEIAE
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Template Sequence  SCWHEKADERPTFKILLSNILDVMD
Template Known Secondary structure  TT
SSGGGS

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   632.......640.........650......
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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