Job Description P42682 Confidence 100.00% Date Tue Jul 30 13:16:14 BST 2013 Rank 58 Aligned Residues 259 % Identity 31% Template c3eygA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 1.90 Å

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		262	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.						.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.
Predicted Secondary structure																																.	.	.	.	.
Query SS confidence																																.	.	.	.	.
Query Sequence		E	K	W	E	I	D	P	S	E	L	A	F	V	K	E	I	G	S	G	Q	F	G	V	V	H	L	G	E	W	R	.	.	.	.	.	A	H	I	P	V	A	I	K	A	I	N	E	G	S	M	S	E	E	D	F	I	E	E	A	K
Query Conservation																																.	.	.	.	.
Alig confidence																																.	.	.	.	.												.	.	.
Template Conservation																																																.	.	.
Template Sequence		D	P	T	H	F	E	K	R	F	L	K	R	I	R	D	L	G	E	G	H	F	G	K	V	E	L	C	R	Y	D	P	E	G	D	N	T	G	E	Q	V	A	V	K	S	L	K	.	.	.	P	H	I	A	D	L	K	K	E	I	E
Template Known Secondary structure			T	T	S			G	G	G											S	S										T	T	S	S	S		S										.	.	.
Template Predicted Secondary structure																																																.	.	.
Template SS confidence
		866	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.				.	.	.	.	.	.	.	.	920	.	.
		317	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	M	M	K	L	S	H	S	R	L	V	Q	L	Y	G	V	C	I	Q	Q	K	P	L	Y	I	V	T	E	F	M	E	N	G	C	L	L	D	Y	L	R	E	R	K	G	Q	L	Q	K	A	L	L	L	S	M	C	Q	D	I	C	E
Query Conservation
Alig confidence																	.
Template Conservation																	.
Template Sequence		I	L	R	N	L	Y	H	E	N	I	V	K	Y	K	G	.	I	C	T	E	N	G	I	K	L	I	M	E	F	L	P	S	G	S	L	K	E	Y	L	P	K	N	K	N	K	I	N	L	K	Q	Q	L	K	Y	A	V	Q	I	C	K
Template Known Secondary structure					T				T	T	B						.															T	T		B					T	G	G	G	T	T	T
Template Predicted Secondary structure																	.
Template SS confidence
		928	.	930	.	.	.	.	.	.	.	.	.	940	.	.		.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.
		377	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	M	A	Y	L	E	R	S	C	Y	I	H	R	D	L	A	A	R	N	C	L	V	S	S	A	C	V	V	K	I	S	D	F	G	M	A	R	Y	V	L	D	D	E	Y	I	S	S	S	G	A	K	F	P	V	K	W	C	P	P	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	M	D	Y	L	G	S	R	Q	Y	V	H	R	D	L	A	A	R	N	V	L	V	E	S	E	H	Q	V	K	I	G	D	F	G	L	T	K	A	I	E	T	D	K	E	T	V	K	D	D	R	D	S	P	V	F	W	Y	A	P	E
Template Known Secondary structure									T	T				S			S	G	G	G						T	T								T	T						T	T					S			T	T			G	G	G
Template Predicted Secondary structure
Template SS confidence
		990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.
		437	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.																.	.	470	.	.	.	.	.	.	.	.	.	480	.
Predicted Secondary structure																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		V	F	H	F	N	K	Y	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	V	F	T	E	G	K	M	P	F	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	N	K	S	N	L	Q	V	V	E	A	I	S	Q
Query Conservation																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																											.						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																											.
Template Sequence		C	L	M	Q	S	K	F	Y	I	A	S	D	V	W	S	F	G	V	T	L	H	E	L	L	T	.	Y	C	D	S	D	S	S	P	M	A	L	F	L	K	M	I	G	P	T	H	G	Q	M	T	V	T	R	L	V	N	T	L	K	E
Template Known Secondary structure																										T	.	T	T		G	G	G												S			G	G	G											T
Template Predicted Secondary structure																											.
Template SS confidence
		1052	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.		.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110
		482	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	F	R	L	Y	R	P	H	L	A	P	M	T	I	Y	R	V	M	Y	S	C	W	H	E	S	P	K	G	R	P	T	F	A	E	L	L	Q	V	L	T	E	I	A	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		G	K	R	L	P	C	P	P	N	C	P	D	E	V	Y	Q	L	M	R	K	C	W	E	F	Q	P	S	N	R	T	S	F	Q	N	L	I	E	G	F	E	A	L	L	K
Template Known Secondary structure		T							T	T												T			S	S	G	G	G	S												T	T
Template Predicted Secondary structure
Template SS confidence
		1111	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D