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Job DescriptionP42682
Confidence100.00%DateTue Jul 30 13:16:14 BST 2013
Rank184Aligned Residues258
% Identity36%Templatec2yhvA_
PDB info PDB header:transferaseChain: A: PDB Molecule:alk tyrosine kinase receptor; PDBTitle: structure of l1196m mutant anaplastic lymphoma kinase
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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   262.......270.........280.........290.........300.. .......310.........
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Query Sequence  EKWEIDPSELAFVKEIGSGQFGVVHLGEWRAHIPVAIKAIN. . EGSMSEEDFIEEAKVMM
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Template Sequence  DLKEVPRKNITL. . . IRGLAFGEVYEGQV. . PLQVAVKTLPEVCSEQDELDFLMEALIIS
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   1107..1110........ .1120.........1130.. .......1140.........1150.........1160.
 
   320.........330.........340.........350....... ..360.........370...
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Query Sequence  KLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLRE. . . . . . RKGQLQKALLLSMCQD
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Template Sequence  KFNHQNIVRCIGVSLQSLPRFILMELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARD
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   1173......1180.........1190.........1200.........1210.........1220.........1230..
 
   374.....380.........390.........400.........410.........420.........430...
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Query Sequence  ICEGMAYLERSCYIHRDLAARNCLVSSACVVKISDFGMARYVLDDEYISSSGAKFPVKWC
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Template Sequence  IACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFG. . MARDIYRGGCAMLPVKWM
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   1233......1240.........1250.........1260.........1270.. .......1280.........1290
 
   434.....440.........450.........460.........470.........480.........490...
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Query Sequence  PPEVFHFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISQGFRLYRPHLAPM
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Template Sequence  PPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPG
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   1297..1300.........1310.........1320.........1330.........1340.........1350......
 
   494.....500.........510.........520......
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Query Sequence  TIYRVMYSCWHESPKGRPTFAELLQVLTEIAET
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Template Sequence  PVYRIMTQCWQHQPEDRPNFAIILERIEYCTQD
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   1357..1360.........1370.........1380.........
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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