Job Description P42682 Confidence 100.00% Date Tue Jul 30 13:16:14 BST 2013 Rank 6 Aligned Residues 421 % Identity 40% Template c2c0iA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 Resolution 2.30 Å Model Dimensions (Å) X:65.281 Y:69.185 Z:54.561

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		84	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.		.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.
Predicted Secondary structure																																											.
Query SS confidence																																											.
Query Sequence		R	I	Q	V	K	A	L	Y	D	F	L	P	R	E	P	G	N	L	A	L	K	R	A	E	E	Y	L	I	L	E	R	C	D	P	H	W	W	K	A	R	D	.	R	F	G	N	E	G	L	I	P	S	N	Y	V	T	E	N	R	L
Query Conservation																																											.
Alig confidence																																	.										.																		.
Template Conservation																																	.																												.
Template Sequence		R	I	I	V	V	A	L	Y	D	Y	E	A	I	H	H	E	D	L	S	F	Q	K	G	D	Q	M	V	V	L	E	E	.	S	G	E	W	W	K	A	R	S	L	A	T	R	K	E	G	Y	I	P	S	N	Y	V	A	R	V	D	.
Template Known Secondary structure								S	S		B				S	S	S	B			B		T	T									.		T	T							T	T	T								G	G	G				T	T	.
Template Predicted Secondary structure																																	.																												.
Template SS confidence
		59	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.		90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.
		143	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.		.	.	.	170	.	.	.	.	.	.	.	.	.	180		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200
Predicted Secondary structure																										.															.
Query SS confidence																										.															.
Query Sequence		A	N	L	E	I	Y	E	W	Y	H	K	N	I	T	R	N	Q	T	E	R	L	L	R	Q	.	E	A	K	E	G	A	F	I	V	R	D	S	R	H	.	L	G	S	Y	T	I	S	V	F	T	R	A	R	R	H	T	Q	S	S	I
Query Conservation																										.															.
Alig confidence		.																								.															.														.
Template Conservation		.																																																					.
Template Sequence		.	S	L	E	T	E	E	W	F	F	K	G	I	S	R	K	D	A	E	R	Q	L	L	A	P	G	N	M	L	G	S	F	M	I	R	D	S	E	T	T	K	G	S	Y	S	L	S	V	R	D	Y	D	P	.	R	Q	G	D	T	V
Template Known Secondary structure		.	S	G	G	G	S	T	T			T	T											T	S	T	T			T	T								S	S	S	T	T											T	.	T	T
Template Predicted Secondary structure		.																																																					.
Template SS confidence
			117	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.		.	170	.	.	.	.
		201	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260
Predicted Secondary structure
Query SS confidence
Query Sequence		K	H	Y	Q	I	K	K	N	D	S	G	Q	W	Y	I	T	E	R	H	L	F	P	S	V	P	E	L	I	Q	Y	H	Q	Y	N	A	A	G	L	I	S	R	L	R	Y	P	I	G	L	L	G	S	C	L	P	A	T	S	G	F	S
Query Conservation
Alig confidence																																																								.	.	.	.
Template Conservation																																																								.	.	.	.
Template Sequence		K	H	Y	K	I	R	T	L	D	N	G	G	F	Y	I	S	P	R	S	T	F	S	T	L	Q	E	L	V	D	H	Y	K	K	G	N	D	G	L	C	Q	K	L	S	V	P	C	M	S	S	K	P	Q	K	P	.	.	.	.	W	E
Template Known Secondary structure							B			S	T	T				S	S	T	T	S			S	S								T	T	S	S		S	S		S	S				S	B										.	.	.	.
Template Predicted Secondary structure																																																								.	.	.	.
Template SS confidence
		175	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.					.	230
		261	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	E	K	W	E	I	D	P	S	E	L	A	F	V	K	E	I	G	S	G	Q	F	G	V	V	H	L	G	E	W	R	A	H	I	P	V	A	I	K	A	I	N	E	G	S	M	S	E	E	D	F	I	E	E	A	K	V	M	M	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	D	A	W	E	I	P	R	E	S	L	K	L	E	K	K	L	G	A	G	Q	F	G	E	V	W	M	A	T	Y	N	K	H	T	K	V	A	V	K	T	M	K	P	G	S	M	S	V	E	A	F	L	A	E	A	N	V	M	K	T
Template Known Secondary structure		T	T		S	B			G	G	G											T	T									T	T	T												S	S														T
Template Predicted Secondary structure
Template SS confidence
		231	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290
		321	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																										.
Query SS confidence																																										.
Query Sequence		L	S	H	S	R	L	V	Q	L	Y	G	V	C	I	Q	Q	K	P	L	Y	I	V	T	E	F	M	E	N	G	C	L	L	D	Y	L	R	E	R	K	G	.	Q	L	Q	K	A	L	L	L	S	M	C	Q	D	I	C	E	G	M	A
Query Conservation																																										.
Alig confidence															.																											.
Template Conservation															.
Template Sequence		L	Q	H	D	K	L	V	K	L	H	A	V	V	.	T	K	E	P	I	Y	I	I	T	E	F	M	A	K	G	S	L	L	D	F	L	K	S	D	E	G	S	K	Q	P	L	P	K	L	I	D	F	S	A	Q	I	A	E	G	M	A
Template Known Secondary structure					T	T	B								.		S	S	S									T	T		B							S	T	T	G	G	G
Template Predicted Secondary structure															.
Template SS confidence
		291	.	.	.	.	.	.	.	.	300	.	.	.		.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.
		380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	L	E	R	S	C	Y	I	H	R	D	L	A	A	R	N	C	L	V	S	S	A	C	V	V	K	I	S	D	F	G	M	A	R	Y	V	L	D	D	E	Y	I	S	S	S	G	A	K	F	P	V	K	W	C	P	P	E	V	F	H
Query Conservation
Alig confidence																																				.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																				.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		F	I	E	Q	R	N	Y	I	H	R	D	L	R	A	A	N	I	L	V	S	A	S	L	V	C	K	I	A	D	F	G	L	A	R	.	.	.	.	.	.	.	.	.	.	.	.	.	V	I	P	I	K	W	T	A	P	E	A	I	N
Template Known Secondary structure						T	T				S			S	G	G	G					T	T								T	T	G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	T			G	G	G	S
Template Predicted Secondary structure																																				.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.														.	.	.	.	.	.	390	.	.	.	.	.	.
		440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	N	K	Y	S	S	K	S	D	V	W	S	F	G	V	L	M	W	E	V	F	T	E	G	K	M	P	F	E	N	K	S	N	L	Q	V	V	E	A	I	S	Q	G	F	R	L	Y	R	P	H	L	A	P	M	T	I	Y	R	V	M
Query Conservation
Alig confidence
Template Conservation
Template Sequence		F	G	S	F	T	I	K	S	D	V	W	S	F	G	I	L	L	M	E	I	V	T	Y	G	R	I	P	Y	P	G	M	S	N	P	E	V	I	R	A	L	E	R	G	Y	R	M	P	R	P	E	N	C	P	E	E	L	Y	N	I	M
Template Known Secondary structure																							T	T	T			S	S	T	T												T	T							T	T
Template Predicted Secondary structure
Template SS confidence
		410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.
		500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	S	C	W	H	E	S	P	K	G	R	P	T	F	A	E	L	L	Q	V	L	T	E	I	A	E	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	R	C	W	K	N	R	P	E	E	R	P	T	F	E	Y	I	Q	S	V	L	D	D	F	Y	T	A
Template Known Secondary structure					T		S	S	G	G	G	S												T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.